Results 151 to 160 of about 37,916 (254)

Advances in Xanthine Oxidase Inhibition: A Review of Potential Bioactive Synthetic Compounds. [PDF]

Arch Pharm (Weinheim)
Antoniolli G, de Moraes GR, da Costa RPN, de Campos GAR, Coelho F.   +4 more
europepmc   +1 more source

The xanthine oxidase-aldehyde system [PDF]

Biochemical Journal, 1938
openaire   +2 more sources

Therapeutic Effect of Zingerone on Reproductive Damage in Diabetic Male Rats: Potential Role of Sirt1/Nrf2/HO‐1 and Bax/Bcl‐2 Signaling Pathways

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 6, June 2026.
Diabetes mellitus causes significant damage to the male reproductive system. Sirt1/Nrf2/HO‐1 signaling pathway acts as a line of defense against ROS in reproductive organs. In STZ‐induced diabetic rats, the proapoptotic Bax protein expression was found to be elevated, whereas the antiapoptotic Bcl‐2 protein expression was reduced.
Edanur Güler Ekmen, Mehmet Çay, İbrahim Halil Güngör, Ali Osman Çeribaşı   +3 more
wiley   +1 more source

Guideline adherence of xanthine oxidase inhibitor utilization to treat gout in primary care. [PDF]

J Manag Care Spec Pharm
Claus LW, Auten ME, Saseen JJ, Billups SJ.   +3 more
europepmc   +1 more source

Tocilizumab and Dexamethasone Reduce TNF‐α and IL‐33 and Oxidative Stress in Kidney Tissue in Oleic Acid‐Induced ARDS Model

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 6, June 2026.
Oleic acid causes ARDS‐associated AKI. Tocilizumab and dexamethasone reduces ARDS‐induced kidney injury. The width of the filtration slits increases in kidney injury. Tocilizumab and dexamethasone suppress TNF‐a and IL‐33. ABSTRACT The most common extrapulmonary organ injury in cases of acute respiratory distress syndrome (ARDS) is acute kidney injury (
Huseyin Serkan Erol, Beste Demirci, Mohammad Alhilal, Funda Terzi, Nazli Kelercioglu   +4 more
wiley   +1 more source

Gnetumgams A and B: two new 2-phenylbenzofuran derivatives from the lianas of <i>Gnetum montanum</i> with xanthine oxidase inhibitory activity. [PDF]

RSC Adv
Van Do TN, Nguyen MH, Nguyen HX, Nguyen NT, Thi Nguyen MT.   +4 more
europepmc   +1 more source

Acetate‐Linked Energy Metabolism as a Determinant of Early Haemophilus influenzae Infection Fitness

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
The Pta–AckA pathway is critical for Haemophilus influenzae energy generation, metabolic homeostasis, stress resistance, and intracellular colonization, highlighting its potential as a target for management of H. influenzae infections.
Marufa Nasreen, Jennifer Hosmer, Saurab Kishore Munshi, Riya Joshi, Ayaho Yamamoto, Horst J. Schirra, Peter Sly, Alastair G. McEwan, Ulrike Kappler   +8 more
wiley   +1 more source

Identification of deferasirox as a human xanthine oxidase inhibitor. [PDF]

Life Med
Qi Y, He X, Wu X, Zhou T, Liang N, Jiao J, Chen Y, Yuan Y, Zhang Y, Wang Y, Liu Y, Ding Q.   +11 more
europepmc   +1 more source

The Role of Neutrophils and NETosis in Diseases: The Implications for Therapy

MedComm, Volume 7, Issue 6, June 2026.
Neutrophils secrete cytokines, express specific surface proteins, increase or decrease in cell count, and their ratio to lymphocyte count can be used as biomarkers to characterize collective status and disease progression. Neutrophils can monitor and track the body's health status, “Wei Bing” status, disease status, and different times of disease ...
Zhen Ma, Qing Wang, Yusheng Zhang, Yang Li, Hongwei Wu, Hongjun Yang, Xianyu Li   +6 more
wiley   +1 more source

Hyperuricemia in ob/ob mice relates to hepatocellular pyruvate metabolism/ xanthine oxidase axis. [PDF]

PLoS One
Zhang S, Hu S, Tan H, Jia E.
europepmc   +1 more source