Results 51 to 60 of about 41,807 (210)

Assessing transporter‐mediated rifampin–linezolid interaction using physiologically‐based pharmacokinetic modelling

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims The study aims to develop a physiologically‐based pharmacokinetic (PBPK) model to quantitatively evaluate the role of ATP‐binding cassette sub‐family B member 1 (ABCB1) and ATP‐binding cassette super‐family G member 2 (ABCG2) in the drug–drug interaction (DDI) between rifampin and linezolid and to predict the impact of high‐dose rifampin ...
Hoang Dat Nguyen   +4 more
wiley   +1 more source

Household screening and multidrug-resistant tuberculosis [PDF]

open access: yes, 2010
Of the estimated half a million people who develop multidrug resistant (MDR) tuberculosis each year, less than 7% are diagnosed and only 1 in 5 of these have access to eff ective treatment.1 To control this epidemic, dramatically increased efforts are ...
Becerra   +9 more
core   +2 more sources

Potent monoclonal antibodies against multidrug‐resistant hypervirulent Klebsiella pneumoniae

open access: yesInterdisciplinary Medicine, EarlyView.
A novel immunization strategy using a low‐virulence, multidrug‐resistant strain yields synergistic monoclonal antibodies against hypervirulent Klebsiella pneumoniae. These antibodies provide cross‐serotype protection through a dual‐mechanism of pathogen clearance and immunomodulation, offering a promising non‐antibiotic therapeutic for resistant ...
Yushan Jiang   +10 more
wiley   +1 more source

Molecular gas chemistry in AGN. II. High-resolution imaging of SiO emission in NGC1068: shocks or XDR? [PDF]

open access: yes, 2010
This paper is part of a multi-species survey of line emission from the molecular gas in the circum-nuclear disk (CND) of the Seyfert 2 galaxy NGC1068. Single-dish observations have provided evidence that the abundance of silicon monoxide(SiO) in the CND ...
A. Fuente   +87 more
core   +3 more sources

Prevalence of Integron Classes in Acinetobacter baumannii Isolated from Patients in Diyala

open access: yesMedical Journal of Babylon
Background: Acinetobacter baumannii is a worldwide threat that causes infections in hospital settings because of its multidrug resistance to widely available antibiotics.
Noor Nabeel Younis   +1 more
doaj   +1 more source

Epidemiology of Biofilm Producing Acinetobacter baumannii Nosocomial Isolates from a Tertiary Care Hospital in Egypt: A Cross-Sectional Study

open access: yesInfection and Drug Resistance, 2021
Ahmed Morad Asaad,1 Shamshul Ansari,2 Soma Elsayed Ajlan,3 Samah Mohammed Awad4 1Department of Medical Microbiology and Immunology, Faculty of Medicine, Zagazig University, Zagazig, Egypt; 2Department of Microbiology and Immunology, Chitwan Medical ...
Asaad AM, Ansari S, Ajlan SE, Awad SM
doaj  

Clusters of Drug-Resistant Mycobacterium tuberculosis Detected by Whole-Genome Sequence Analysis of Nationwide Sample, Thailand, 2014–2017

open access: yesEmerging Infectious Diseases, 2021
Multidrug-resistant tuberculosis (MDR TB), pre-extensively drug-resistant tuberculosis (pre-XDR TB), and extensively drug-resistant tuberculosis (XDR TB) complicate disease control.
Ditthawat Nonghanphithak   +12 more
doaj   +1 more source

Dense circum-nuclear molecular gas in starburst galaxies [PDF]

open access: yes, 2016
We present results from a study of the dense circum-nuclear molecular gas of starburst galaxies. The study aims to investigate the interplay between starbursts, active galactic nuclei and molecular gas. We characterise the dense gas traced by HCN, HCO$^{+
Baan, Willem A.   +9 more
core   +2 more sources

MDR, XDR, TDR tuberculosis: ominous progression [PDF]

open access: yesThorax, 2012
> Any man's death diminishes me because I am involved in mankind, and therefore never send to know for whom the bell tolls; it tolls for thee… (John Donne, Meditation XV11) > The growing TB epidemic is no longer an emergency only for those who care about health, but also for those who care about justice. (P D O Davies) For 2 weeks in January, India
openaire   +2 more sources

Liquid‐Processed 2D Aromatic Amorphous Carbon: Defect Engineering and Universal Transport Scaling

open access: yesSmall, EarlyView.
Liquid‐processed graphene oxide (GO) thin films undergo a controllable crystalline–to–amorphous transition driven by thermal quenching. By kinetically tuning oxygen‐driven defect formation during reduction, scalable 2D aromatic amorphous carbon phases are stabilized, directly linking nanoscale disorder and defect topology to electronic transport ...
Fabiola Liscio   +22 more
wiley   +1 more source

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