Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Acute effects of foam rolling on jump performance and neuromuscular responses following resistance exercise. [PDF]
Rodoplu C +6 more
europepmc +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
LLM and CQL computable phenotypes for myocarditis adverse event feature and outcome determinations using patient FHIR data: a feasibility study. [PDF]
Gaspar FW +11 more
europepmc +1 more source
Pre-competitive anxiety, self-confidence, and technical-tactical performance in professional kickboxing athletes: differences between winners and defeated athletes. [PDF]
da Silva Duarte JDR +7 more
europepmc +1 more source
AI-assisted learning in exercise physiology: a quasi-experimental study using PhysioExercise GPT. [PDF]
Ribeiro Da Silva Junior R +9 more
europepmc +1 more source
From benchmarking to global leadership: Singapore's health sciences authority's journey to WHO maturity level 4 and WHO-Listed Authority status for medicines. [PDF]
Toh D +60 more
europepmc +1 more source

