Results 131 to 140 of about 1,464 (252)

Effect of Botulinum Toxin on Sensori–Motor Integration in Movement Disorders: A Scoping Review

open access: yesToxins
Background: The primary effect of Botulinum toxin (BoNT) is to cause weakness in the injected muscles by inhibiting the release of acetyl choline from presynaptic nerve terminals.
Animesh Das, Mandar Jog
doaj   +1 more source

Familial writer's cramp: a clinical clue for inherited coenzyme Q10 deficiency. [PDF]

open access: yesNeurogenetics, 2021
Amprosi M   +8 more
europepmc   +1 more source

Allosteric DNAzyme‐Enabled Sensitive and Multiplex Detection of Biomarkers for Rapid Diagnosis of Urinary Tract Infections

open access: yesAdvanced Science, EarlyView.
A catalytic allosteric DNAzyme assay (SMART) is developed by engineering DNAzyme into a unimolecular biosensor, enabling highly sensitive and multiplex detection of small molecules and nucleic acids. SMART enables extraction‐free, one‐pot, one‐step, isothermal, and cost‐effective detection of biological markers, achieving >95% accuracy for rapid ...
Yanzhe Shen   +12 more
wiley   +1 more source

Task-Specific impairment of Motor Cortical Excitation and Inhibition in patients with writer’s cramp

open access: yes, 2005
Abnormalities in motor cortical excitation and inhibition have been reported in patients with writer's cramp, at rest and during muscle activation.
TINAZZI, Michele   +9 more
core   +1 more source

Light‐Switched Mesenchymal Stem Cells for In Situ Exosome Amplification in Craniofacial Bone Defect Reconstruction

open access: yesAdvanced Science, EarlyView.
Light‐switchable MSCs (MSC‐UCNPs) were constructed by intracellular incorporation of UCNPs. Upon 980 nm irradiation, UCNPs emitted localized ultraviolet light (365 nm), activating the ROS/HEXB/LAMP1 signaling pathway to suppress lysosome–multivesicular body fusion and thereby enhance exosome biogenesis. Embedded within an injectable hydrogel, MSC‐UCNPs
Tingting Wu   +7 more
wiley   +1 more source

Hemidystonia improved by intrathecal baclofen infusion therapy: A case report

open access: yesInterdisciplinary Neurosurgery
Intrathecal baclofen therapy (ITB) is a well-established treatment for limb spasticity due to brain and spinal cord disorders, and it is also indicated for dystonia, though mainly reported in generalized or pediatric cases.
Takashi Asahi   +6 more
doaj   +1 more source

“Membrane‐Guided” Repair Strategy: Precision Delivery of GGT1 Degrader for Targeted Repair and Regeneration of Spinal Cord Neurons

open access: yesAdvanced Science, EarlyView.
This study confirms that GGT1 is a key driver of neuronal ferroptosis following spinal cord injury. We developed NSCm@EA, a biomimetic delivery system coated with neural stem cell membranes, for precise delivery of enocyanin to injured neurons. By combining targeted delivery with ubiquitination degradation mechanisms, this system promotes MGRN1 ...
Tao Yang   +14 more
wiley   +1 more source

Increased volume and impaired function: the role of the basal ganglia in writer's cramp [PDF]

open access: yes, 2016
EINLEITUNG: Der Schreibkrampf ist eine aufgabenspezifische fokale Dystonieform der Hand. Die genaue Ätiologie ist bisher noch unklar. Ziel unserer Studie war die Untersuchung des Basalganglienkreislauf und des Cerebellums während Durchführung einer ...
Lindert, Julia Elisabeth
core  

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