Results 241 to 250 of about 85,730 (276)
Some of the next articles are maybe not open access.
Selective epitaxy of GaAs, AlxGa1−xAs, and InxGa1−xAs
Journal of Crystal Growth, 1991Abstract Many device structures benefit from the ability to selectively deposit epitaxial materials. Through the use of a masking material, such as Si3N4 or SiO2, on the substrate surface, patterns generated through standard lithographic procedures can be used to define regions for selective deposition. Highly selective growth can be achieved through
T.F. Kuech +8 more
openaire +1 more source
The FASEB Journal, 1995
Cellular inflammatory responses and early mechanisms of vascular injury are invariably associated with activation of blood coagulation and deposition of insoluble fibrin. This process occurs on vascular cell surfaces through the ability of the coagulation protease factor Xa to generate thrombin.
openaire +2 more sources
Cellular inflammatory responses and early mechanisms of vascular injury are invariably associated with activation of blood coagulation and deposition of insoluble fibrin. This process occurs on vascular cell surfaces through the ability of the coagulation protease factor Xa to generate thrombin.
openaire +2 more sources
1992
The assembly and function of the prothrombinase complex on the bovine and human platelet membrane is mediated through binding interactions in which factor Va bound to the platelet surface forms at least part of the "receptor" for factor Xa in a 1:1 stoichiometric complex. A model depicting these binding interactions is shown in Fig. 12.
P B, Tracy, M E, Nesheim, K G, Mann
openaire +2 more sources
The assembly and function of the prothrombinase complex on the bovine and human platelet membrane is mediated through binding interactions in which factor Va bound to the platelet surface forms at least part of the "receptor" for factor Xa in a 1:1 stoichiometric complex. A model depicting these binding interactions is shown in Fig. 12.
P B, Tracy, M E, Nesheim, K G, Mann
openaire +2 more sources
2023
This chapter describes factor Xa as a key enzyme involved in thrombosis and clot formation. It considers factor Xa inhibitors as potential anticoagulants for the treatment of deep-vein thrombosis and pulmonary embolism. It also highlights the first factor Xa inhibitors to reach the market and covers the design process that led to the discovery of ...
openaire +1 more source
This chapter describes factor Xa as a key enzyme involved in thrombosis and clot formation. It considers factor Xa inhibitors as potential anticoagulants for the treatment of deep-vein thrombosis and pulmonary embolism. It also highlights the first factor Xa inhibitors to reach the market and covers the design process that led to the discovery of ...
openaire +1 more source
Current Pharmaceutical Design, 1996
Thrombin occupies a central position in thrombus formation and eventually has been a target to develop anticoagulant agents. Although both heparin and warfarin have been used as anticoagulants, a more useful, ideal anticoagulant is desired at bedside.
Satoshi Kunitada, Takayasu Nagahara
openaire +1 more source
Thrombin occupies a central position in thrombus formation and eventually has been a target to develop anticoagulant agents. Although both heparin and warfarin have been used as anticoagulants, a more useful, ideal anticoagulant is desired at bedside.
Satoshi Kunitada, Takayasu Nagahara
openaire +1 more source
2016
This chapter presents an overview of energy dispersive X-ray absorption spectroscopy (EDXAS), as developed and used at synchrotron radiation sources. It mainly covers time resolved studies, with emphasis on technical aspects.
Sakura Pascarelli, Olivier Mathon
openaire +1 more source
This chapter presents an overview of energy dispersive X-ray absorption spectroscopy (EDXAS), as developed and used at synchrotron radiation sources. It mainly covers time resolved studies, with emphasis on technical aspects.
Sakura Pascarelli, Olivier Mathon
openaire +1 more source
2006
The importance of factor Xa in the initiation and propagation of coagulation, as well as its pluripotential cellular properties, has been discussed previously. Considered collectively, the effects exhibited by this particular protease make it an attractive target for pharmacologic inhibition. Factor Xa inhibition can be classified and subcategorized as
Richard C. Becker, Frederick A. Spencer
openaire +1 more source
The importance of factor Xa in the initiation and propagation of coagulation, as well as its pluripotential cellular properties, has been discussed previously. Considered collectively, the effects exhibited by this particular protease make it an attractive target for pharmacologic inhibition. Factor Xa inhibition can be classified and subcategorized as
Richard C. Becker, Frederick A. Spencer
openaire +1 more source
Perspectives in Drug Discovery and Design, 1994
Factor Xa is the serine protease that activates prothrombin to yield thrombin. Inhibitors of factor Xa play a crucial role in curtailing thrombin generation. Two key factor Xa inhibitors that are found in blood are antithrombin III and tissue factor pathway inhibitor.
openaire +1 more source
Factor Xa is the serine protease that activates prothrombin to yield thrombin. Inhibitors of factor Xa play a crucial role in curtailing thrombin generation. Two key factor Xa inhibitors that are found in blood are antithrombin III and tissue factor pathway inhibitor.
openaire +1 more source
European Journal of Clinical Investigation, 2005
P, Bramlage, D, Pittrow, W, Kirch
openaire +2 more sources
P, Bramlage, D, Pittrow, W, Kirch
openaire +2 more sources