Results 81 to 90 of about 251,564 (406)

Acute Acalculous Cholecystitis in Severe Trauma Patients: A Single Center Experience [PDF]

Journal of Acute Care Surgery, 2015
Purpose: Early diagnosis and prompt treatment of acute acalculous cholecystitis is important, because it is associated with high mortality. In major trauma patients, besides the direct damage the trauma itself causes, many complications can occur due to ...
Jong Beom Kim, Yun Su Mun, Oh Sang Kwon, Min Koo Lee, Joo Seung Park, Je Ho Jang   +5 more
doaj   +1 more source

Societal consequences of falls in the older population: Injuries, healthcare costs, and long-term reduced quality of life [PDF]

, 2011
BACKGROUND:: Fall incidents are a major cause of morbidity and mortality in older adults. The aim of this cohort study was to determine the incidence, costs, and quality of life for fall-related injuries in the older Dutch population presenting at the ...
Dolan, Gillespie, Greenspan, Hartholt, Hernandez, Kannus, Lyons, Lyons, Meerding, Mulder, O'Neill, Oostenbrink, Polinder, Sanders, Scheffer, Scuffham, Stalenhoef, Stel, Tan, Tidermark, van Staa, Watson   +21 more
core   +2 more sources

Endoglin mediates the tumor‐ and metastasis‐promoting traits of stromal myofibroblasts in human breast carcinomas

Molecular Oncology, EarlyView.
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo, Yoshihiro Mezawa, Zixu Wang, Ahmet Acar, Yasuhiko Ito, Atsushi Takano, Yohei Miyagi, Tomoyuki Yokose, Toshinari Yamashita, Yataro Daigo, Takuya Shirakihara, Akira Orimo   +11 more
wiley   +1 more source

A Case Report of Treatment of a Wound with Extensive Skin Necrosis Using Modern Dressing in a One-Month-Old Infant

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2019
Background and Objectives: A wound is an injury or rupture on the surface of skin, which is caused physically, chemically, mechanically, or by heat.   Case Report: The patient was a one-month-old infant who admitted to the hospital with seizure.
Robabeh Ahmadli, Narges Farshadpour, Zahra Kaffash   +2 more
doaj  

Chest wall reconstruction following a speedboat propeller injury [PDF]

, 2014
Propeller blade injuries to the chest are uncommon but can result in devastating injuries. We describe a case of a 44 year-old male scuba diver who was dragged by sea currents into the propeller of a speedboat. He suffered extensive chest wall trauma but
Casha, Aaron, Manche, Alexander, Sladden, David   +2 more
core  

Outcomes in patients with gunshot wounds to the brain. [PDF]

, 2019
Introduction:Gunshot wounds to the brain (GSWB) confer high lethality and uncertain recovery. It is unclear which patients benefit from aggressive resuscitation, and furthermore whether patients with GSWB undergoing cardiopulmonary resuscitation (CPR ...
Babcock, Jessica M, Berne, John, Bosarge, Patrick, Bruns, Brandon, Cabral, Donna, Chang, Grace, Chestovich, Paul J, Chow, Kevin L, Claridge, Jeffrey, Corsa, Joshua G, Costantini, Todd W, Cragun, Benjamin, Curry, Terry, Fraifogl, Joanne, Goldenberg-Sandau, Anna, Grigorian, Areg, Guidry, Chrissy, Gulmatico, Jhoanna, Gurney, Onaona, Hamrick, Amy V, Hu, Parker, Kaafarani, Haytham, Kincaid, Michelle Y, Kongwibulwut, Manasnun, Kutcher, Matthew E, Ladhani, Husayn A, Lee, Jane K, Logan, Melissa S, Lottenberg, Lawrence, Lunardi, Nicole, Massetti, Jennifer, McNickle, Allison G, Mederos, Dalier R, Mount, Michael, Nahmias, Jeffry, Noorbaksh, Matthew, Olson, Erik J, Parks, Jonathan J, Pascual, Jose L, Philp, Frances H, Pigneri, Danielle A, Quispe, Juan Carlos, Rattan, Rishi, Robinson, Bryce, Robinson, Leigh Anna, Sakran, Joseph Victor, San Roman, Janika, Schreiber, Craig, Smith, Alison A, Solomon, Rachele, Spalding, Chance, Turco, Lauren M, Uhlich, Rindi, Usmani, Farooq, Weinberger, Jason, Winfield, Robert D   +55 more
core   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

WSES classification and guidelines for liver trauma [PDF]

, 2016
The severity of liver injuries has been universally classified according to the American Association for the Surgery of Trauma (AAST) grading scale. In determining the optimal treatment strategy, however, the haemodynamic status and associated injuries ...
Abu-Zidan, Fikri M., Ansaloni, Luca, Biffl, Walter, Catena, Fausto, Ceresoli, Marco, Coccolini, Federico, Coimbra, Raul, Fraga, Gustavo, Ivatury, Rao, Kluger, Yoram, Montori, Giulia, Moore, Ernest E., Moore, Frederick A., Naidoo, Noel, Peitzman, Andrew, Rizoli, Sandro, Sartelli, Massimo, Weber, Dieter, Zanini, Nicola   +18 more
core   +2 more sources

Short peptide perturbs spermatogenesis via immune microenvironment dysregulation and mitochondrial imbalance

FEBS Open Bio, EarlyView.
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley   +1 more source

Heart Injury with Projectile Lodged Inside the Heart

Brazilian Journal of Cardiovascular Surgery
Penetrating heart injuries present high mortality rates. Increasing rates of urban violence have contributed to a significant rise in the number of heart injuries by firearm projectiles. Such injuries are associated with the highest mortality rates among
Marco Antônio Volpe, Jorge Edwin Morocho Paredes, Luciana Costacurta Redigolo, Isaac Samuel Moscoso Sanchez, Fernando Lanichek, Luiza Zita D'Albuquerque Silveira   +5 more
doaj   +1 more source