Results 301 to 310 of about 44,980 (368)
Some of the next articles are maybe not open access.
Xanthines and Phosphodiesterase Inhibitors.
Handbook of Experimental Pharmacology, 2017Theophylline is an orally acting xanthine that has been used since 1937 for the treatment of respiratory diseases including asthma and chronic obstructive pulmonary disease (COPD). However, in most treatment guidelines, xanthines have now been consigned to third-line therapy because of their narrow therapeutic window and propensity for drug-drug ...
D. Spina, Clive P. Page
semanticscholar +3 more sources
Aromaticity of caffeine, xanthine and the dimethyl xanthines
Tetrahedron Letters, 2014Xanthine, caffeine and three isomeric dimethyl xanthines (theobromine, theophylline and paraxanthine) are often described as aromatic on various criteria. Here we complete the picture by assessing these molecules for aromaticity on the ring-current criterion.
Patrick W. Fowler, Christopher M. Gibson
openaire +2 more sources
Journal of Organic Chemistry, 2017
The xanthine scaffold is known to be the forefather of a class of biological active molecules. Xanthine is a planar framework in which an aryl substituent linked in the 1 or 3 position is driven out of the xanthine plane because of the steric hindrance ...
Michele Mancinelli +3 more
semanticscholar +1 more source
The xanthine scaffold is known to be the forefather of a class of biological active molecules. Xanthine is a planar framework in which an aryl substituent linked in the 1 or 3 position is driven out of the xanthine plane because of the steric hindrance ...
Michele Mancinelli +3 more
semanticscholar +1 more source
The reactions of chloroperoxidase in the presence of xanthine/xanthine oxidase
Biochemical and Biophysical Research Communications, 1989Spectral data are presented which indicate that chloroperoxidase is converted to compound II during the reaction with superoxide/hydrogen peroxide generated in the xanthine/xanthine oxidase system. Upon completion of compound II formation, compound II returns back to the native state of chloroperoxidase without formation of detectable intermediates. It
H. Brian Dunford +2 more
openaire +3 more sources
Palladium compounds of xanthine and xanthine derivatives
Inorganica Chimica Acta, 1983The biological importance of purine bases is well known. The interaction of metal ions with nucleic acids, nucleotides and nucleotides has been an active area of inorganic and structural chemistry during the last few years, and a number of recent reviews exist on the subject [1, 2].
E. Colacio +4 more
openaire +2 more sources
Analytical Chemistry, 2015
The natural xanthines caffeine, theobromine, and theophylline are of major commercial importance as flavor constituents in coffee, cocoa, tea, and a number of other beverages.
Didier Diomandé +10 more
semanticscholar +1 more source
The natural xanthines caffeine, theobromine, and theophylline are of major commercial importance as flavor constituents in coffee, cocoa, tea, and a number of other beverages.
Didier Diomandé +10 more
semanticscholar +1 more source
American Review of Respiratory Disease, 2015
The study was designed to obtain information on selected extrapulmonary effects of enprofylline, an adenosine-non-blocking alkylxanthine that is about 5 times more potent as a bronchodilator than the adenosine receptor antagonist theophylline. Effects of
N. Johannesson +3 more
semanticscholar +1 more source
The study was designed to obtain information on selected extrapulmonary effects of enprofylline, an adenosine-non-blocking alkylxanthine that is about 5 times more potent as a bronchodilator than the adenosine receptor antagonist theophylline. Effects of
N. Johannesson +3 more
semanticscholar +1 more source
The FEBS Journal, 2008
Reactive oxygen species are generated by various biological systems, including NADPH oxidases, xanthine oxidoreductase, and mitochondrial respiratory enzymes, and contribute to many physiological and pathological phenomena. Mammalian xanthine dehydrogenase (XDH) can be converted to xanthine oxidase (XO), which produces both superoxide anion and ...
Takeshi Nishino +4 more
openaire +3 more sources
Reactive oxygen species are generated by various biological systems, including NADPH oxidases, xanthine oxidoreductase, and mitochondrial respiratory enzymes, and contribute to many physiological and pathological phenomena. Mammalian xanthine dehydrogenase (XDH) can be converted to xanthine oxidase (XO), which produces both superoxide anion and ...
Takeshi Nishino +4 more
openaire +3 more sources