Results 151 to 160 of about 300,913 (307)

Renal denervation attenuates hypertension and renal dysfunction in a model of cardiovascular and renal disease, which is associated with reduced NADPH and xanthine oxidase activity

open access: yesRedox Biology, 2017
Oxidative stress is considered a central pathophysiological event in cardiovascular disease, including hypertension. Early age reduction in renal mass is associated with hypertension and oxidative stress in later life, which is aggravated by increased ...
Maria Peleli   +6 more
doaj   +1 more source

Mitochondrial oxidative stress, calcium and dynamics in cardiac ischaemia‐reperfusion injury

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Heart attack causes ischaemia–reperfusion injury in cardiomyocytes. Mitochondria generate reactive oxygen species (ROS), leading to oxidative stress. High levels of mitochondrial calcium (Ca2+) activate the mitochondrial permeability transition pore (mPTP), and excess ROS levels can lower the Ca2+ required to activate the mPTP ...
Emily Rozich   +5 more
wiley   +1 more source

Isolation and Characterization of Xanthine Oxidase from Goats Milk

open access: yesJurnal Pijar MIPA (Pengkajian Ilmu dan Pengajaran Matematika dan Ilmu Pengetahuan Alam)
Xanthine oxidase (XO) plays a role in the formation of uric acid and can be obtained from various sources, including goat's milk. This study aims to provide xanthine oxidase enzymes with known purity, characteristics (pH, temperature, and molecular ...
Maretha Nur Rohma, Nuniek Herdyastuti
doaj   +1 more source

14. Discogenic Low Back Pain

open access: yesPain Practice, Volume 25, Issue 7, September 2025.
ABSTRACT Introduction Discogenic low back pain can be severely disabling, clinically challenging to diagnose, and expensive to treat. Disc degeneration is characterized by disc dehydration, which diminishes the ability of the disc to distribute pressure, making it more susceptible to damage, and leading to annular tears, fissures, and a higher ...
Wouter K. M. van Os   +6 more
wiley   +1 more source

Exploring the Prevention of Lipid Deposition Caused by High‐Fat Diet and Its Mechanism of Action of Rosa roxburghii Fermented Juice Based on Liver Metabolomics and Gut Microbiota

open access: yesFood Science &Nutrition, Volume 13, Issue 8, August 2025.
Rosa roxburghii fermented juice can improve dyslipidaemia by modulating gut microbiota disorders. Rosa roxburghii fermented juice may regulate lipid deposition by increasing metabolites such as choline, L‐Tyrosine, and L‐Phenylalanine in the liver to improve liver metabolic profile.
Duo Meng   +9 more
wiley   +1 more source

Amino Acid Patterns that Determine Antihyperuricemic Activity of Peptides: Identification and Predictive Analysis

open access: yesТехника и технология пищевых производств
Peptides offer a promising analogue to synthetic drugs in treating hyperuricemia. This article introduces reliable amino acid patterns that cause the inhibitory xanthine oxidase (CSR) activity of peptides.
Anastasia V. Smirnova   +1 more
doaj   +1 more source

Effect of ELF e.m. fields on metalloprotein redox-active sites

open access: yes, 2007
The peculiarity of the distribution and geometry of metallic ions in enzymes pushed us to set the hypothesis that metallic ions in active-site act like tiny antennas able to pick up very feeble e.m. signals.
Badon, T.   +6 more
core  

Torreya grandis Seed Polyphenols Protect RAW264.7 Macrophages by Inhibiting Oxidative Stress and Inflammation

open access: yesFood Science &Nutrition, Volume 13, Issue 8, August 2025.
Torreya grandis seed polyphenols (TGSP), primarily containing gallic acid and epicatechin, exhibit selective free radical scavenging activity. TGSP pretreatment effectively inhibits LPS‐induced inflammatory responses by reducing TNF‐α, NO, and IL‐6 production. TGSP also alleviates H2O2‐induced oxidative stress by enhancing antioxidant enzyme activities
Ran Liu   +7 more
wiley   +1 more source

XANTHINE OXIDASE ACTIVITY IN REGENERATING LIVER [PDF]

open access: bronze, 1957
Muriel Feigelson   +2 more
openalex   +1 more source

Phenolic Compounds in Exercise Physiology: Dual Role in Oxidative Stress and Recovery Adaptation

open access: yesFood Science &Nutrition, Volume 13, Issue 8, August 2025.
Exercise increases mitochondrial activity and reactive oxygen species (ROS) production, which can lead to oxidative stress. However, phenolic compounds act as potent antioxidants, counteracting ROS and thereby mitigating oxidative stress. This graphical abstract illustrates the dual role of exercise and dietary antioxidants in the regulation of redox ...
Kübra Özdemir, Yeliz Demir
wiley   +1 more source

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