Results 51 to 60 of about 214,432 (171)

One Health Insights From Pteropus medius: Nipah Virus Spillover, Microbiota, and Antimicrobial Resistance

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Environmental and anthropogenic drivers of antibiotic resistance dissemination. The cycle reinforces how anthropogenic inputs, such as sewage, animal dung, hospital effluent, and agricultural runoff bring resistant bacteria and antibiotic residues into soil and water.
Punam Chowdhury, Shah Md Tanvir Khan, Sajal Roy, Md. Shohel Al Faruk   +3 more
wiley   +1 more source

MetF‐Dependent Methionine Biosynthesis Is Required for Mycobacterium tuberculosis Survival and In Vivo Persistence

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
MetF is essential for both in vitro and in vivo growth of Mycobacterium tuberculosis, whereas MetE, previously considered essential in vitro, is dispensable in vivo. Given the importance of methionine and folate metabolism as drug targets, MetF represents a promising candidate, highlighting the need for in vivo validation.
Ikue Tosa, Tomoki Kitahara, Katsuki Takebe, Masaaki Nakayama, Yuko Ito, Akihito Nishiyama, Shintaro Seto, Hotaka Kawai, Hiharu Inoue, Yuki Fukada, Yuki Nishiya, Hitoshi Nagatsuka, Takayuki Wada, Manabu Ato, Sohkichi Matsumoto, Naoya Ohara   +15 more
wiley   +1 more source

Drug-resistant Mycobacterium tuberculosis among Nepalese patients at a tuberculosis referral center.

PLoS ONE
BackgroundMultidrug-resistant tuberculosis (MDR-TB), characterized by isoniazid and rifampicin resistance, is caused by chromosomal mutations that restrict treatment options and complicate tuberculosis management.
Arun Bahadur Chand, Ajaya Basnet, Bhagwan Maharjan, Ganesh Rai, Yadav Prasad Joshi, Lok Raj Bhatt, Bindu Sen, Shiba Kumar Rai   +7 more
doaj   +1 more source

Metabolomic analysis of Mycobacterium tuberculosis reveals metabolic profiles for identification of drug-resistant tuberculosis

Scientific Reports, 2023
The detection of pre-extensively (pre-XDR) and extensively drug-resistant tuberculosis (XDR-TB) is challenging. Drug-susceptibility tests for some anti-TB drugs, especially ethambutol (ETH) and ethionamide (ETO), are problematic due to overlapping ...
Pratchakan Chaiyachat, Benjawan Kaewseekhao, Angkana Chaiprasert, Phalin Kamolwat, Ditthawat Nonghanphithak, Jutarop Phetcharaburanin, Auttawit Sirichoat, Rick Twee-Hee Ong, Kiatichai Faksri   +8 more
doaj   +1 more source

Pathogenesis of Tuberculosis: Interplay Between Host Antituberculosis Immunity and Immune Evasion Strategies of Mycobacterium Tuberculosis

MedComm, Volume 7, Issue 8, August 2026.
Mycobacterium tuberculosis–host interactions and infection outcomes. Following initial infection, alveolar macrophages phagocytose the pathogen, prompting the recruitment of innate immune cells including neutrophils, NK cells, and interstitial macrophages.
Xiaojuan Zhang, Ying Liu, Yilin Hou, Hongxia Niu   +3 more
wiley   +1 more source

Pattern for pre-XDR-TB and XDR-TB cases.

This line chart shows the pattern of pre-XDR-TB and XDR-TB across the provinces of Nepal, highlighting the provinces with the highest and lowest prevalence rates of pre-XDR-TB and XDR-TB.
Shiba Kumar Rai (16764697), Ganesh Rai (4421005), Lok Raj Bhatt (18509645), Yadav Prasad Joshi (13910256), Bhagwan Maharjan (292113), Arun Bahadur Chand (16764694), Bindu Sen (18509648), Ajaya Basnet (16764679)   +7 more
core   +1 more source

MDR-TB and XDR-TB: drug resistance and treatment outcomes

, 2009
We read with interest the study by HWANG et al., which continues the discussion on factors associated with poor outcomes in the treatment ofmultidrug-resistant tuberculosis (MDRTB) and extensively drug-resistant tuberculosis (XDR-TB).
Migliori GB, Guenther, G., Sotgiu G, Centis R, Richardson, Morgan D’Arcy, Facchini, A., Facchini A, Migliori, Giovanni Battista, Sotgiu, Giovanni, D'Arcy Richardson M, Lange C., Spanevello, Antonio, Centis, Rosella, Lange, Christoph, Guenther G   +14 more
core   +1 more source

The timing of death in patients with tuberculosis who die during anti-tuberculosis treatment in Andhra Pradesh, South India [PDF]

, 2011
Background: India has 2.0 million estimated tuberculosis (TB) cases per annum with an estimated 280,000 TBrelated deaths per year. Understanding when in the course of TB treatment patients die is important for determining the type of intervention to be ...
Tetali, S, Harries Anthony D, Rao Srinivas, Jonnalagada, Subbanna, Kannuri, Nanda K, Peri, Sundaresh, Kannuri, N K, Srinath Satyanarayana, Peri, S, Peri Sundaresh, Harries, Anthony D, Anchala, Raghupathy, Zachariah Rony, Anchala Raghupathy, Ranganadha Rao, Jonnalagada, S, Rao Ranganadha, Rao, Ranganadha, Jonnalagada Subbanna, Nanda K Kannuri, Zachariah, Rony, Rao, Srinivas, Harries, A D, Rao, S, Shailaja Tetali, Rao, R, Satyanarayana Srinath, Tetali Shailaja, Anthony D Harries, Satyanarayana, Srinath, Zachariah, R, Tetali, Shailaja, Anchala, R, Kannuri Nanda K, Satyanarayana, S, Keshav Chander, G, G Keshav Chander, Keshav Chander G, Sundaresh Peri, Raghupathy Anchala, Subbanna Jonnalagada, Rony Zachariah, Srinivas Rao   +42 more
core   +2 more sources

A Comparative Policy Review of Tuberculosis Infection Control Policies Across Six Countries: Insights on Screening, Prevention, and Treatment Strategies

Health Science Reports, Volume 9, Issue 7, July 2026.
ABSTRACT Background and Aims Tuberculosis (TB) infection remains one of the major global public health challenges, disproportionately affecting vulnerable and marginalized populations. This study aims to compare prevention, screening, and treatment policies for TB in selected countries to identify effective strategies and policy gaps that may inform ...
Mohammad Veysi Sheikhrobat, Sajad Alizadeh, Kamal Shahamiri, Saeed Shahriari, Ahmad Tahmasebi‐Ghorrabi   +4 more
wiley   +1 more source

Linezolid-containing regimens for the treatment of drug-resistant tuberculosis in South African children.

, 2012
BACKGROUND: Treatment options for drug-resistant tuberculosis (DR-TB) are limited. Linezolid has been successfully used to treat DR-TB in adults, but there are few case reports of its use in children for TB.
Rose, PC, Hallbauer, UM, Hesseling, AC, Schaaf, HS, Seddon, JA   +4 more
core   +1 more source