Results 41 to 50 of about 25,286 (218)

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

Medicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva, Alessandra Aiello, Tonino Alonzi, M. Alice Carvalho, Vladimir Finger, Delia Goletti, Sven Hoffner, Yousra Kherabi, Jan Korabecny, Julia Kulczyńska, Agnieszka Kyzioł, Alicia Lacoma, Filomena Martins, Zorica Nanovic, Sepideh Hosseiniporgham, Martina Hrast Rambaher, Leonardo Antonio Sechi, Daria Smalchuk, Grażyna Stochel, Lydia Tabernero, Nancy L. Tateosian, Violeta Valcheva, Anamarija Zega, Mafalda Sarraguça   +23 more
wiley   +1 more source

Combination therapy for carbapenem-resistant gram-negative infections in Ukraine

Infusion & Chemotherapy
. Antimicrobial resistance represents a serious global public health problem and poses a major challenge in the management of combat-related injuries during armed conflicts, such as the war of Russia against Ukraine.
O.V. Moshynets, V.V. Strokous, M.I. Valihurskyi, M.M. Cherniienko, O.V. Kotov, O.A. Golubovska, A.O. Oberniak, F.S. Nikitenko, O.S. Iungin, V.V. Potochilova, K.L. Rudnieva, M.V. Khaitovych   +11 more
doaj   +1 more source

Linezolid for XDR-TB [PDF]

Thorax, 2013
This randomised phase 2a trial in South Korea recruited 41 patients with sputum culture-positive pulmonary extensively drug-resistant tuberculosis (XDR-TB), who had failed to respond to 6 months of available treatment. Daily dosage of 600 mg linezolid was added either immediately or after a delay of two months.
openaire   +1 more source

Boronic Acid Inhibitors of β‐Lactamases: A Promising Strategy Against Antimicrobial Resistance

Medicinal Research Reviews, EarlyView.
ABSTRACT The rise of antimicrobial resistance (AMR) poses a critical threat to global health, mostly due to the proliferation of β‐lactamases, a class of enzymes responsible for the inactivation of β‐lactam antibiotics. Among the most promising strategies to restore β‐lactam efficacy is the use of β‐lactamase inhibitors (BLIs), with boronic acid ...
Nicolò Santi, Federico Corsini, Robert A. Bonomo, Emilia Caselli, Fabio Prati   +4 more
wiley   +1 more source

Epidemiology of Biofilm Producing Acinetobacter baumannii Nosocomial Isolates from a Tertiary Care Hospital in Egypt: A Cross-Sectional Study

Infection and Drug Resistance, 2021
Ahmed Morad Asaad,1 Shamshul Ansari,2 Soma Elsayed Ajlan,3 Samah Mohammed Awad4 1Department of Medical Microbiology and Immunology, Faculty of Medicine, Zagazig University, Zagazig, Egypt; 2Department of Microbiology and Immunology, Chitwan Medical ...
Asaad AM, Ansari S, Ajlan SE, Awad SM
doaj  

Morbidity and Mortality Associated with Typhoid Fever Among Hospitalized Patients in Hyderabad District, Pakistan, 2017-2018: Retrospective Record Review

JMIR Public Health and Surveillance, 2021
BackgroundHyderabad, Pakistan, was the first city to witness an outbreak of extensively drug resistant (XDR) typhoid fever. The outbreak strain is resistant to ampicillin, chloramphenicol, trimethoprim-sulfamethoxazole, fluoroquinolones, and third ...
Fatima, Munaza, Kumar, Santosh, Hussain, Mudassar, Memon, Naveed Masood, Vighio, Anum, Syed, Muhammad Asif, Chaudhry, Ambreen, Hussain, Zakir, Baig, Zeeshan Iqbal, Baig, Mirza Amir, Asghar, Rana Jawad, Ikram, Aamer, Khader, Yousef   +12 more
doaj   +1 more source

Liquid‐Processed 2D Aromatic Amorphous Carbon: Defect Engineering and Universal Transport Scaling

Small, EarlyView.
Liquid‐processed graphene oxide (GO) thin films undergo a controllable crystalline–to–amorphous transition driven by thermal quenching. By kinetically tuning oxygen‐driven defect formation during reduction, scalable 2D aromatic amorphous carbon phases are stabilized, directly linking nanoscale disorder and defect topology to electronic transport ...
Fabiola Liscio, Andrea Fondacaro, Gaetana Petrone, Federico Chianese, Jasper Rikkert Plaisier, Sara Fiori, Orlando Castellano, Alice Apponi, Nicolò Galvani, Verónica Montes García, Veronica Valentini, Stefano Iacobucci, Damiano Ricciarelli, Giuseppe Fisicaro, Antonino Lamagna, Giovanni Maria Vinai, Ernesto Placidi, Alessandro Bellucci, Daniele Maria Trucchi, Paolo Samorì, Alessandro Ruocco, Samuel Lara Avila, Andrea Liscio   +22 more
wiley   +1 more source

Prevalence of Integron Classes in Acinetobacter baumannii Isolated from Patients in Diyala

Medical Journal of Babylon
Background: Acinetobacter baumannii is a worldwide threat that causes infections in hospital settings because of its multidrug resistance to widely available antibiotics.
Noor Nabeel Younis, Lina Abdulameer S. Alsaadi   +1 more
doaj   +1 more source

Multifaceted Behavior and Versatility Features of Ferritic Stainless Steels, Part II: Investigating Electromagnetic, Mechanical, and Corrosion Behavior

steel research international, EarlyView.
This review's second part details the mechanical, corrosion, and electromagnetic behaviors of FSSs. It integrates the foundational microstructure (texture/defects/precipitates) and processing effects from Part I to establish and analyze complex property–property interrelationships critical for high‐performance applications.
Shahab Bazri, Carlo Mapelli, Davide Mombelli   +2 more
wiley   +1 more source

Evaluation of Sensitivity and Resistance of Linezolid in Pre Extensively Drug Resistance Tuberculosis and Extensively Drug Resistance Tuberculosis at a Tertiary Care Hospital, Jamnagar, Gujarat, India [PDF]

Journal of Clinical and Diagnostic Research, 2019
Introduction: The diseases have a high prevalence in India, accounting for one fourth of the Tuberculosis (TB) cases in the world. The situation becomes more complicated due to the rising of Human Immunodeficiency virus/AIDS pandemic, the emergence of ...
Dipali Maganbhai Gavali, Binita Aring, Summiya Mullan, Akhlakahemad A Nathametha, Abhishek B Dave   +4 more
doaj   +1 more source