Abnormal Blink Reflex and Intermuscular Coherence in Writer's Cramp [PDF]
Frontiers in Neurology, 2018 Background: Writer's cramp (WC) is a task-specific focal hand dystonia presenting with pain, stiffness and/or tremor while writing. We explored the involvement of cortical and brainstem circuits by measuring intermuscular coherence (IMC) and pre-pulse ...
Supriyo Choudhury +9 more
doaj +4 more sources
Functional Neural Networks in Writer's Cramp as Determined by Graph-Theoretical Analysis [PDF]
Frontiers in Neurology, 2021 Dystonia, a debilitating neurological movement disorder, is characterized by involuntary muscle contractions and develops from a complex pathophysiology.
Jana Schill +9 more
doaj +2 more sources
Botulinum Toxin Therapy in Writer’s Cramp and Musician’s Dystonia [PDF]
Toxins, 2021 Task-specific focal dystonia is characterized by muscle contraction(s) during a specific task, resulting in abnormal postures or movements. Specifically, writer’s cramp involves the upper extremity during the act of writing.
Elina Zakin, David M. Simpson
doaj +2 more sources
Specific components of manual dexterity are affected in patients with writer’s cramp: an observational comparative study and preliminary rehabilitation report [PDF]
Journal of Rehabilitation MedicineObjective: To compare manual dexterity in patients with writer’s cramp and healthy controls to determine which components of dexterity are impaired in writer’s cramp. In addition, to assess the effects of rehabilitation.
Jean-Pierre Bleton +8 more
doaj +2 more sources
Abnormal effective connectivity in the sensory network in writer’s cramp [PDF]
NeuroImage: Clinical, 2021 Background: Writer’s cramp (WC), a task specific form of dystonia, is considered to be a motor network disorder, but abnormal sensory tactile processing has also been acknowledged. The sensory spatial discrimination threshold (SDT) can be determined with
Inken Tödt +8 more
doaj +2 more sources
Stereotactic Lesioning of the Thalamic Vo Nucleus for the Treatment of Writer's Cramp (Focal Hand Dystonia) [PDF]
Frontiers in Neurology, 2018 Writer's cramp (focal hand dystonia) is a sporadic focal dystonia that affects a specific part of the upper limb causing excessive co-contraction of antagonistic muscles.
Takeshi Shimizu +8 more
doaj +2 more sources
Splice-variant specific effects of a CACNA1H mutation associated with writer’s cramp [PDF]
Molecular Brain, 2021 The CACNA1H gene encodes the α1 subunit of the low voltage-activated Cav3.2 T-type calcium channel, an important regulator of neuronal excitability. Alternative mRNA splicing can generate multiple channel variants with distinct biophysical properties and
Ivana A. Souza +2 more
doaj +2 more sources
Transcranial Direct Current Stimulation Combined with Action Observation and Electromyographic Biofeedback Training in a Patient with Writer’s Cramp [PDF]
Journal of Movement Disorders, 2018 We present a 47-year-old right-handed woman with a 15-year history of writer’s cramp who was provided with six sessions of cathodal transcranial direct current stimulation (tDCS) combined with observation of writing actions performed by a healthy subject
Yohei Okada +7 more
doaj +2 more sources
Motor network reorganization associated with rTMS-induced writing improvement in writer's cramp dystonia [PDF]
Brain StimulationBackground: Writer's cramp (WC) dystonia is an involuntary movement disorder with distributed abnormalities in the brain's motor network. Prior studies established the potential for repetitive transcranial magnetic stimulation (rTMS) to either premotor ...
Noreen Bukhari-Parlakturk +22 more
doaj +2 more sources
Rare functional missense variants in CACNA1H: What can we learn from Writer’s cramp? [PDF]
Molecular Brain, 2021 Writer’s cramp (WC) is a task-specific focal dystonia that occurs selectively in the hand and arm during writing. Previous studies have shown a role for genetics in the pathology of task-specific focal dystonia.
Miaozhen Huang +12 more
doaj +2 more sources