Results 151 to 160 of about 299,059 (319)

Exploring Antioxidant Synergism Mechanism of 3D Printing Based Shanyao–Fuling–Yiyiren Decoction via Fuzzy Mathematical Method, Network Pharmacology, and In Vitro Experimental Validation

open access: yesFood Science &Nutrition, Volume 13, Issue 6, June 2025.
SFY‐based polyherbal formulation was selected based on fuzzy mathematical model. The best combinations with synergistic effect were optimized and identified by central composite circumscribed design. Network pharmacology and molecular docking‐based approach revealed that the potential mechanisms of decoction against oxidant damage via multicomponent ...
Haoran Fan   +10 more
wiley   +1 more source

Sex‐specific associations of Roseburia with uric acid metabolism and hyperuricemia risk in females

open access: yesiMetaOmics, Volume 2, Issue 2, June 2025.
Researchers recruited 623 participants, including 270 females, and used 16S rDNA sequencing to investigate gender differences in hyperuricemia. In healthy females, Roseburia was enriched, positively correlating with estrogen and negatively with uric acid, suggesting it is a potential biomarker affecting uric acid levels in females.
Zhihan Yang   +8 more
wiley   +1 more source

Evaluating the Potential Adverse Effects of Favipiravir on Biochemical, Histopathological, and Spermatological Parameters in Male Rats' Testicular Tissue

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 39, Issue 6, June 2025.
ABSTRACT Favipiravir is a selective RNA polymerase inhibitor and a broad‐spectrum antiviral drug. Favipiravir reduces cell proliferation by inhibiting RNA transcription, particularly in rapidly proliferating cells such as spermatogonia. The aim of this study was to investigate the effects and mechanism of action of favipiravir (T‐705) on sperm quality ...
Ali Doğan Ömür   +6 more
wiley   +1 more source

Ferulic acid: extraction, estimation, bioactivity and applications for human health and food

open access: yesJournal of the Science of Food and Agriculture, Volume 105, Issue 8, Page 4168-4177, June 2025.
Abstract Ferulic acid ((E)‐3‐(4‐hydroxy‐3‐methoxy‐phenyl) prop‐2‐enoic acid) is a derivative of caffeic acid found in most plants. This abundant phenolic compound exhibits significant antioxidant capacity and a broad spectrum of therapeutic effects, including anti‐inflammatory, antimicrobial, anticancer, antidiabetic, cardiovascular and neuroprotective
Mukul Kumar   +13 more
wiley   +1 more source

Fructose‐Induced Impairment of Liver and Skeletal Muscle Metabolism Is Prevented by Administration of Shouchella clausii Spores by Preserving Mitochondrial Function and Insulin Sensitivity

open access: yesMolecular Nutrition &Food Research, Volume 69, Issue 11, June 2025.
S. clausii SF174 spores were effective in preventing the onset of low‐grade inflammation and insulin resistance induced by fructose‐rich diet in young rats, preserving the mitochondria from changes in the respiratory capacity in both liver and skeletal muscle, maintaining unaltered the oxidative balance, thus counteracting the deleterious effects of ...
Angela Di Porzio   +7 more
wiley   +1 more source

Xanthine oxidase inhibitors treatment or discontinuation effects on mortality: evidence of xanthine oxidase inhibitors withdrawal syndrome. [PDF]

open access: yesFront Pharmacol, 2023
Kuwabara M   +7 more
europepmc   +1 more source

Oxidative Stress in Antigen Processing and Presentation

open access: yesMedComm – Oncology, Volume 4, Issue 2, June 2025.
Reactive oxygen species (ROS) play a crucial role in antigen processing and presentation, essential for linking innate and adaptive immunity. While balanced ROS levels promote immune function, excess ROS can disrupt antigen recognition, resulting in immune dysfunction.
Qinxia Chang   +9 more
wiley   +1 more source

Sulfite: Cytochrome \u3cem\u3ec\u3c/em\u3e Oxidoreductase from \u3cem\u3eThiobacillus novellus\u3c/em\u3e [PDF]

open access: yes, 2000
Direct oxidation of sulfite to sulfate occurs in various photo- and chemotrophic sulfur oxidizing microorganisms as the final step in the oxidation of reduced sulfur compounds and is catalyzed by sulfite:cytochrome c oxidoreductase (EC1.8.2.1).
Bennett, Brian   +6 more
core   +1 more source

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