Results 141 to 150 of about 10,962,408 (345)
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Can Family-Support Policies Help Explain Differences in Working Hours Across Countries? [PDF]
It has been suggested in the literature that taxes and subsidies play an important role in explaining the differences in working hours across countries.
Urban Sila
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Hours of work and retirement behavior [PDF]
Using a novel dataset from the 2006 Portuguese Labor Force Survey this paper examines the impact of a voluntary reduction in hours of work, before retirement, on the moment of exit from the labor force.
C. Sofia Machado, Miguel Portela
core +2 more sources
Physical activity of graduated nurses in one-and multiple-shift work
Obzornik zdravstvene nege, 2016 Introduction: Physical activity enables nurses to better control their mental and physical strain at work, which is important for ensuring quality patient treatment.
Vanja Škrbina, Joca Zurc
doaj +1 more source
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
Effective working hours and wages: the case of downward adjustment via paid absenteeism [PDF]
, 2009 This paper compares contractual with effective working hours and wages, respectively. Effective working hours are defined as contractual working hours minus absent working hours.
Pfeifer, Christian
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International Review of Management and Marketing, 2019 Employee engagement is one of the concentrations of the human resources department. Many programs are run to increase employee engagement value from year to year.
Aris Setiyani +3 more
semanticscholar +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Work Hours Constraints: Impacts and Policy Implications [PDF]
If individuals reveal their preference as consumers, then they are taken seriously. What happens if individuals, as employees, reveal their preferences in working hours?
Constant, Amelie F., Otterbach, Steffen
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Female professionals’ working hours [PDF]
, 2005 The aim of this paper is to examine female professionals’ working hours, particularly the tendency to work reduced hours. Earlier research indicates a considerable variation in female professionals’ working hours (Hoel 1995, Ellingsæther 1995, Burchell ...
Abrahamsen, Bente
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