Results 51 to 60 of about 265,473 (286)

Wavefront sensing at X-ray free-electron lasers

open access: yesJournal of Synchrotron Radiation, 2019
Here a direct comparison is made between various X-ray wavefront sensing methods with application to optics alignment and focus characterization at X-ray free-electron lasers (XFELs). Focus optimization at XFEL beamlines presents unique challenges due to high peak powers as well as beam pointing instability, meaning that techniques capable of single ...
Seaberg, Matthew   +22 more
openaire   +3 more sources

High efficiency, multiterawatt x-ray free electron lasers [PDF]

open access: yesPhysical Review Accelerators and Beams, 2016
We study high efficiency, multi-terawatt peak power, few angstrom wavelength, X-ray Free Electron Lasers (X-ray FELs). To obtain these characteristics we consider an optimized undulator design: superconducting, helical, with short period and built-in strong focusing.
C. Emma, K. Fang, J. Wu, C. Pellegrini
openaire   +3 more sources

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Hard x-ray or gamma ray laser by a dense electron beam

open access: yes, 2012
A coherent x-ray or gamma ray can be created from a dense electron beam propagating through an intense laser undulator. It is analyzed by using the Landau damping theory which suits better than the conventional linear analysis for the free electron laser,
Moon, S. J., Son, S.
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Optical Shaping of X-Ray Free-Electron Lasers

open access: yesPhysical Review Letters, 2016
In this Letter we report the experimental demonstration of a new temporal shaping technique for x-ray free-electron lasers (FELs). This technique is based on the use of a spectrally shaped infrared (IR) laser and allows optical control of the x-ray generation process.
A, Marinelli   +11 more
openaire   +3 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

A pipeline for megahertz X-ray photon correlation spectroscopy on soft matter samples at the MID instrument of European XFEL

open access: yesJournal of Synchrotron Radiation
In this article, we present the experimental protocol and data-processing framework for megahertz X-ray Photon Correlation Spectroscopy (MHz-XPCS) experiments on soft matter samples implemented at the Materials Imaging and Dynamics (MID) instrument of ...
Aliaksandr Leonau   +30 more
doaj   +1 more source

Imaging Molecular Structure through Femtosecond Photoelectron Diffraction on Aligned and Oriented Gas-Phase Molecules [PDF]

open access: yes, 2014
This paper gives an account of our progress towards performing femtosecond time-resolved photoelectron diffraction on gas-phase molecules in a pump-probe setup combining optical lasers and an X-ray Free-Electron Laser.
Adolph, Marcus   +52 more
core   +3 more sources

Thermoreflectance Detection of Point Defects Resulting from Focused Ion Beam Milling

open access: yesAdvanced Engineering Materials, EarlyView.
Focused ion beam (FIB) milling is a common tool for nanoscale material processing, however irradiation damage, redeposition, and contamination can occur. We use several characterization tools to show FIB‐induced effects beyond 1 mm from the milled area.
Thomas W. Pfeifer   +3 more
wiley   +1 more source

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