Results 151 to 160 of about 300,913 (307)
Oxidative stress is considered a central pathophysiological event in cardiovascular disease, including hypertension. Early age reduction in renal mass is associated with hypertension and oxidative stress in later life, which is aggravated by increased ...
Maria Peleli+6 more
doaj +1 more source
Mitochondrial oxidative stress, calcium and dynamics in cardiac ischaemia‐reperfusion injury
Abstract figure legend Heart attack causes ischaemia–reperfusion injury in cardiomyocytes. Mitochondria generate reactive oxygen species (ROS), leading to oxidative stress. High levels of mitochondrial calcium (Ca2+) activate the mitochondrial permeability transition pore (mPTP), and excess ROS levels can lower the Ca2+ required to activate the mPTP ...
Emily Rozich+5 more
wiley +1 more source
Isolation and Characterization of Xanthine Oxidase from Goats Milk
Xanthine oxidase (XO) plays a role in the formation of uric acid and can be obtained from various sources, including goat's milk. This study aims to provide xanthine oxidase enzymes with known purity, characteristics (pH, temperature, and molecular ...
Maretha Nur Rohma, Nuniek Herdyastuti
doaj +1 more source
ABSTRACT Introduction Discogenic low back pain can be severely disabling, clinically challenging to diagnose, and expensive to treat. Disc degeneration is characterized by disc dehydration, which diminishes the ability of the disc to distribute pressure, making it more susceptible to damage, and leading to annular tears, fissures, and a higher ...
Wouter K. M. van Os+6 more
wiley +1 more source
Rosa roxburghii fermented juice can improve dyslipidaemia by modulating gut microbiota disorders. Rosa roxburghii fermented juice may regulate lipid deposition by increasing metabolites such as choline, L‐Tyrosine, and L‐Phenylalanine in the liver to improve liver metabolic profile.
Duo Meng+9 more
wiley +1 more source
Peptides offer a promising analogue to synthetic drugs in treating hyperuricemia. This article introduces reliable amino acid patterns that cause the inhibitory xanthine oxidase (CSR) activity of peptides.
Anastasia V. Smirnova+1 more
doaj +1 more source
Effect of ELF e.m. fields on metalloprotein redox-active sites
The peculiarity of the distribution and geometry of metallic ions in enzymes pushed us to set the hypothesis that metallic ions in active-site act like tiny antennas able to pick up very feeble e.m. signals.
Badon, T.+6 more
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Torreya grandis seed polyphenols (TGSP), primarily containing gallic acid and epicatechin, exhibit selective free radical scavenging activity. TGSP pretreatment effectively inhibits LPS‐induced inflammatory responses by reducing TNF‐α, NO, and IL‐6 production. TGSP also alleviates H2O2‐induced oxidative stress by enhancing antioxidant enzyme activities
Ran Liu+7 more
wiley +1 more source
XANTHINE OXIDASE ACTIVITY IN REGENERATING LIVER [PDF]
Muriel Feigelson+2 more
openalex +1 more source
Phenolic Compounds in Exercise Physiology: Dual Role in Oxidative Stress and Recovery Adaptation
Exercise increases mitochondrial activity and reactive oxygen species (ROS) production, which can lead to oxidative stress. However, phenolic compounds act as potent antioxidants, counteracting ROS and thereby mitigating oxidative stress. This graphical abstract illustrates the dual role of exercise and dietary antioxidants in the regulation of redox ...
Kübra Özdemir, Yeliz Demir
wiley +1 more source