Results 161 to 170 of about 299,059 (319)

Lower time‐averaged serum uric acid was associated with increased mortality in peritoneal dialysis patients

Therapeutic Apheresis and Dialysis, Volume 29, Issue 3, Page 479-490, June 2025.
Abstract Background The relationship between time‐averaged serum uric acid (TA‐SUA) levels and prognosis in peritoneal dialysis (PD) patients are rarely discussed. Methods This was a retrospective cohort study. PD patients recruited from January 1, 2011, to December 31, 2020, were included.
Lu Li, Hongxia Zhang, Botao Zhang, Fangyuan Yang, Mengting Wang, Wenlong Qiu, Lina Fu, Menghua Chen, Na Tian   +8 more
wiley   +1 more source

Mechanistic insights into the inhibition of quercetin on xanthine oxidase.

International Journal of Biological Macromolecules, 2018
Cen Zhang, Rui Wang, Guowen Zhang, D. Gong   +3 more
semanticscholar   +1 more source

PTPN2 and Leukopenia in Individuals With Normal TPMT and NUDT15 Metabolizer Status Taking Azathioprine

Clinical and Translational Science, Volume 18, Issue 6, June 2025.
ABSTRACT Leukopenia is a common dose‐dependent side effect of azathioprine, often leading to drug discontinuation. Variants in TPMT and NUDT15 are associated with azathioprine‐induced leukopenia but only explain 25% of cases. Thus, we aimed to identify novel genetic risk factors among TPMT and NUDT15 normal metabolizers through a genome‐wide ...
Laura L. Daniel, Puran Nepal, Jacy Zanussi, Alyson L. Dickson, Peter Straub, Tyne W. Miller‐Fleming, Wei‐Qi Wei, Adriana M. Hung, Nancy J. Cox, Vivian K. Kawai, Jonathan D. Mosley, Charles Michael Stein, QiPing Feng, Ge Liu, Ran Tao, Cecilia P. Chung   +15 more
wiley   +1 more source

Xanthine Oxidase

, 1958
Irwin Fridovich, Philip Handler
openalex   +1 more source

Hormones and liver cytoplasm. 2. Adenosine triphosphatase, glucose 6-phosphatase and xanthine oxidase as affected by hypophysectomy, growth-hormone treatment and adrenalectomy [PDF]

, 1956
E. Emmet Reid, M. A. O'Neal, Isaac Lewin
openalex   +1 more source

The impact of xanthine oxidase (XO) on hemolytic diseases

Redox Biology, 2018
Heidi M. Schmidt, E. Kelley, A. Straub
semanticscholar   +1 more source

Impact of Renal Impairment on the Pharmacodynamic and Pharmacokinetic Profiles of Epaminurad, a Novel Uric Acid Transporter 1 Inhibitor

Clinical and Translational Science, Volume 18, Issue 6, June 2025.
ABSTRACT Epaminurad, a novel uricosuric agent, exhibits potent inhibitory activity against the human uric acid transporter. This study aimed to investigate the effects of renal function and food intake on the pharmacokinetic, pharmacodynamic, and safety characteristics of 9 mg epaminurad. This study was designed as a phase 1, partially randomized, open‐
Seo Yeong Park, Jun Gi Hwang, Sung Kweon Cho, Min Kyu Park   +3 more
wiley   +1 more source

Studies on Xanthine Oxidase [PDF]

, 1926
Keizo Kodama
openalex   +1 more source

Biomarkers in heart failure: Traditional and emerging indicators for prognosis

ESC Heart Failure, Volume 12, Issue 3, Page 1535-1538, June 2025.
Arnold Péter Ráduly, László Nagy, Beáta Bódi, Zoltán Papp, Attila Borbély   +4 more
wiley   +1 more source

Dual ETA‐ETB receptor antagonism improves metabolic syndrome‐induced heart failure with preserved ejection fraction

Fundamental &Clinical Pharmacology, Volume 39, Issue 3, June 2025.
Abstract Background Metabolic syndrome (MetS) is a multifaceted disease associated with heart failure (HF), which affects the vascular system. The endothelin (ET) system is a key player in MetS and HF; therefore, targets for ET receptors are of therapeutic interest.
Francesca Lockwood, Marianne Lachaux, Najah Harouki, Matthieu Soulié, Lionel Nicol, Sylvanie Renet, Anaïs Dumesnil, Magali Vercauteren, Jeremy Bellien, Marc Iglarz, Vincent Richard, Paul Mulder   +11 more
wiley   +1 more source