Results 131 to 140 of about 7,820,715 (391)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Scandinavian Journal of Work, Environment and Health, 2018 Objectives This systematic review and meta-analysis combined published study-level data and unpublished individual-participant data with the aim of quantifying the relation between long working hours and the onset of depressive symptoms.
M. Virtanen +37 more
semanticscholar +1 more source
Mismatches between actual and preferred work time: empirical evidence of hours constraints in 21 countries [PDF]
This paper analyzes the discrepancy between actual and desired working hours in a multinational setting. Using the latest data of the International Social Survey Program (ISSP) with a focus on work orientations hours constraints in 21 heterogeneous ...
Otterbach, Steffen
core
Actual and preferred working hours [PDF]
, 2001 In this paper, we use data from the British Household Panel Survey to test the traditional labour supply model by investigating whether subjective data on desired labour supply provide information on future adjustment of actual hours worked.
Böheim, René, Taylor, Mark P.
core
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
International Journal of Obesity, 2019 Objective To examine the relation between long working hours and change in body mass index (BMI). Methods We performed random effects meta-analyses using individual-participant data from 19 cohort studies from Europe, US and Australia ( n = 122,078 ...
M. Virtanen +30 more
semanticscholar +1 more source
WP 31 - How Many Hours Do You Usually Work: an analysis of the working hours questions in 26 large-scale surveys in 6 countries and the European Union [PDF]
This paper reviews how working hours are asked in 26 large-scale surveys in 6 countries plus the European Union. Four dimensions of working time were investigated, notably number of working hours, timing of work, predictability and control over hours ...
Dragstra, A.E., Kea Tijdens
core
Availability and accessibility to latrine and handwashing facilities during working hours among “boda-boda” drivers in Mwanza city [PDF]
, 2023 Namanya Basinda +9 more
openalex +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source