Results 121 to 130 of about 10,962,408 (345)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
WP 31 - How Many Hours Do You Usually Work: an analysis of the working hours questions in 26 large-scale surveys in 6 countries and the European Union [PDF]
This paper reviews how working hours are asked in 26 large-scale surveys in 6 countries plus the European Union. Four dimensions of working time were investigated, notably number of working hours, timing of work, predictability and control over hours ...
Dragstra, A.E., Kea Tijdens
core
Quarterly Journal of EconomicsThis paper uses labor force surveys from 160 countries to build a new microdatabase on hours worked covering 97% of the world population in cross section. We also construct time series spanning over 20 years in 86 countries.
A. Gethin, Emmanuel Saez
semanticscholar +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Frontiers in EndocrinologyBackgroundPrevious research has indicated that long working hours are connected to a variety of health conditions, including nonalcoholic fatty liver disease (NAFLD). However, this association which has been observed in more population is limited.
Ruli Wang +8 more
doaj +1 more source
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Chapter 3: Longer Working Hours - the Beginning of a new Trend? [PDF]
This chapter reviews working time developments in Western Europe. The main issue is whether recent agreements on longer working time (at unchanged pay) in Germany represent a reversal of the earlier trend towards shorter working time that could also ...
Hans-Werner Sinn +7 more
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Actual and preferred working hours [PDF]
, 2001 In this paper, we use data from the British Household Panel Survey to test the traditional labour supply model by investigating whether subjective data on desired labour supply provide information on future adjustment of actual hours worked.
Böheim, René, Taylor, Mark P.
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STRESSORS IN NURSING WITH DOUBLE OR MORE WORKING HOURS
Revista de Pesquisa Cuidado é Fundamental Online, 2013 Resumo Objetivo: investigar os principais agentes estressores nos trabalhadores de enfermagem com dupla ou mais jornada de trabalho; verificar os principais sinais e sintomas indicadores de estresse.
Marlinir Bezerra de Lima +4 more
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source