Results 161 to 170 of about 79,386 (326)

Chemoprevention of Azoxymethane‐induced Rat Colon Carcinogenesis by a Xanthine Oxidase Inhibitor, 1′‐Acetoxychavicol Acetate [PDF]

open access: hybrid, 1997
Takuji Tanaka   +10 more
openalex   +1 more source

Genetic Determinants of Hematopoietic Toxicity Risk in Thai Pediatric Patients Undergoing 6‐Mercaptopurine Treatment

open access: yesClinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT The nucleoside diphosphate‐linked moiety X‐type motif 15 (NUDT15) has been identified as a key genetic determinant of 6‐mercaptopurine (6‐MP)‐induced hematopoietic toxicity in populations with a high frequency of NUDT15 variants but a low frequency of thiopurine S‐methyltransferase (TPMT) variants.
Kanyarat Khaeso   +8 more
wiley   +1 more source

Different roles of xanthine oxidase and leukocyte on acute and chronic gastric legions induced by ischemia-reperfusion in rats

open access: diamond, 1997
Kouichirou Wada   +5 more
openalex   +1 more source

Biocatalytic Construction of a Chemical Exchange Saturation Transfer Magnetic Resonance Imaging Nucleoside Probe: Synthesis and Evaluation of 5‐Methyl‐5,6‐Dihydrothymidine

open access: yesAdvanced Synthesis &Catalysis, Volume 368, Issue 1, January 2026.
Al‐Hilfi et al. present a biocatalytic strategy for synthesizing 5‐methyl‐5,6‐dihydrothymidine (5‐MDHT), a sensitive MRI contrast agent. The study demonstrates that recombinant enzyme catalysis offers an efficient, sustainable, and eco‐friendly alternative to traditional chemical synthesis for producing clinically relevant imaging probes.
Aimen Al‐Hilfi   +8 more
wiley   +1 more source

Xanthine Oxidase

open access: yesJournal of Biological Chemistry, 1964
Lorance Greenlee, Philip Handler
openaire   +1 more source

Constructing Dual‐Atomic Fe─Fe Sites Nanozyme for Targeted Osteoarthritis Therapy through Mitigating Oxidative Stress and Cartilage Degeneration

open access: yesAdvanced Science, Volume 13, Issue 1, 5 January 2026.
A novel bimetallic nanozyme (Fe2–NCs) with well‐defined Fe–Fe active sites is synthesized through a host–guest coordination strategy, which exhibits an exceptional therapeutic efficacy in osteoarthritis therapy. Experimental and theoretical analyses uncover the intrinsic catalytic mechanism at the atomic level, offering fundamental insights and design ...
Ting Ying   +6 more
wiley   +1 more source

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