Results 1 to 10 of about 334,251 (216)

Systematic analysis of lysine crotonylation in human macrophages responding to MRSA infection

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most commonly encountered bacteria found in healthcare clinics and has been ranked a priority 2 pathogen.
Hao Zhang   +12 more
doaj   +1 more source

The Host CYP1A1-Microbiota Metabolic Axis Promotes Gut Barrier Disruption in Methicillin-Resistant Staphylococcus aureus-Induced Abdominal Sepsis

open access: yesFrontiers in Microbiology, 2022
BackgroundHost-microbiota crosstalk has been implicated in multiple host metabolic pathway axes that regulate intestinal barrier function. Although constitutive cytochrome P4501A1 (CYP1A1) expression perturbs the microbiome-derived autoregulatory loop ...
Xiaoyuan Ma   +13 more
doaj   +1 more source

Natural killer cells in sepsis: Friends or foes?

open access: yesFrontiers in Immunology, 2023
Sepsis is one of the major causes of death in the hospital worldwide. The pathology of sepsis is tightly associated with dysregulation of innate immune responses.
Fangjie Wang   +4 more
doaj   +1 more source

Correction to: Cytochrome P450 1A1 enhances inflammatory responses and impedes phagocytosis of bacteria in macrophages during sepsis

open access: yesCell Communication and Signaling, 2020
An amendment to this paper has been published and can be accessed via the original article.
Li-Xing Tian   +11 more
doaj   +1 more source

Cytochrome P450 1A1 enhances inflammatory responses and impedes phagocytosis of bacteria in macrophages during sepsis

open access: yesCell Communication and Signaling, 2020
The hydroxylase cytochrome P450 1A1 (CYP1A1) is regulated by the inflammation-limiting aryl hydrocarbon receptor (AhR), but CYP1A1 immune functions remain unclear.
Li-Xing Tian   +11 more
doaj   +1 more source

A multiomics approach to identify host-microbe alterations associated with infection severity in diabetic foot infections: a pilot study

open access: yesnpj Biofilms and Microbiomes, 2021
Diabetic foot infections (DFIs) are a major cause of hospitalization and can lead to lower extremity amputation. In this pilot study, we used a multiomics approach to explore the host–microbe complex within DFIs.
Michael Radzieta   +9 more
doaj   +1 more source

Inhibitory effect and underlying mechanism of hepatocytes on bacterial proliferation

open access: yes陆军军医大学学报, 2023
Objective To explore the role and mechanism of hepatocytes in inhibiting bacterial proliferation by phagocytizing bacteria directly and mediating the expression of antibacterial proteins indirectly.
MA Wei   +4 more
doaj   +1 more source

LPS inhibits arginase-1 expression in macrophages by up-regulating activity of cytochrome P450 1A1 epoxidase

open access: yes陆军军医大学学报, 2023
Objective To explore the regulative effect and mechanism of cytochrome P450 1A1 (CYP1A1) on regulating lipopolysaccharide (LPS)-induced arginase-1 (Arg-1) expression in macrophages. Methods After mouse macrophage-like cell line RAW264.7 (RAW) was treated
TIAN Lixing   +3 more
doaj   +1 more source

Knockout of cytochrome P450 1A1 enhances lipopolysaccharide‐induced acute lung injury in mice by targeting NF‐κB activation

open access: yesFEBS Open Bio, 2020
Acute lung injury (ALI) is accompanied by overactivation of multiple pro‐inflammatory factors. Cytochrome P450 1A1 (CYP1A1) has been shown to aggravate lung injury in response to hyperoxia. However, the relationship between CYP1A1 and lipopolysaccharide (
Li‐xing Tian   +8 more
doaj   +1 more source

Home - About - Disclaimer - Privacy