Results 61 to 70 of about 5,171 (202)

Saponin-based adjuvants induce cross-presentation in dendritic cells by intracellular lipid body formation [PDF]

open access: yes, 2016
Saponin-based adjuvants (SBAs) are being used in animal and human (cancer) vaccines, as they induce protective cellular immunity. Their adjuvant potency is a factor of inflammasome activation and enhanced antigen cross-presentation by dendritic cells ...
Adema, Gosse J.   +10 more
core   +2 more sources

Antiproliferative and apoptotic effects of xanthohumol in cholangiocarcinoma [PDF]

open access: yesOncotarget, 2017
Cholangiocarcinoma remains the second most prevalent hepatic neoplasm in the United States with a 5-year survival rate of less than 10%. Currently, no systemic therapy has demonstrated efficacy. Therefore, an urgent need for the identification of molecularly targeted compound(s) remains.
Walden, Daniel   +4 more
openaire   +2 more sources

Targeting Ferroptosis With Natural Products for the Treatment of Skeletal System Disease: An Updated Review

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 7, April 2026.
ABSTRACT Skeletal system diseases, encompassing chronic disorders of the skeletal system which commonly include osteoarthritis, rheumatoid arthritis, osteoporosis and osteosarcoma. Their incidence rates have been increasing in recent years, resulting in significant social and economic burdens.
Qian Yi   +8 more
wiley   +1 more source

Therapeutic Application of Micellar Solubilized Xanthohumol in a Western-Type Diet-Induced Mouse Model of Obesity, Diabetes and Non-Alcoholic Fatty Liver Disease

open access: yesCells, 2019
Xanthohumol (XN), a prenylated chalcone from hops, has been reported to exhibit a variety of health-beneficial effects. However, poor bioavailability may limit its application in the prevention and therapy of diseases.
Abdo Mahli   +7 more
doaj   +1 more source

Protagonizando la generación de conocimiento a través de la integración de la investigación básica y clínica: Del quirófano al laboratorio [PDF]

open access: yes, 2017
Fac.
Fernández-Tresguerres Hernández, Jesús Ángel   +7 more
core   +1 more source

Mechanistic studies of anti-hyperpigmentary compounds: elucidating their inhibitory and regulatory actions. [PDF]

open access: yes, 2014
Searching for depigmenting agents from natural sources has become a new direction in the cosmetic industry as natural products are generally perceived as relatively safer.
Cheng, CH   +3 more
core   +2 more sources

BIOACTIVE SUBSTANCES FROM HOPS – XANTHOHUMOL

open access: yesHop and Medicinal Plants, 2008
Xanthohumol (3’-[3,3–dimetyl allyl]-2’,4’,4-trihydroxy-6’-methoxychalcone) is the principal prenylated flavonoid of the female inflorescences of the hop plant (‘ Humulus lupulus L.), an ingredient of beer. Xanthohumol has been characterized a cancer chromoprotective agent in in vitro studies, while other prenylate compounds are potent phitoestrogen ...
Elena Mudura   +3 more
openaire   +1 more source

Insights into glandular trichome biology from analysis of organ‐specific gene expression programmes in cannabis, hop and tomato

open access: yesThe Plant Journal, Volume 125, Issue 6, March 2026.
Significance Statement This study of three glandular trichome‐producing species (cannabis, hop and tomato) defines tissue‐specific transcriptomic atlases for five organs (trichome, flower, leaf, stem and root), providing co‐expression and gene regulatory networks and identifying candidate regulators of specialised metabolism in trichomes of each ...
Muluneh Tamiru‐Oli   +10 more
wiley   +1 more source

Stepwise Targeted Matching Strategy for Comprehensive Profiling of Xanthohumol Metabolites In Vivo and In Vitro Using UHPLC-Q-Exactive Orbitrap Mass Spectrometer

open access: yesMolecules, 2023
Xanthohumol (XN), a natural prenylated flavonoid extracted and isolated from the hop plant (Humulus lupulus), possesses diverse pharmacological activities.
Xiaoqing Yuan   +6 more
doaj   +1 more source

Detecting beer intake by unique metabolite patterns [PDF]

open access: yes, 2016
Evaluation of the health related effects of beer intake is hampered by the lack of accurate tools for assessing intakes (biomarkers). Therefore, we identified plasma and urine metabolites associated with recent beer intake by untargeted metabolomics and ...
Bech, Lene   +5 more
core   +2 more sources

Home - About - Disclaimer - Privacy