Results 51 to 60 of about 9,734,716 (302)

Reanalysis of the X-Ray-burst-associated FRB 200428 with Insight-HXMT Observations

The Astrophysical Journal, 2023
A double-peak X-ray burst from the Galactic magnetar SGR J1935+2154 was discovered to be associated with the two radio pulses of FRB 200428 separated by 28.97 ± 0.02 ms.
M. Y. Ge, C. Z. Liu, S. N. Zhang, F. J. Lu, Z. Zhang, Z. Chang, Y. L. Tuo, X. B. Li, C. K. Li, S. L. Xiong, C. Cai, X. F. Li, R. Zhang, Z. G. Dai, J. L. Qu, L. M. Song, S. Zhang, L. J. Wang   +17 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Constraints on Relativistic Jets from the Fast X-Ray Transient 210423 Using Prompt Radio Follow-up Observations

The Astrophysical Journal
Fast X-ray transients (FXTs) are a new observational class of phenomena with no clear physical origin. This is at least partially a consequence of limited multiwavelength follow-up of this class of transients in real time.
Dina Ibrahimzade, R. Margutti, J. S. Bright, P. Blanchard, K. Paterson, D. Lin, H. Sears, A. Polzin, I. Andreoni, G. Schroeder, K. D. Alexander, E. Berger, D. L. Coppejans, A. Hajela, J. Irwin, T. Laskar, B. D. Metzger, J. C. Rastinejad, L. Rhodes   +18 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

On the Nature of Einstein Probe Transient EP250916a: Insights from X-Ray, Optical, and Radio Observations

The Astrophysical Journal
We report multiwavelength studies of the transient EP250916a, detected by the Einstein Probe on 2025 September 16. Located at low Galactic latitude, the source exhibited a rapid X-ray brightening, reaching an unabsorbed 0.5–10 keV flux of (6.4 ± 0.1 ...
Gaurava K. Jaisawal, Giulia Illiano, Francesco Carotenuto, Astrid L. Bouquin, David M. Russell, Giorgos Leloudas, Andrea Sanna, Dalya Akl, Rob Fender, Sara Motta   +9 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Laboratory implementation of edge illumination X-ray phase-contrast imaging with energy-resolved detectors [PDF]

, 2015
Edge illumination (EI) X-ray phase-contrast imaging (XPCI) has potential for applications in different fields of research, including materials science, non-destructive industrial testing, small-animal imaging, and medical imaging.
A. Olivo, De Ruvo, L, Endrizzi, M., Kallon, G, SPANDRE, GLORIA, G. Spandre, Vincenzi, A, Kallon, G., A. Brez, Hagen, C. K., Olivo, A, L. De Ruvo, Basta, D, P. C. Diemoz, F. A. Vittoria, Hagen, CK, Olivo, A., C. K. Hagen, Spandre, G, Brez, A., M. Marenzana, Brez, A, DELOGU, PASQUALE, Vittoria, F. A., Marenzana, M., Bellazzini, R, Diemoz, P. C., Vincenzi, A., BELLAZZINI, RONALDO, A. Vincenzi, D. Basta, M. Endrizzi, G. Kallon, R. Bellazzini, Diemoz, PC, Vittoria, FA, Delogu, P, Endrizzi, M, Marenzana, M, De Ruvo, L., Basta, D., P. Delogu   +41 more
core   +1 more source

Delayed X-Ray Brightening Accompanied by Variable Ionized Absorption Following a Tidal Disruption Event

The Astrophysical Journal
Supermassive black holes can experience super-Eddington peak mass fallback rates following the tidal disruption of a star. The theoretical expectation is that part of the infalling material is expelled by means of an accretion disk wind, whose ...
T. Wevers, M. Guolo, D. R. Pasham, E. R. Coughlin, F. Tombesi, Y. Yao, S. Gezari   +6 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

The effect of proton damage on the X-ray spectral response of MOS CCDs for the swift X-ray telescope [PDF]

, 2002
The effect of non-ionising energy loss(NIEL) of protons in charge-coupled devices is to displace silicon atoms and any dopant materials present from their lattice positions to form lattice defects which in turn can trap electrons [1].
Abbey, AF, Ambrosi, RM, R.M Ambrosi, Wells, A, Smith, D, A.A Wells, A.D.T Short, A.F Abbey, D.R Smith, Short, A   +9 more
core   +1 more source