Results 81 to 90 of about 84,971,721 (293)

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

Comparing university rankings

, 2010
Recently there is increasing interest in university rankings. Annual rankings of world universities are published by QS for the Times Higher Education Supplement, the Shanghai Jiao Tong University, the Higher Education and Accreditation Council of Taiwan
Levene, Mark, Aguillo, I.F., Ortega, J.L., Bar-Ilan, J., Luisa Vásquez, Carmen, Mark Levene, José Ortega, Torres-Samuel , Maritza, Luna cardozo, Marisabel, Judit Bar-Ilan, Bucci, Nunziatina, Isidro Aguillo, amelec, viloria, Cabrera, Danelys, José Luis Ortega, Isidro F. Aguillo   +15 more
core   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Which journal rankings best explain academic salaries? Evidence from the University of California [PDF]

, 2012
The ranking of an academic journal is important to authors, universities, journal publishers and research funders. Rankings are gaining prominence as countries adopt regular research assessment exercises that especially reward publication in high impact ...
Tressler, John, Gibson, John, Anderson, David L.   +2 more
core   +1 more source

The Method of League Analysis and Its Application in Comparing Global University Rankings and Russia’s University Performance Monitoring

Вопросы образования, 2019
A new technique called Method of Analysis of Leagues (MethALeague) is proposed for comparing performance of higher education institutions measured by different assessment methods.
Vladimir Navodnov, Galina Motova, Olga Ryzhakova   +2 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

The mismeasure of higher education? The corrosive effect of university rankings

Ethics in Science and Environmental Politics, 2013
This paper examines the limitations and biases of world university rankings and asks what drivers explain their ongoing proliferation and popularity. It is argued that rankings are having a corrosive effect on higher education systems, institutions and ...
D Robinson
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Identification оf World Class Universities

Мир новой экономики, 2018
The article discusses the concept of world-class universities and the author’s understanding of the term, allowing not only to identify these objects but also to quantify their international potential.
E. V. Balatsky, N. A. Ekimova
doaj