Botulinum Toxin Therapy in Writer’s Cramp and Musician’s Dystonia [PDF]
Toxins, 2021 Task-specific focal dystonia is characterized by muscle contraction(s) during a specific task, resulting in abnormal postures or movements. Specifically, writer’s cramp involves the upper extremity during the act of writing.
Elina Zakin, David M. Simpson
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Abnormal effective connectivity in the sensory network in writer’s cramp [PDF]
NeuroImage: Clinical, 2021 Background: Writer’s cramp (WC), a task specific form of dystonia, is considered to be a motor network disorder, but abnormal sensory tactile processing has also been acknowledged. The sensory spatial discrimination threshold (SDT) can be determined with
Inken Tödt +8 more
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Specific components of manual dexterity are affected in patients with writer’s cramp: an observational comparative study and preliminary rehabilitation report [PDF]
Journal of Rehabilitation MedicineObjective: To compare manual dexterity in patients with writer’s cramp and healthy controls to determine which components of dexterity are impaired in writer’s cramp. In addition, to assess the effects of rehabilitation.
Jean-Pierre Bleton +8 more
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Splice-variant specific effects of a CACNA1H mutation associated with writer’s cramp [PDF]
Molecular Brain, 2021 The CACNA1H gene encodes the α1 subunit of the low voltage-activated Cav3.2 T-type calcium channel, an important regulator of neuronal excitability. Alternative mRNA splicing can generate multiple channel variants with distinct biophysical properties and
Ivana A. Souza +2 more
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Transcranial Direct Current Stimulation Combined with Action Observation and Electromyographic Biofeedback Training in a Patient with Writer’s Cramp [PDF]
Journal of Movement Disorders, 2018 We present a 47-year-old right-handed woman with a 15-year history of writer’s cramp who was provided with six sessions of cathodal transcranial direct current stimulation (tDCS) combined with observation of writing actions performed by a healthy subject
Yohei Okada +7 more
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Writing orthotic device for the management of writer's cramp [PDF]
Frontiers in Neurology, 2013 Background: Oral therapies and chemodenervation procedures are often unrewarding in the treatment of focal, task-specific hand disorders such as writer's cramp or primary writing tremor.
Narayanasarma V. Singam +2 more
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Predicting Improvement in Writer's Cramp Symptoms following Botulinum Neurotoxin Injection Therapy [PDF]
Tremor and Other Hyperkinetic Movements, 2016 Introduction: Writer's cramp is a specific focal hand dystonia causing abnormal posturing and tremor in the upper limb. The most popular medical intervention, botulinum neurotoxin type A (BoNT-A) therapy, is variably effective for 50–70% of patients ...
Mallory Jackman +6 more
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Rare functional missense variants in CACNA1H: What can we learn from Writer’s cramp? [PDF]
Molecular Brain, 2021 Writer’s cramp (WC) is a task-specific focal dystonia that occurs selectively in the hand and arm during writing. Previous studies have shown a role for genetics in the pathology of task-specific focal dystonia.
Miaozhen Huang +12 more
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Differential induction of Parieto-motor plasticity in writer's cramp and cervical dystonia [PDF]
Neurobiology of DiseaseObjectives: To investigate the plastic effects of parieto-motor (PAR-MOT) cortico-cortical paired associative paired stimulation (cc-PAS) in patients with two forms of focal dystonia, writer's cramp and cervical dystonia, compared to healthy volunteers ...
Hyun Joo Cho +10 more
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Motor network reorganization associated with rTMS-induced writing improvement in writer's cramp dystonia [PDF]
Brain StimulationBackground: Writer's cramp (WC) dystonia is an involuntary movement disorder with distributed abnormalities in the brain's motor network. Prior studies established the potential for repetitive transcranial magnetic stimulation (rTMS) to either premotor ...
Noreen Bukhari-Parlakturk +22 more
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