Results 81 to 90 of about 1,474,810 (297)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Comparative Statistical Analysis of Prompt and Afterglow X-Ray Flares in Gamma-Ray Bursts: Insights into Extended Central Engine Activity

open access: yesThe Astrophysical Journal
Gamma-ray bursts (GRBs) are the most energetic phenomena in the Universe, characterized by prompt gamma-ray emission followed by multiwavelength afterglows.
Yinuo Ma, He Gao
doaj   +1 more source

Swift X-Ray Observations of Classical Novae. II. The Super Soft Source sample

open access: yes, 2011
The Swift GRB satellite is an excellent facility for studying novae. Its rapid response time and sensitive X-ray detector provides an unparalleled opportunity to investigate the previously poorly sampled evolution of novae in the X-ray regime. This paper
A. P. Beardmore   +235 more
core   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

X-Ray Phase Analysis Of Nitrided Layers Of X2CrNiMo17-12-2 Austenitic Steel

open access: yesArchives of Metallurgy and Materials, 2015
This work presents the results of diffraction analyses carried out using X-ray phase analyses (XRD and GIXRD) of nitrided layers of X2CrNiMo17-12-2 austenitic steel.
Frączek T., Olejnik M., Pilarska M.
doaj   +1 more source

High-Resolution X-Ray Spectroscopy of the Accretion Disk Corona Source 4U 1822-37

open access: yes, 2001
We present a preliminary analysis of the X-ray spectrum of the accretion disk corona source, 4U 1822-37, obtained with the High Energy Transmission Grating Spectrometer onboard the Chandra X-ray Observatory.
Duane A. Liedahl   +7 more
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Theoretical and experimental analysis of the modulated phase grating X-ray interferometer

open access: yesScientific Reports
X-ray grating interferometry allows for the simultaneous acquisition of attenuation, differential-phase contrast, and dark-field images, resulting from X-ray attenuation, refraction, and small-angle scattering, respectively.
Hunter Meyer   +11 more
doaj   +1 more source

Phase Resolved X-Ray Spectral Analysis of Intermediate Polars EX Hya and FO Aqr

open access: yesEPJ Web of Conferences, 2014
Intermediate Polars (IPs): EX Hya and FO Aqr whichs are a subclass of Cataclysmic Variables (CVs) where a white dwarf with magnetic field strength of about 1-10MG accretes material from a main sequence companion through a truncated disc.
Pekön Yakup, Balman Şlölen
doaj   +1 more source

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