Results 61 to 70 of about 5,944,987 (300)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Current evidence for spinal X-ray use in the chiropractic profession: a narrative review

Chiropractic & Manual Therapies, 2018
The use of routine spinal X-rays within chiropractic has a contentious history. Elements of the profession advocate for the need for routine spinal X-rays to improve patient management, whereas other chiropractors advocate using spinal X-rays only when ...
Hazel J Jenkins, Aron S Downie, Craig S Moore, Simon D French   +3 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

X-RAY MONITORING OF ULTRALUMINOUS X-RAY SOURCES [PDF]

The Astrophysical Journal, 2009
X-ray monitoring observations were performed with the Swift observatory of the ultraluminous X-ray sources Holmberg IX X-1, NGC 5408 X-1, and NGC 4395 X-2 and also of the nuclear X-ray source in NGC 4395. Holmberg IX X-1 remains in the hard X-ray spectral state as its flux varies by a factor of 7 up to an (isotropic) luminosity of 2.8E40 erg/s.
Kaaret, Philip, Feng, Hua
openaire   +2 more sources

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

The SRG/eROSITA diffuse soft X-ray background

Astronomy & Astrophysics
Context. The eROSITA bubbles (eRObub) were discovered in 2020 in the first SRG/eROSITA All-Sky Survey. They are some of the most extended structures in the X-ray sky.
Yeung Michael C. H., Mayer Martin G. F., Strong Andy, Freyberg Michael J., Ponti Gabriele, Dennerl Konrad, Mao Junjie, Sasaki Manami, Zheng Xueying, Sanders Jeremy S., Zhang Yi, Liu Jiejia, Gu Liyi, Becker Werner, Haberl Frank, Liu Teng, Merloni Andrea, Predehl Peter   +17 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

THE HARD X-RAY PERSPECTIVE ON THE SOFT X-RAY EXCESS [PDF]

The Astrophysical Journal, 2014
The X-ray spectra of many active galactic nuclei (AGN) exhibit a `soft excess' below 1keV, whose physical origin remains unclear. Diverse models have been suggested to account for it, including ionised reflection of X-rays from the inner part of the accretion disc, ionised winds/absorbers, and Comptonisation.
Vasudevan, Ranjan V., Mushotzky, Richard F., Reynolds, Christopher S., Fabian, Andrew C., Lohfink, Anne M., Zoghbi, Abderahmen, Gallo, Luigi C., Walton, Dominic   +7 more
openaire   +3 more sources