Results 61 to 70 of about 4,201,473 (405)

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Vacuum-assisted closure (VAC®) systems and microbiological isolation of infected wounds

World Journal of Emergency Surgery, 2018
Background Negative pressure wound therapy is now largely used to treat infected wounds. The prevention and reduction of healthcare-associated infections is a high priority for any Department of Health and great efforts are spent to improve infection ...
Valerio Cozza, Gilda Pepe, Marco Cintoni, Flavio De Maio, Giuseppe Tropeano, Sabina Magalini, Gabriele Sganga, Giovanni Delogu, Daniele Gui   +8 more
doaj   +1 more source

Meta-analysis and systematic review of skin graft donor-site dressings with future guidelines. [PDF]

, 2018
Background: Many types of split-thickness skin graft (STSG) donor-site dressings are available with little consensus from the literature on the optimal dressing type. The purpose of this systematic review was to analyze the most recent outcomes regarding
Alwaal, Assadian, Baser, Begg, Blount, Brown, Brölmann, Cheesborough, Chung, Cigna, Demirtas, Dickersin, Druery, Fearmonti, Feldman, Fernandes de Carvalho, Ferreira, Ghieh, Goertz, Haith, Hasatsri, Hassanpour, Healy, Iwuagwu, Jadad, Junker, Kaiser, Konieczynska, Konieczynska, Konieczynska, Lairet, Liu, Lohsiriwat, Massand, McCartan, Metelmann, Moher, Muangman, Petruzzelli, Polfer, Potocká, Quinn, Rakel, Ratner, Salehi, Selig, Serino, Singh, Siritientong, Soltan Dallal, Tan, Tanaka, Vaghardoost, Vejdan, Villa-Camacho, Voineskos, Wiechula, Wisely, Zidan   +58 more
core   +1 more source

Novel and unscrutinized immune entities of the zebrafish gut

FEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil, Marine Mantel, Julia Soh, Serge Mostowy, Sylvia Brugman, Gilles Claude Vanwalleghem   +5 more
wiley   +1 more source

Trichophyton as a Rare Cause of Postoperative Wound Infection Resistant to Standard Empiric Antimicrobial Therapy

Case Reports in Pediatrics, 2018
Fungal infections are rare causes of acute surgical wound infections, but Candida is not an infrequent etiology in chronic wound infections. Trichophyton species is a common cause of tinea capitis but has not been reported as a cause of neurosurgical ...
Sheema Gaffar, John K. Birknes, Kenji M. Cunnion   +2 more
doaj   +1 more source

A Pilot Study for Enhancing Postpartum Discharge Instructions for Incision Care: Assessment of Comprehension [PDF]

, 2017
Literacy and Health Care • 14.5% of United States is illiterate 1 • Reading level of most medical forms is 10th grade 2 Improving Outcomes with a Visual Aid • Cesarean Surgical Site Infection (SSI) rate is 5% 3 • A patient with a SSI can be 2 times as
Baxter, MD, MSCP, Jason K., Cohen, BS, Sarah, Lawrence, BS, Rebecca, McCurdy, MD, Rebekah Jo   +3 more
core   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

An observational prospective study of topical acidified nitrite for killing methicillin-resistant Staphylococcus aureus (MRSA) in contaminated wounds [PDF]

, 2011
Background Endogenous nitric oxide (NO) kills bacteria and other organisms as part of the innate immune response. When nitrite is exposed to low pH, NO is generated and has been used as an NO delivery system to treat skin infections.
A Ghaffari, A Ghaffari, AD Ormerod, AD Ormerod, Amjad AJ Shah, Anthony D Ormerod, AP Johnson, C Miller, C Wendt, Carlo Leifert, CJ Yates, DJ Anderson, DL Monnet, F Jowkar, Gail P Ferguson, GW Dufresne, Hong Li, IM Gould, J Wilson, LR Martinez, M Barber, Nigel B Benjamin, R Goldman, R Phillips, R Phillips, R Weller, R Weller, R Weller, RS Dykhuizen, RS Dykhuizen, S Homer-Vanniasinkam   +30 more
core   +4 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source