Maternal Electronic Cigarette Inhalation Exposure During Gestation: Impacts on Prolactin and Xanthine Oxidase. [PDF]
Griffith JA +9 more
europepmc +1 more source
Harnessing Trace Elements: Novel Radiosensitization Strategies for Enhanced Cancer Radiotherapy
ABSTRACT Radiotherapy (RT) is one of the core methods of comprehensive cancer treatment. Globally, more than 40% of cancer patients rely on radiotherapy to achieve tumor control, cure or palliative relief. However, radiation resistance, immunosuppression and normal tissue injury limit its clinical application.
Yuhuan Zhang +6 more
wiley +1 more source
<i>Lachnoclostridium</i>-mediated fermentation of <i>Konjac glucomannan</i>: short chain fatty acids production and inhibitory xanthine oxidase activity. [PDF]
Deng J +13 more
europepmc +1 more source
ABSTRACT The poor soft tissue integration around titanium implants creates a microgap that serves as a pathway for pathogen invasion, resulting in infection, inflammation, and the progression of peri‐implantitis. As the implant’s transmucosal component, the abutment determines the degree of peri‐implant soft tissue attachment.
Xuan Li +7 more
wiley +1 more source
Inhibitory Effect of Whey Protein-Derived Peptide Leu-Asp-Gln-Trp on Xanthine Oxidase. [PDF]
Toda K +5 more
europepmc +1 more source
Benzofuran‐Based Uricosuric Agents: History, Roles, and Challenges
Benzofuran‐based uricosuric agents represent a privileged medicinal chemistry scaffold for gout therapy. Structural optimization of benzbromarone‐related derivatives has improved hURAT1 inhibitory potency, metabolic stability, and urate‐lowering efficacy, while reducing hepatotoxic liability.
Raed M. Al‐Zoubi +7 more
wiley +1 more source
The symbiotic interaction between Demodex folliculorum and Corynebacterium kroppenstedtii subsp. demodicis. Created by the author based on genomic and functional analyses presented in this work. The tripartite interaction between the human host, the mite Demodex folliculorum, and its endosymbiont Corynebacterium kroppenstedtii subsp. demodicis.
T. Steegmüller +6 more
wiley +1 more source
Effects of barley green on uric acid, inflammatory factors, xanthine oxidase activity and body composition of patients with hyperuricemia: a randomized controlled trial. [PDF]
Cui M +5 more
europepmc +1 more source
Repurposing Purine Analog Antivirals to Modulate Serum Uric Acid: Evidence From Real‐World Data
ABSTRACT Xanthine oxidase (XO) inhibitors remain the standard pharmacologic therapy for hyperuricemia. However, additional enzymatic components of the purine degradation pathway may contribute to uric acid synthesis. Guanine deaminase (GD) catalyzes the conversion of guanine to xanthine, providing substrate for downstream oxidation by XO.
Joseph Magagnoli +5 more
wiley +1 more source

