Results 151 to 160 of about 22,062 (274)

Engineered Optogenetic Circuits In Yeast with Self‐Sustained Outputs

Advanced Science, EarlyView.
Optogenetic quorum‐sensing (OptoQS) circuit enables Saccharomyces cerevisiae to record transient light stimulus with self‐sustained outputs. Panel a indicates the design of the OptoQS circuit based on G‐protein coupled receptor (GPCR) signaling cascade. Panel b indicates the mode of action of surrogate messenger‐mediated signal transmission at the cell
Cong Fan, Haofeng Chen, Yan Wang, Junyi Wang, Yueyang Chen, Yang Zhang, Jinting Guan, Jifeng Yuan   +7 more
wiley   +1 more source

Application of Cancer Screening Guidelines in Resource Limited Settings. [PDF]

Cancer Control
Varghese C, Nongkynrih B, Lohiya A, Prasad A, Barango P.   +4 more
europepmc   +1 more source

KRT14 Drives Basal Muscle‐Invasive Bladder Cancer Progression and Lung Metastasis by Directly Binding to and Stabilizing IGF2BP1

Advanced Science, EarlyView.
We identified a Krt14+ Igf2bp1+ bladder cancer population linked to EMT. Mechanistically, KRT14 stabilizes and transports IGF2BP1 to invasive protrusions, initiating a positive feedback loop that drives metastasis and poor outcomes. ABSTRACT Basal‐type muscle‐invasive bladder cancer (BMIBC) is characterized by aggressive metastasis and poor prognosis ...
Shirui Huang, Zhihan Zhou, Qipeng Xie, Zheng Wang, Lijiong He, Yutong Liu, Lijuan Huang, Liuxian Ye, Limeng Hu, Baokun Li, Yang Wang, Xiaohui Hua, Xuelei Liu, Yunping Zhao, Jingxia Li, Jinfei Chen, Guiying Wang, Xian Shen, Wei Chen, Chuanshu Huang   +19 more
wiley   +1 more source

Intramolecular Interactions between Folded and Disordered Regions Shape Ubiquilin Structure and Function

Advanced Science, EarlyView.
Ubiquilin (UBQLN), like many other human proteins, contains both well‐folded and disordered regions. Here, we show that intramolecular interactions between disordered regions and folded domains modulate between open and closed topologies of UBQLN proteins, altering their structure and function.
Jessica K. Niblo, Nirbhik Acharya, Maxwell B. Watkins, Carlos A. Castañeda, Shahar Sukenik   +4 more
wiley   +1 more source

Artificial intelligence computed tomography models for the discrimination of Wilms versus non-Wilms tumors: systematic review and meta-analysis. [PDF]

J Bras Nefrol
Ardicli B.
europepmc   +2 more sources

Evaluating the Therapeutic Potential of MRT68921 and Afatinib in Three-Dimensional Models of Epithelial Ovarian Cancer. [PDF]

Cancers (Basel)
Johnston TPA, Webb JD, Borrelli MJ, Tomas EJ, Pucchio ÁC, Valdés YR, Shepherd TG.   +6 more
europepmc   +1 more source

Encounter of Faith and the World. Contribution of Romano Guardini to the Principle of Correlation

, 2005
Polazeći od razmatranja načela korelacije, po kojem se u teologiji nastoji ostvariti plodan suodnos objave i ljudskog života, vjere i ljudskog iskustva, autor definira svoj zadatak kao istraživanje pitanja, da li se u teologiji Romana Guardinija (1885 ...
Zalar, Đuro, Đuro Zalar
core  

A Wireless 3D Magneto‐Mechanical Stimulation Platform Drives In Situ Chondrogenic Commitment of Endogenous MSCs

Advanced Science, EarlyView.
An intracellular magneto‐mechanical platform utilizing MSC‐targeted nanomotors is developed. After intra‐articular delivery, these nanomotors target endogenous BMSCs and are actuated within lysosomes to execute trans‐planar rotational‐bouncing motions under a rotating‐fluctuating 3D magnetic field, generating amplified mechanical stimulation.
Zhenguang Li, Li Peng, Laiya Lu, Yingying Wang, Xiaolei Chen, Feng Yin, Cuijun Deng, Yu Cheng   +7 more
wiley   +1 more source

The risks and bottlenecks to automation in employment in Argentina. New impacts on the occupational structure in selected economic sectors. [PDF]

Front Sociol
Chávez Molina E, Rodríguez de la Fuente J.   +1 more
europepmc   +1 more source

CONSTITUTIONAL MEANING OF THE DECISIONS OF TERRITORIAL ANTIFASCIST COUNCIL OF NATIONAL LIBERATION OF CROATIA FOR THE DEVELOPMENT OF CROATIAN NATIONAL SOVEREIGNTY IN THE WORLD WAR TWO

, 1995
Autor u šest poglavlja analizira odluke ZAVNOH-a koje su imale državnopravno značenje za izgradnju državnosti Hrvatske u drugom svjetskom ratu. Autor posebno analizira sadržaj odluka prvog, drugog i trećeg zasjedanja ZAVNOH-a, stvaranje Suda ZAVNOH-a i ...
Sirotković, Hodimir, Hodimir Sirotković   +1 more
core