Trends in tuberculosis incidence and their determinants in 134 countries
Bulletin of the World Health Organization, 2009 OBJECTIVE: To determine whether differences in national trends in tuberculosis incidence are attributable to the variable success of control programmes or to biological, social and economic factors.
C Dye +4 more
doaj
Global progress on the elimination of viral hepatitis as a major public health threat: an analysis of WHO Member State responses 2017 [PDF]
, 2019 Blach +22 more
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Ambient air pollution: a global assessment of exposure and burden of disease
Clean Air Journal, 2016 World Health Organization
doaj +1 more source
Global Health ActionThis paper presents the structured process developed by the World Health Organization (WHO) to systematically scale up actions in environment, climate change, and health at the country level.
Jennyfer Wolf +10 more
doaj +1 more source
Fall prevention for people with learning disabilities: key points and recommendations for practitioners and researchers [PDF]
, 2018 National Institute for Health Care and Excellence (NICE) +2 more
core +2 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Development assistance for health: should policy-makers worry about its macroeconomic impact?
Bulletin of the World Health OrganizationMany low-income countries need to substantially increase expenditure to meet universal coverage goals for essential health services but, because they have very low-incomes, most will be unable to raise adequate funds exclusively from domestic sources in ...
Eleonora Cavagnero +3 more
doaj +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source