Results 51 to 60 of about 7,233,987 (192)
Phenotypic characterization of X-linked hypophosphatemia in pediatric Spanish population
Orphanet Journal of Rare Diseases, 2021 Background X-linked hypophosphatemia (XLH) is a hereditary rare disease caused by loss-of-function mutations in PHEX gene leading tohypophosphatemia and high renal loss of phosphate.
Enrique Rodríguez-Rubio +21 more
doaj +1 more source
RADIOLOGICAL FINDINGS IN X-LINKED HYPOPHOSPHATEMIA
, 2020 Radiological findings in X-linked hypophosphatemia are similar to, albeit less severe than, nutritional rickets. Loss of distinctness of the zone of provisional calcification, widening of the growth plate first in the long axis, followed by widening in ...
core +1 more source
, 2020 Supplemental material, DS_10.1177_0022034520901719 for Dentoalveolar Defects in the Hyp Mouse Model of X-linked Hypophosphatemia by H. Zhang, M.B. Chavez, T.N. Kolli, M.H. Tan, H. Fong, E.Y. Chu, Y. Li, X. Ren, K. Watanabe, D.G. Kim and B.L.
D.G. Kim (8359554) +10 more
core +1 more source
Dental health of patients with X-linked hypophosphatemia: A controlled study
Frontiers in Oral Health, 2023 ObjectiveThe present study compared the dental health of patients with X-linked hypophosphatemia (XLH) with healthy age- and gender-matched controls to increase our knowledge of the impact of XLH on oral health.Materials and methodsTwenty-two adult ...
Amila Larsson +10 more
doaj +1 more source
Mesothelin as Biomarker and Therapeutic Target for Immunotherapy in Cancer
MedComm, Volume 7, Issue 10, October 2026.Mesothelin overexpression activate important pathways like nuclear factor k‐light‐chain‐enhancer of activated B cells (NF‐κB) and interleukin‐6 (IL‐6). This in turn causes numerous cancers, such as pancreatic and ovarian cancers. MSLN‐targeting immunotherapies, like monoclonal antibodies, have shown efficacy.
Manoj Kumar Gupta +2 more
wiley +1 more source
Seminars in nephrology, 1989 X-linked hypophosphatemia is a common cause of metabolic rickets in children in this country. The gene defect is localized to the Xp22 region in man. Research into this disorder has been enhanced by the discovery of a mutant gene named Hyp on the X chromosome of mice that produces a syndrome similar to the human disease.
R A, Meyer, W F, Conway, J C, Chan
openaire +4 more sources
Iron and Other Metal Ions in Human Health and Disease
MedComm, Volume 7, Issue 10, October 2026.Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
wiley +1 more source
, 2023 X-linked hypophosphatemia (XLH) is a rare genetic disease, characterized by renal phosphate wasting and complex musculoskeletal manifestations including decreased physical performance. Objective is to characterize muscular deficits in patients with XLH
Jochen Zange +17 more
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Approach to a Child with Hypophosphatemia
BiomoleculesHypophosphatemia is a rare ion disorder in children, but it carries the risk of serious clinical sequelae in tissues and organs with high energy requirements, such as bone tissue.
Agnieszka Antonowicz +3 more
doaj +1 more source
Nucleic Acids as Emerging Regulators of Calcium Phosphate Biomineralization
The FASEB Journal, Volume 40, Issue 17, 15 September 2026.Calcium phosphate biomineralization has traditionally been considered a protein‐regulated process. This review highlights the emerging role of nucleic acids, which interact with mineral phases through adsorption, coprecipitation, and templating, thereby influencing crystal nucleation and growth.
Fanny Duhalde +2 more
wiley +1 more source