Results 61 to 70 of about 5,171 (202)
Saponin-based adjuvants induce cross-presentation in dendritic cells by intracellular lipid body formation [PDF]
Saponin-based adjuvants (SBAs) are being used in animal and human (cancer) vaccines, as they induce protective cellular immunity. Their adjuvant potency is a factor of inflammasome activation and enhanced antigen cross-presentation by dendritic cells ...
Adema, Gosse J. +10 more
core +2 more sources
Antiproliferative and apoptotic effects of xanthohumol in cholangiocarcinoma [PDF]
Cholangiocarcinoma remains the second most prevalent hepatic neoplasm in the United States with a 5-year survival rate of less than 10%. Currently, no systemic therapy has demonstrated efficacy. Therefore, an urgent need for the identification of molecularly targeted compound(s) remains.
Walden, Daniel +4 more
openaire +2 more sources
ABSTRACT Skeletal system diseases, encompassing chronic disorders of the skeletal system which commonly include osteoarthritis, rheumatoid arthritis, osteoporosis and osteosarcoma. Their incidence rates have been increasing in recent years, resulting in significant social and economic burdens.
Qian Yi +8 more
wiley +1 more source
Xanthohumol (XN), a prenylated chalcone from hops, has been reported to exhibit a variety of health-beneficial effects. However, poor bioavailability may limit its application in the prevention and therapy of diseases.
Abdo Mahli +7 more
doaj +1 more source
Protagonizando la generación de conocimiento a través de la integración de la investigación básica y clínica: Del quirófano al laboratorio [PDF]
Fac.
Fernández-Tresguerres Hernández, Jesús Ángel +7 more
core +1 more source
Mechanistic studies of anti-hyperpigmentary compounds: elucidating their inhibitory and regulatory actions. [PDF]
Searching for depigmenting agents from natural sources has become a new direction in the cosmetic industry as natural products are generally perceived as relatively safer.
Cheng, CH +3 more
core +2 more sources
BIOACTIVE SUBSTANCES FROM HOPS – XANTHOHUMOL
Xanthohumol (3’-[3,3–dimetyl allyl]-2’,4’,4-trihydroxy-6’-methoxychalcone) is the principal prenylated flavonoid of the female inflorescences of the hop plant (‘ Humulus lupulus L.), an ingredient of beer. Xanthohumol has been characterized a cancer chromoprotective agent in in vitro studies, while other prenylate compounds are potent phitoestrogen ...
Elena Mudura +3 more
openaire +1 more source
Significance Statement This study of three glandular trichome‐producing species (cannabis, hop and tomato) defines tissue‐specific transcriptomic atlases for five organs (trichome, flower, leaf, stem and root), providing co‐expression and gene regulatory networks and identifying candidate regulators of specialised metabolism in trichomes of each ...
Muluneh Tamiru‐Oli +10 more
wiley +1 more source
Xanthohumol (XN), a natural prenylated flavonoid extracted and isolated from the hop plant (Humulus lupulus), possesses diverse pharmacological activities.
Xiaoqing Yuan +6 more
doaj +1 more source
Detecting beer intake by unique metabolite patterns [PDF]
Evaluation of the health related effects of beer intake is hampered by the lack of accurate tools for assessing intakes (biomarkers). Therefore, we identified plasma and urine metabolites associated with recent beer intake by untargeted metabolomics and ...
Bech, Lene +5 more
core +2 more sources

