Results 181 to 190 of about 163,168 (216)

X‐linked agammaglobulinemia complicated with endobronchial tuberculosis

Acta Paediatrica, 2010
AbstractAim:  We report a case of X‐linked agammaglobulinemia complicated with endobronchial tuberculosis.Methods:  We observed the patient’s clinical course and analysed his data retrospectively.Results: Interestingly, the T‐cell proliferation activity in this patient was intact, and the CD4‐positive T cells produced interferon gamma.
Chihiro, Kawakami, Akiko, Inoue, Kimitaka, Takitani, Hirokazu, Kanegane, Toshio, Miyawaki, Hiroshi, Tamai   +5 more
openaire   +2 more sources

Maternal germinal mosaicism of X‐linked agammaglobulinemia

American Journal of Medical Genetics, 2001
X-linked agammaglobulinemia (XLA) is an immunodeficiency caused by abnormalities in tyrosine kinase (BTK), and is characterized by a deficiency of peripheral blood B cells. We studied cytoplasmic expression of BTK protein and analyzed the BTK gene (BTK) in peripheral blood mononuclear cells from two siblings with XLA and additional family members ...
M, Sakamoto, H, Kanegane, H, Fujii, S, Tsukada, T, Miyawaki, N, Shinomiya   +5 more
openaire   +2 more sources

An International Survey of Allogeneic Hematopoietic Cell Transplantation for X-Linked Agammaglobulinemia

Journal of Clinical Immunology, 2023
Akira Nishimura, R. Uppuluri, Revathi Raj, V. Swaminathan, Yi-fei Cheng, R. Abu-Arja, Bin Fu, A. Laberko, M. Albert, F. Hauck, G. Bucciol, V. Bigley, S. Elcombe, G. Kharya, C. Pronk, Claudia Wehr, B. Neven, K. Warnatz, I. Meyts, T. Morio, A. Gennery, H. Kanegane   +21 more
semanticscholar   +1 more source

X-Linked Agammaglobulinemia and Bruton’s Tyrosine Kinase

1994
The genetic defect associated with human X-linked agammaglobulinemia (XLA) and murine X-linked immunodeficiency (XID) was recently identified as the deficiency of function of a new cytoplasmic tyrosine kinase called Bruton’s tyrosine kinase (Btk)1,2,3,4. The phenotypes associated with these immunodeficiencies indicate that Btk plays a crucial role in B
S, Tsukada, O N, Witte
openaire   +2 more sources

X-linked agammaglobulinemia

2023
Domenico Nicoletti, Yuranga Weerakkody, Henry Knipe   +2 more
openaire   +1 more source

Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia

Cell, 1993
S. Tsukada, D. Saffran, D. Rawlings, O. Parolini, R. Allen, I. Klisak, R. Sparkes, H. Kubagawa, T. Mohandas, S. Quan, J. Belmont, M. Cooper, M. Conley, O. Witte   +13 more
semanticscholar   +1 more source

Retrospective study of 98 patients with X-linked agammaglobulinemia complicated with arthritis

Clinical Rheumatology, 2022
Qing Ran, Ya-wen Li, Chen Huan, Zhang Yu, Y. An, Xue-mei Tang, Xiaodong Zhao, Zhi-yong Zhang   +7 more
semanticscholar   +1 more source

Atypical X-Linked Agammaglobulinemia

New England Journal of Medicine, 1994
S J, Kornfeld, R A, Good, G W, Litman
openaire   +3 more sources

Agammaglobulinemia: from X-linked to Autosomal Forms of Disease

Clinical Reviews in Allergy and Immunology, 2021
Melissa Cardenas-Morales
exaly  

Atypical X-linked agammaglobulinemia - reply

1994
To the Editor: The letter of Kornfeld et al. raises two separate questions: Do some patients with mild hypogammaglobulinemia have defects in the same gene as patients with typical X-linked agammaglobulinemia? Can you predict the clinical phenotype of X-linked agammaglobulinemia on the basis of the site of the Btk mutation?
Parolini, Ornella, Rohrer, J, Conley, Me
openaire   +1 more source