Results 81 to 90 of about 975,965 (363)

KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells

open access: yesMolecular Oncology, EarlyView.
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock   +10 more
wiley   +1 more source

Solar X-ray spectrum reproduced in vacuum [PDF]

open access: yes, 1967
Desired low energy X rays are produced by modifying commercial ion tubes and combining them with standard power supplies and control circuitry.
Erdman, C. A., Kirchner, L. P.
core   +1 more source

The rate of X-ray-induced DNA double-strand break repair in the embryonic mouse brain is unaff ected by exposure to 50 Hz magnetic fi elds [PDF]

open access: yes, 2015
Following in utero exposure to low dose radiation (10 – 200 mGy), we recently observed a linear induction of DNA double-strand breaks (DSB) and activation of apoptosis in the embryonic neuronal stem/progenitor cell compartment.
Ahlbom IC   +30 more
core   +2 more sources

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

Portable X-rays–A new era?

open access: yesIPEM-Translation, 2022
This paper reports learning points from a small pilot study using a portable diagnostic X-ray set to radiograph patients in novel settings such as the patient home or care home.
Deborah Henderson   +3 more
doaj  

Dramatic increase in oxidative stress in carbon-irradiated normal human skin fibroblasts. [PDF]

open access: yesPLoS ONE, 2013
Skin complications were recently reported after carbon-ion (C-ion) radiation therapy. Oxidative stress is considered an important pathway in the appearance of late skin reactions.
Carine Laurent   +5 more
doaj   +1 more source

BAX: A dedicated X-Rays galaxy clusters Database [PDF]

open access: yes, 2003
We present BAX, Base de Donn\'ees amas de galaxies X (http://webast.ast.obs-mip.fr/bax), a project aiming at building a comprehensive database dedicated to X-rays clusters of galaxies allowing detailed information retrieval. BAX provides the user with {\it basic data} published in the literature on X-rays clusters of galaxies as well as with ...
arxiv   +1 more source

Compact Spectral Characterization of 5-500 MeV X-rays from the Texas Petawatt Laser-Driven Plasma Accelerator [PDF]

open access: yesarXiv, 2021
We reconstruct spectra of secondary x-rays generated from a 500 MeV - 2 GeV laser plasma electron accelerator. A compact (7.5 $\times$ 7.5 $\times$ 15 cm), modular x-ray calorimeter made of alternating layers of absorbing materials and imaging plates records the single-shot x-ray depth-energy distribution.
arxiv  

X-ray Polarimetry of X-ray Pulsars

open access: yesGalaxies
Radiation from X-ray pulsars (XRPs) was expected to be strongly linearly polarized owing to a large difference in their ordinary and extraordinary mode opacities. The launch of IXPE allowed us to check this prediction. IXPE observed a dozen X-ray pulsars, discovering pulse-phase dependent variation of the polarization degree (PD) and polarization angle
Juri Poutanen   +2 more
openaire   +3 more sources

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

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