Results 31 to 40 of about 7,233,987 (192)

X-Linked Hypophosphatemia: Does Targeted Therapy Modify Dental Impairment?

, 2023
X-linked hypophosphatemia is a rare, hereditary disorder that significant influences teeth and alveolar bone. The first clinical sign leading to the diagnosis of X-linked hypophosphatemia is often dental impairment with dental abscesses and dentin ...
Ina Dewenter, Maximilian Kollmuss, Steybe, David, Anusha Abdullah, Fegg, Florian Nepomuk, Otto, Sven, Philipp Poxleitner, Wenko Smolka, Florian Nepomuk Fegg, David Steybe, Dewenter, Ina, Kollmuss, Maximilian, Leonard Simon Brandenburg, Obermeier, Katharina Theresa, Wuersching, Sabina Noreen, Brandenburg, Leonard Simon, Smolka, Wenko, Abdullah, Anusha, Sven Otto, Sabina Noreen Wuersching, Poxleitner, Philipp, Katharina Theresa Obermeier   +21 more
core   +1 more source

Bone Age Delay in X-linked Hypophosphatemia. [PDF]

J Endocr Soc
Abstract Context Bone age (BA) assessment and prediction of adult height (AdHt) has not been well studied in children with X-linked hypophosphatemia (XLH). Objective To assess BA and its utility in height prediction ...
Soto J, Patki RA, Ehrlich LJ, Borkar R, León A, Olear EA, Silva CT, Carpenter TO.   +7 more
europepmc   +3 more sources

Dental Manifestations and Oral Management of X-Linked Hypophosphatemia

Endocrines, 2022
X-linked hypophosphatemia (XLH) is the most common genetic form of rickets and osteomalacia and is characterized by growth retardation, deformities of the lower limbs, and bone and muscular pain.
Rena Okawa, Kazuhiko Nakano
doaj   +1 more source

Effect of four monthly doses of a human monoclonal anti-FGF23 antibody (KRN23) on quality of life in X-linked hypophosphatemia

Bone Reports, 2016
X-linked hypophosphatemia (XLH) is characterized by lower extremity deformities that lead to bone and/or joint pain that result from decreased renal tubular reabsorption leading to hypophosphatemia caused by elevated levels of fibroblast growth factor 23
Mary D. Ruppe, Xiaoping Zhang, Erik A. Imel, Thomas J. Weber, Mark A. Klausner, Takahiro Ito, Maria Vergeire, Jeffrey S. Humphrey, Francis H. Glorieux, Anthony A. Portale, Karl Insogna, Munro Peacock, Thomas O. Carpenter   +12 more
doaj   +1 more source

Burosumab and Dental Abscesses in Children With X‐Linked Hypophosphatemia

JBMR Plus, 2022
X‐linked hypophosphatemia (XLH) is a rare genetic disorder that disrupts skeletal and dental mineralization. In addition to rickets in children, XLH patients also have frequent spontaneous dental abscesses that increase the risk of tooth loss and may ...
Margaux Gadion, Agathe Hervé, Julia Herrou, Anya Rothenbuhler, Violaine Smail‐Faugeron, Frédéric Courson, Agnès Linglart, Catherine Chaussain, Martin Biosse Duplan   +8 more
doaj   +1 more source

X-linked hypophosphatemic rickets: from diagnosis to management [PDF]

Clinical and Experimental Pediatrics
X-linked hypophosphatemia (XLH), the most common cause of hypophosphatemic rickets, affects one in every 20,000 people. Although conventional therapy for XLH was introduced approximately 4 decades ago, the temporary replacement of oral phosphate salts ...
Eujin Park, Hee Gyung Kang
doaj   +1 more source

Joint replacement in X-linked hypophosphatemia [PDF]

Journal of Orthopaedics, 2019
X-linked hypophosphatemia (XLH) is associated with a pervasive, severe degenerative osteoarthritis. We conducted a retrospective chart review/patient survey using the Knee or Hip Osteoarthritis Outcome Score Physical Function Short Form. Fourteen total knee arthroplasties and 7 total hip arthroplasties among 11 patients were included.
Emily S, Mills, Louis, Iorio, Richard S, Feinn, Kevin M, Duignan, Carolyn M, Macica   +4 more
openaire   +2 more sources

Additional file 1 of Growth hormone treatment improves final height in children with X-linked hypophosphatemia

, 2022
Additional file 1: Table S1 Description of children with X-linked hypophosphatemia treated with rhGH and with or without aGnRH. Table S2 Description of height changes in children with X-linked hypophosphatemia given rhGH through follow-up, stratified by ...
Brigitte Mignot (3520817), Catherine Chaussain (381332), Julia André (7500170), Anne-Sophie Lambert (3510560), Claire Bardet (381318), Jean-Pierre Salles (825652), Volha V. Zhukouskaya (15250244), Agnès Linglart (381330), Anya Rothenbuhler (4537882)   +8 more
core   +1 more source

Calcitonin Administration in X-Linked Hypophosphatemia [PDF]

New England Journal of Medicine, 2011
To the Editor: In X-linked hypophosphatemia, phosphate wasting results from increased circulating levels of fibroblast growth factor 23 (FGF-23).1 Administration of calcitonin to a patient with onc...
Eva S, Liu, Thomas O, Carpenter, Caren M, Gundberg, Christine A, Simpson, Karl L, Insogna   +4 more
openaire   +2 more sources

Growth curves for children with X-linked hypophosphatemia [PDF]

Yearbook of Paediatric Endocrinology, 2019
Abstract Context We characterized linear growth in infants and children with X-linked hypophosphatemia (XLH). Objective Provide linear growth curves for children with XLH from birth to early adolescence.
Meng Mao, Thomas O Carpenter, Michael P Whyte, Alison Skrinar, Chao-Yin Chen, Javier San Martin, Alan D Rogol   +6 more
openaire   +2 more sources