Results 21 to 30 of about 10,186,878 (261)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Gamma-ray bursts during neutron star formation. Gamma-ray bursts and transient X-ray sources [PDF]
Discussions are presented of the associations between cosmic gamma ray bursts and transient X-ray sources, and the release of gravitational binding energy during the formation of neutron stars.
Cohen, J. M., Desai, U. D., Holt, S. S.
core
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
The properties of discrete X-ray sources in star-forming galaxies [PDF]
Observations of starburst galaxies have revealed a large number of point-like X-ray sources located within these systems, including active galactic nuclei (AGN), X-ray binaries (XRBs), and utraluminous X-ray sources (ULXs).
JACKSON, FLOYD,EMMANUEL
core
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Very high energy cosmic gamma rays from radio and x-ray pulsars [PDF]
This thesis is concerned with the detection of very high energy cosmic gamma-rays from isolated pulsars and X-ray binary sources using the atmospheric Cerenkov technique. A general introduction to gamma ray detection techniques is followed by adscription
Chadwick, P.M, Chadwick, Mary Paula
core
A low-cost X-ray-transparent experimental cell for synchrotron-based X-ray microtomography studies under geological reservoir conditions [PDF]
A new modular X-ray-transparent experimental cell enables tomographic investigations of fluid rock interaction under natural reservoir conditions (confining pressure up to 20 MPa, pore fluid pressure up to 15 MPa, temperature ranging from 296 to 473 K ...
Zhu, Wenlu +13 more
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Progress on laser-driven X-ray sources at ELI Beamlines
Three main paths are being developed within the ELI research program for transforming driving laser pulses into bursts of bright short wavelength radiation: high-order harmonic generation in gases, plasma X-ray sources and sources based on relativistic ...
Hort O. +6 more
core +1 more source

