Results 91 to 100 of about 1,032,718 (308)
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
An Efficient Hidden Markov Model for Offline Handwritten Numeral Recognition [PDF]
Traditionally, the performance of ocr algorithms and systems is based on the recognition of isolated characters. When a system classifies an individual character, its output is typically a character label or a reject marker that corresponds to an ...
Hemanth, S., Saritha, B. S.
core
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
Women’s Roles in Negotiating Diasporic Identity in Jhumpa Lahiri’s Unnaccustomed Earth and Only Goodness [PDF]
Today diaspora becomes highligthed issue when people become parts of global world. The term of diapora cannot be separated from old world/new world, past/present, or rooted/uprooted.
Wulandari, Retno
core
Arithmetic Spacetime Geometry from String Theory
An arithmetic framework to string compactification is described. The approach is exemplified by formulating a strategy that allows to construct geometric compactifications from exactly solvable theories at $c=3$.
Conway J. H. +14 more
core +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Hematopoietic (stem) cells—The elixir of life?
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
«Speak no more of her»: Silencing the Feminine Voice in Shakespeare’s «Julius Caesar»
Although the female characters in Julius Caesar are given little stage time and are ill-treated by their husbands, this article shows that it is not a misogynous play, but a play which effectively depicts a misogynous world. On the one hand, it validates
Natalie Roulon
doaj +1 more source

