Results 11 to 20 of about 161,849 (206)

Immune Thrombocytopenia in an Adult With X‐linked Agammaglobulinemia: A Case Report [PDF]

eJHaem
In patients with X‐linked agammaglobulinemia (XLA), serum immunoglobulins are almost completely lacking. The prevalence of autoimmune diseases is low in XLA compared with other primary immunodeficiency diseases because antibodies are absent in XLA ...
Takeaki Matsunaga, Ken Naganuma, Noriko Tanabe, Yoshiko Mori, Marino Nagata, Shuji Momose, Yasushi Kubota   +6 more
doaj   +3 more sources

Naïve Regulatory T Cell Subset Is Altered in X-Linked Agammaglobulinemia [PDF]

Frontiers in Immunology, 2021
The interplay between T- and B-cell compartments during naïve, effector and memory T cell maturation is critical for a balanced immune response. Primary B-cell immunodeficiency arising from X-linked agammaglobulinemia (XLA) offers a model to explore B ...
Pavel V. Shelyakin, Ksenia R. Lupyr, Ksenia R. Lupyr, Evgeny S. Egorov, Ilya A. Kofiadi, Dmitriy B. Staroverov, Dmitriy B. Staroverov, Sofya A. Kasatskaya, Sofya A. Kasatskaya, Sofya A. Kasatskaya, Valeriia V. Kriukova, Valeriia V. Kriukova, Irina A. Shagina, Irina A. Shagina, Ekaterina M. Merzlyak, Ekaterina M. Merzlyak, Tatiana O. Nakonechnaya, Elena A. Latysheva, Irina A. Manto, Musa R. Khaitov, Sergey A. Lukyanov, Dmitriy M. Chudakov, Dmitriy M. Chudakov, Dmitriy M. Chudakov, Olga V. Britanova   +24 more
doaj   +3 more sources

Severe Tick-Borne Encephalitis (TBE) in a Patient with X-Linked Agammaglobulinemia; Treatment with TBE Virus IgG Positive Plasma, Clinical Outcome and T Cell Responses. [PDF]

J Clin Immunol
Purpose A patient with X-linked agammaglobulinemia (XLA) and severe tick-borne encephalitis (TBE) was treated with TBE virus (TBEV) IgG positive plasma.
Hedin W, Bergman P, Akhirunessa M, Söderholm S, Buggert M, Granberg T, Gredmark-Russ S, Smith CIE, Pettke A, Wahren Borgström E.   +9 more
europepmc   +3 more sources

Clinical and genetic findings in two siblings with X-Linked agammaglobulinemia and bronchiolitis obliterans: a case report [PDF]

BMC Pediatrics, 2022
Background X-linked agammaglobulinemia (XLA) is an Inborn Errors of Immunity (IEI) characterized by pan-hypogammaglobulinemia and low numbers of B lymphocytes due to mutations in BTK gene.
Ronaldo da Silva Francisco Junior, Guilherme Loss de Morais, Joseane Biso de Carvalho, Cristina dos Santos Ferreira, Alexandra Lehmkuhl Gerber, Ana Paula de C Guimarães, Flávia Anisio Amendola, Fernanda Pinto-Mariz, Zilton Farias Meira de Vasconcelos, Ekaterini Simões Goudouris, Ana Tereza Ribeiro de Vasconcelos   +10 more
doaj   +3 more sources

A Registry Study of 240 Patients with X-Linked Agammaglobulinemia Living in the USA. [PDF]

J Clin Immunol, 2023
Purpose To understand the natural history and clinical outcomes for patients with X-linked agammaglobulinemia (XLA) in the United States utilizing the United States Immunodeficiency Network (USIDNET) patient registry.
Hernandez-Trujillo V, Zhou C, Scalchunes C, Ochs HD, Sullivan KE, Cunningham-Rundles C, Fuleihan RL, Bonilla FA, Petrovic A, Rawlings DJ, de la Morena MT.   +10 more
europepmc   +2 more sources

BTKbase, Bruton Tyrosine Kinase Variant Database in X-Linked Agammaglobulinemia: Looking Back and Ahead. [PDF]

Hum Mutat, 2023
BTKbase is an international database for disease-causing variants in Bruton tyrosine kinase (BTK) leading to X-linked agammaglobulinemia (XLA), a rare primary immunodeficiency of antibody production.
Schaafsma GCP, Väliaho J, Wang Q, Berglöf A, Zain R, Smith CIE, Vihinen M.   +6 more
europepmc   +2 more sources

Carbapenem resistant Campylobacter jejuni bacteremia in a Bruton's X-linked agammaglobulinemia patient. [PDF]

Eur J Clin Microbiol Infect Dis
Immunocompromised patients are prone to recurrent Campylobacter infections. We report a case of recurrent multi-drug resistant Campylobactor jejuni bloodstream infections in a Bruton’s X-linked agammaglobulinemia patient with prolonged ertapenem ...
Zhuo R, Younes RL, Ward K, Yang S.
europepmc   +2 more sources

Chronic Diarrhea with Villous Blunting of the Small Intestine Under Capsule Endoscopy in Common Variable Immunodeficiency and X-Linked Agammaglobulinemia: A Case Series. [PDF]

J Asthma Allergy, 2023
Introduction Primary immunodeficiencies (PIDs) are a heterogeneous group of disorders, common variable immunodeficiency disorder (CVID) and X-linked agammaglobulinemia (XLA) are PIDs related to B-cell defect, characterized by reduced levels of ...
Deng F, Wang H, Wang X.
europepmc   +2 more sources

X-Linked Agammaglobulinemia: Infection Frequency and Infection-Related Mortality in the USIDNET Registry. [PDF]

J Clin Immunol, 2022
X-linked agammaglobulinemia (XLA) is a primary immunodeficiency disorder caused by mutations in the Bruton tyrosine kinase (BTK) gene leading to B lymphocyte deficiency and susceptibility to infection.
O'Toole D, Groth D, Wright H, Bonilla FA, Fuleihan RL, Cunningham-Rundles C, Sullivan KE, Ochs HD, Marsh R, Feuille E.   +9 more
europepmc   +2 more sources

Autism in a Child With X-linked Agammaglobulinemia. [PDF]

Cureus, 2022
A growing evidence base has implicated immune dysfunction in the etiology of some cases of autism spectrum disorder. The precise relationship between immune disorders and autism spectrum disorder remains unclear. Herein we report a 14-year-old-male with agammaglobulinemia, who was diagnosed with autism spectrum disorder, and who has received exogenous ...
Bied A, Njuguna S, Satodiya R.
europepmc   +4 more sources