Results 161 to 170 of about 6,581,018 (264)

A Modular Synthesis of C5‐Sulfenyl Thiazoles via an Intermolecular Pummerer Rearrangement: An Underexplored Scaffold for Medicinal Chemistry

Angewandte Chemie, EarlyView.
Modular access to underexplored C5‐sulfenyl thiazoles via an intermolecular Pummerer rearrangement is reported. The methodology exhibits a broad functional group tolerance enabling the seamless design of trisubstituted thiazole cores bearing a sulfur handle for further elaboration.
Joe L. Smy, Theo C. Webb, Barnaby W. Greenland, S. Mark Roe, John Spencer, Storm Hassell‐Hart   +5 more
wiley   +2 more sources

Using X-ray Crystallography and 1,n-ADEQUATE NMR to Revise the Structures of Highly Substituted Aromatic Natural Products: The Absolute Configuration of Formicamycin Congeners. [PDF]

J Nat Prod
Hems ES, Wright JA, Nepogodiev SA, Devine R, Arnold CJ, Hughes DL, Mundy JEA, Eltschkner S, Lawson DM, Hutchings MI, Wilkinson B.   +10 more
europepmc   +1 more source

Cobalt‐Catalyzed [2σ+2π] Cycloaddition via Site‐Selective Capture of Bicyclobutane Diradical

Angewandte Chemie, EarlyView.
We report a Co(II)‐catalyzed strategy that combines thermal activation of bicyclo[1.1.0]butane (BCBs) with site‐selective radical capture to furnish head‐to‐head fused bicyclo[2.1.1]hexanes via [2σ+2π] cycloaddition with indoles. Detailed mechanistic studies (31P NMR, EPR, CV, and DFT) support the catalytic pathway, while phosphine‐oxide trapping and X‐
Tanmayee Nanda, Alexander Umanzor, Julia Gartzke, Jeremy T. Maddigan‐Wyatt, Philipp Thielert, Stefan Weber, Sabine Richert, Shuming Chen, Daniel B. Werz   +8 more
wiley   +2 more sources

Breaking barriers: transitioning from X-ray crystallography to cryo-EM for structural studies. [PDF]

Acta Crystallogr D Struct Biol
Zafar H, Malone KL, Singh AK, Cianfrocco MA, Glass KC.   +4 more
europepmc   +1 more source

A study of the organometallic chemistry of aluminium, gallium and idium [PDF]

This thesis describes a study of several aspects of the organometallic chemistry of aluminium, gallium and indium. A study has been carried out on the products obtained from the reactions of trimethyl- and triethyl-metal derivatives of aluminium ...
Phillips, Paul Richard
core  

Induction of Methuosis in Breast Cancer Stem Cells by a Cobalt(III) Complex Evokes Immunotherapeutic Response

Angewandte Chemie, EarlyView.
Cancer stem cells (CSCs) drive metastasis, relapse and resist conventional apoptosis‐inducing chemotherapies. We report a cobalt(III)‐cyclam complex with pyrene and diflunisal moieties that reduces the viability of breast CSCs at low micromolar concentrations.
Jiaxin Fang, Sijie Wen, Xiao Feng, Hao Ren, Kuldip Singh, Haihua Xiao, Lingpu Zhang, Kogularamanan Suntharalingam   +7 more
wiley   +2 more sources

Crystal structure of 2,5-di-5-benzyl(1-thia-3,4-diazacyclopenta-2,5-diene), C16H14N2S3

Zeitschrift für Kristallographie - New Crystal Structures, 2000
Tarafder M. T. H., Saravanan N., Crouse K. A., Yamin B. M., Raj S. S. S., Razak I. A., Fun H.-K.   +6 more
doaj   +1 more source

Infrared protein crystallography [PDF]

, 2011
Ravelli, Raimond B. G., Sage, J. Timothy, McGeehan, John, Zhang, Yunbin, Van Thor, Jasper J., Weik, Martin   +5 more
core   +1 more source

TADF‐Active Tetrazole Luminophores for Visible‐Light Functionalization of Nanoparticles and Surfaces

Angewandte Chemie, EarlyView.
A series of tetrazoles are reported that undergo 1,3‐dipolar cycloadditions with alkene and alkyne substrates, generating (dihydro)pyrazole products that exhibit thermally activated delayed fluorescence (TADF). The “photo‐click” reactivity of these tetrazoles is leveraged to functionalize nanoparticles and surfaces with TADF‐active chromophores ...
Ryoga Hojo, Katrina Bergmann, Siyuan L. Xie, Connor S. Durfy, William L. Primrose, Athan T. Gogoulis, Seja A. Elgadi, Mitchell J. Demchuk, Thomas Kalab, Peiqi Hu, Eva M. Nichols, Zachary M. Hudson   +11 more
wiley   +2 more sources

Crystal structure of 2-S-benzyl-5-phenyl-1-(1-thia-3,4-diazacyclopenta-2,4-diene), C15H12N2S2

Zeitschrift für Kristallographie - New Crystal Structures, 2000
Tarafder M. T. H., Azahari K., Crouse K. A., Yamin B. M., Raj S. S. S., Razak I. A., Fun H.-K.   +6 more
doaj   +1 more source