Results 41 to 50 of about 214,668 (294)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Transitional Dynamics: Unveiling the Coexistence and Interplay of Type B and Type C Quasiperiodic Oscillations in MAXI J1348-630

open access: yesThe Astrophysical Journal
Based on broadband timing analysis of Insight-HXMT and Neutron Star Interior Composition Explorer data from the 2019 outburst of the black hole X-ray binary MAXI J1348-630, we report the detection of the coexistence and competitive interplay between Type
Xin-Lei Wang   +5 more
doaj   +1 more source

Hard X-ray observations of transient X-ray source GS 1843+00 [PDF]

open access: yesMonthly Notices of the Royal Astronomical Society, 1999
The transient X-ray source GS 1843+00 was observed in the hard X-ray region from 20 to 200 keV, during its flare mode in 1997 March. Spectral measurements were made during a balloon flight experiment using a newly designed large-area scintillation counter telescope. The present observations correspond to the mid-point of the transient phase.
openaire   +1 more source

DISCOVERY OF MILLIHERTZ X-RAY OSCILLATIONS IN A TRANSIENT ULTRALUMINOUS X-RAY SOURCE IN M82 [PDF]

open access: yesThe Astrophysical Journal, 2010
5 pages, 1 figure, accepted for publication in The Astrophysical Journal ...
Feng, Hua, Rao, Fengyun, Kaaret, Philip
openaire   +2 more sources

Outbursts, State Transitions, and Periodicities Observed with the RXTE All-Sky Monitor

open access: yes, 1998
Results from the All-Sky Monitor (ASM) on the Rossi X-ray Timing Explorer are reviewed. A number of recurrent transient sources have been detected, while only a few previously unreported sources have been discovered.
Alan M. Levine   +17 more
core   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Constraints on Relativistic Jets from the Fast X-Ray Transient 210423 Using Prompt Radio Follow-up Observations

open access: yesThe Astrophysical Journal
Fast X-ray transients (FXTs) are a new observational class of phenomena with no clear physical origin. This is at least partially a consequence of limited multiwavelength follow-up of this class of transients in real time.
Dina Ibrahimzade   +18 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Delayed X-Ray Brightening Accompanied by Variable Ionized Absorption Following a Tidal Disruption Event

open access: yesThe Astrophysical Journal
Supermassive black holes can experience super-Eddington peak mass fallback rates following the tidal disruption of a star. The theoretical expectation is that part of the infalling material is expelled by means of an accretion disk wind, whose ...
T. Wevers   +6 more
doaj   +1 more source

The XMM-Newton survey of the Small Magellanic Cloud: XMMUJ005011.2-730026 = SXP214, a Be/X-ray binary pulsar [PDF]

open access: yes, 2011
In the course of the XMM-Newton survey of the Small Magellanic Cloud (SMC), a region to the east of the emission nebula N19 was observed in November 2009.
A. Tiengo   +46 more
core   +2 more sources

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