Results 171 to 180 of about 4,897 (187)

Comparative mapping and genomic annotation of the bovine oncosuppressor gene WWOX.

Cytogenetic and genome research, 2009
WWOX (WW domain-containing oxidoreductase) is the gene mapping at FRA16D HSA16q23.1, the second most active common fragile site in the human genome. In this study we characterized at a detailed molecular level WWOX in the bovine genome. First, we sequenced cDNA from various tissues and obtained evidence in support of a 9-exon structure for the gene ...
Manera S, Bonfiglio S, Malusà A, Denis C, Boussaha M, RUSSO, VALERIA, ROPERTO, FRANCO PEPPINO, Perucatti A, Di Meo GP, Eggen A, Ferretti L.   +10 more
openaire   +6 more sources

WWOX, the tumour suppressor gene affected in multiple cancers.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2009
WWOX is a tumour suppressor gene affected in multiple cancers, especially in breast, prostate and ovary. This gene is located at the chromosomal area 16q23.3-24.1, which was identified as a common chromosomal fragile site FRA16D. WWOX turned out to possess tumour suppressor features despite the fact that the most basic (classical) way of tumour ...
U, Lewandowska, M, Zelazowski, K, Seta, M, Byczewska, E, Pluciennik, A K, Bednarek   +5 more
openaire   +1 more source

860 Fragile WWOX gene maintains genome integrity in fibroblasts

Journal of Investigative Dermatology, 2023
H. Cheng, Y. Chou, C. Hsu, L. Hsu
openaire   +1 more source

WWOX, the FRA16D gene, behaves as a suppressor of tumor growth.

Cancer research, 2001
We recently reported the cloning of WWOX, a gene that maps to the common fragile site FRA16D region in chromosome 16q23.3-24.1. It was observed that the genomic area spanned by WWOX is affected by chromosomal translocations and homozygous deletions.
A K, Bednarek, C L, Keck-Waggoner, R L, Daniel, K J, Laflin, P L, Bergsagel, K, Kiguchi, A J, Brenner, C M, Aldaz   +7 more
openaire   +1 more source

[Genotype and phenotype of WWOX gene related developmental and epileptic encephalopathy].

Zhonghua er ke za zhi = Chinese journal of pediatrics
Objective: To summarize the genotype and clinical phenotype of children with WWOX gene related developmental and epileptic encephalopathy (DEE). Methods: Case series studies. The clinical data of 12 children with WWOX gene related DEE who were admitted to the Neurological Department of Children's Medical Center, Peking University First Hospital from ...
T, Wang, M M, Cheng, W W, Liu, Q Z, Tan, C H, Liu, Y, Yang, X L, Yang, Y H, Zhang   +7 more
openaire   +1 more source

Deletion of the WWOX gene and frequent loss of its protein expression in human osteosarcoma

Cancer Letters, 2010
Jilong Yang, Da Yang, Kexin Chen
exaly  

Characterization of the tumor suppressor gene WWOX in primary human oral squamous cell carcinomas

International Journal of Cancer, 2006
C Marcelo Aldaz, Dawidson Assis Gomes, Marco Aurelio Romano-Silva   +2 more
exaly  

WWOX Gene and Gene Product: Tumor Suppression Through Specific Protein Interactions

Future Oncology, 2010
Zaidoun Salah, Rami Aqeilan, Frances Kay Huebner   +2 more
exaly  

The WWOX gene in brain development and pathology

Experimental Biology and Medicine, 2020
Katarzyna Kośla, Andrzej Bednarek
exaly  

ISID0860 - Fragile WWOX gene maintains genome integrity in fibroblasts

2023
openaire   +1 more source