Results 91 to 100 of about 2,359,590 (178)

Cancer vaccines: uses of HLA transgenic mice compared to genetically modified mice [PDF]

, 2008
Many tumor antigens have been identified that can be targeted by the immune system. Animal models that have been genetically modified to express human HLA molecules instead of their own MHC antigens have shown to be valuable in the discovery of peptides ...
McArdle, SE
core  

Beyond the Gut: The intratumoral microbiome's influence on tumorigenesis and treatment response

Cancer Communications, Volume 44, Issue 10, Page 1130-1167, October 2024.
Abstract The intratumoral microbiome (TM) refers to the microorganisms in the tumor tissues, including bacteria, fungi, viruses, and so on, and is distinct from the gut microbiome and circulating microbiota. TM is strongly associated with tumorigenesis, progression, metastasis, and response to therapy.
Hao Zhang, Li Fu, Xinwen Leiliang, Chunrun Qu, Wantao Wu, Rong Wen, Ning Huang, Qiuguang He, Quan Cheng, Guodong Liu, Yuan Cheng   +10 more
wiley   +1 more source

Approaches and methods to study wildlife cancer

Journal of Animal Ecology, Volume 93, Issue 10, Page 1410-1428, October 2024.
There are still a number of challenges in collecting cancer data from wild animals. This paper provides a review of currently available methods to detect and measure cancer in wild organisms as well as the methodological limitations to be overcome to develop approaches inspired by diagnostic techniques used in human medicine.
Mathieu Giraudeau, Orsolya Vincze, Sophie M. Dupont, Tuul Sepp, Ciara Baines, Jean‐Francois Lemaitre, Karin Lemberger, Sophie Gentès, Amy Boddy, Antoine M. Dujon, Georgina Bramwell, Valerie Harris, Beata Ujvari, Catherine Alix‐Panabières, Stephane Lair, David Sayag, Dalia A. Conde, Fernando Colchero, Tara M. Harrison, Samuel Pavard, Benjamin Padilla‐Morales, Damien Chevallier, Rodrigo Hamede, Benjamin Roche, Tamas Malkocs, Athena C. Aktipis, Carlo Maley, James DeGregori, Guillaume Le Loc’h, Frédéric Thomas   +29 more
wiley   +1 more source

Avian polyomavirus: a recent update [PDF]

, 2017
Avian polyomavirus disease is among the most common viral diseases of domesticated exotic birds as such in psittacine families. Caused by avian polyomavirus (APV) which possess a circular, double-stranded DNA which encodes for major structural virus ...
Abdul Razak, Mariatulqabtiah, Abu, Jalila, Mohd Padzil, Muhamad Faiz   +2 more
core  

Ependymal cells undergo astrocyte‐like reactivity in response to neuroinflammation

Journal of Neurochemistry, Volume 168, Issue 10, Page 3449-3466, October 2024.
Ependymal cells are unique glia that regulate local cerebrospinal fluid (CSF) microcirculation and form a dynamic interface between the brain and CSF. Here, we describe an unrecognized astrocyte‐like reactive transcriptomic profile that is assumed by ependymal cells in response to chronic neuroinflammation, that can be recapitulated following exposure ...
Adam M. R. Groh, Nina Caporicci‐Dinucci, Elia Afanasiev, Maxime Bigotte, Brianna Lu, Joshua Gertsvolf, Matthew D. Smith, Thomas Garton, Liam Callahan‐Martin, Alexis Allot, Dale J. Hatrock, Victoria Mamane, Sienna Drake, Huilin Tai, Jun Ding, Alyson E. Fournier, Catherine Larochelle, Peter A. Calabresi, Jo Anne Stratton   +18 more
wiley   +1 more source

WU and KI polyomavirus infections in pediatric hematology/oncology patients with acute respiratory tract illness

Journal of Clinical Virology, 2011
WU and KI polyomaviruses (PyV) were discovered in 2007 in respiratory tract samples in adults and children. Other polyomaviruses (BKPyV and JCPyV) have been associated with illness in immunocompromised patients, and some studies suggest a higher prevalence of WUPyV and KIPyV in this population.To determine whether a higher prevalence or viral load for ...
Rao, Suchitra, Garcea, Robert L., Robinson, Christine C., Simões, Eric A.F.   +3 more
openaire   +2 more sources

Correlation of histopathologic and dynamic tissue perfusion measurement findings in transplanted kidneys [PDF]

, 2013
BACKGROUND: Cortical perfusion of the renal transplant can be non-invasively assessed by color Doppler ultrasonography. We performed the Dynamic Tissue Perfusion Measurement (DTPM) of the transplant’s renal cortex using color Doppler ultrasonography ...
An-Hang Yang, Che-Chuan Loong, Hsin-Kai Wang, Thomas Scholbach, Tsai-Hong Wu   +4 more
core   +1 more source

WU and KI Polyomavirus Prevalence in Invasive Respiratory Samples From Transplant Recipients in Cantabria, Spain

Transplantation Proceedings, 2015
WU and KI polyomaviruses were discovered in 2007 in samples of respiratory secretions of children with acute respiratory symptoms. Seroepidemiologic studies have shown that these viruses are widely distributed throughout the world, but their incidence in Spain has not been determined.
Gozalo-Margüello, M., Agüero-Balbín, J., Martínez-Martínez, L.   +2 more
openaire   +2 more sources

Multiplex detection in tonsillar tissue of all known human polyomaviruses [PDF]

, 2017
Background: In the past few years, eleven new human viruses have joined the two previously known members JCPyV and BKPyV of the Polyomaviridae family, by virtue of molecular methods. Serology data suggest that infections with human polyomaviruses (HPyVs)
Aaltonen, Leena-Maija, Hedman, Klaus, Pyöriä, Lari, Ramqvist, Torbjorn, Sadeghi, Mohammadreza, Soderlund-Venermo, Maria, Toppinen, Mari, Wang, Yilin   +7 more
core   +1 more source

The interplay between viral-derived miRNAs and host immunity during infection [PDF]

, 2019
MicroRNAs are short non-coding RNAs that play a crucial role in the regulation of gene expression during cellular processes. The host-encoded miRNAs are known to modulate the antiviral defense during viral infection.
Ingle, Harshad, Kumar, Ashish, Kumar, Himanshu, Mishra, Richa   +3 more
core   +1 more source