Results 61 to 70 of about 1,396,249 (309)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Determining the Layout Parameters of the Gas Drainage Roadway: A Study for Sima Coalmine China

open access: yesAdvances in Civil Engineering, 2021
To determine the layout parameters of the gas drainage roadway (GDR) serving for the working face, an analytical calculation method of fracture zone and the modelling experiment were adopted, and the overburden fissure induced by mining and the height of
Zhiliu Wang   +5 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

ESTIMATION OF DUST DISPERSE COMPOSITION OF FERROUS CASTING SECTION

open access: yesВестник Донского государственного технического университета, 2018
Theoretical and experimental data on chemical, disperse composition of foundry dust are analyzed. Parameters of true density of dust coming out of sandblast machines and the section of castings shakeout from moulds of PLC “Rostvertol” have been ...
I.A. IVANOVA, V.Y. MANOKHIN
doaj  

Observation of “Three Zones” of Spontaneous Combustion in Goaf Under the Influence of Gas Drainage in Outburst Coal Seam

open access: yesMeikuang Anquan, 2020
In view of the working face of coal and gas outburst, adopting the measures of gas drainage and outburst elimination will increase the air leakage in the goaf, and then change the flow field in the goaf, resulting in too long oxidation zone in the goaf,
LI Xin, LIU Dongming, TANG Hui, WANG Bo
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

PERFORMANCE EVALUATION OF MULTIPURPOSE ELECTRIC COLLECTORS AS PROTECTION FRAMES OF AIR OF A WORKING ZONE AT DRAWING OF ELECTRODEPOSITS

open access: yesВестник Донского государственного технического университета, 2018
Research results of the efficiency of multipurpose superterranean electrocatchers of harmful galvanic sprays with various geometry of electrodes and electric fields are presented.
Vladimir L. GAPONOV, Vladimir I. GARSHIN
doaj  

Thermal exchange effects on steel thixoforming processes [PDF]

open access: yes, 2010
Steel thixoforging is an innovative semi-solid forming process. It allows the manufacturing of complex parts and minimises the forming load. This work aims to identify and characterise the main feature zones of a thixoforging part.
BECKER, Eric   +2 more
core   +6 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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