Results 41 to 50 of about 214,432 (171)

Treatment Practices, Outcomes, and Costs of Multidrug-Resistant and Extensively Drug-Resistant Tuberculosis, United States, 2005–2007

Emerging Infectious Diseases, 2014
To describe factors associated with multidrug-resistant (MDR), including extensively-drug-resistant (XDR), tuberculosis (TB) in the United States, we abstracted inpatient, laboratory, and public health clinic records of a sample of MDR TB patients ...
Suzanne M. Marks, Jennifer Flood, Barbara Seaworth, Yael Hirsch-Moverman, Lori Armstrong, Sundari Mase, Katya Salcedo, Peter Oh, Edward A. Graviss, Paul W. Colson, Lisa Armitige, Manuel Revuelta, Kathryn Sheeran   +12 more
doaj   +1 more source

Minimal Diversity of Drug-Resistant Mycobacterium tuberculosis Strains, South Africa

Emerging Infectious Diseases, 2014
Multidrug- (MDR) and extensively drug-resistant tuberculosis (XDR TB) are commonly associated with Beijing strains. However, in KwaZulu-Natal, South Africa, which has among the highest incidence and mortality for MDR and XDR TB, data suggest that non ...
Neel R. Gandhi, James C.M. Brust, Prashini Moodley, Darren Weissman, Moonseong Heo, Yuming Ning, Anthony P. Moll, Gerald H. Friedland, A. Willem Sturm, N. Sarita Shah   +9 more
doaj   +1 more source

Laboratory-confirmed DR, pre-XDR, and XDR-TB cases reported in the Free State, South Africa, from 2019 to 2022, according to previous and updated WHO definitions

International Journal of Infectious Diseases
Introduction: The global challenge of Tuberculosis (TB) control persists, particularly in addressing drug-resistant (DR) TB across regions. Over time, the rise in rifampicin (RIF/R) resistance, multi-drug resistant TB (MDR-TB, characterised until 2022 by
Miss Zothile Skosana, Miss Likhona Dingiswayo, Mrs Anneke Van Der Spoel Van Dijk   +2 more
doaj   +1 more source

The Relationship between Extensively Drug-Resistant Tuberculosis and Multidrug-Resistant Gram-Negative Bacilli.

PLoS ONE, 2015
ObjectiveThe relationship between extensively drug-resistant tuberculosis (XDR-TB) and multidrug-resistant Gram-negative bacilli (MDR-GNB) is unclear.
Jiang-Nan Zhao, Xian-Xin Zhang, Xiao-Chun He, Guo-Ru Yang, Xiao-Qi Zhang, Huai-Chen Li   +5 more
doaj   +1 more source

Multidrug- and Extensively Drug-Resistant Tuberculosis, Germany

Emerging Infectious Diseases, 2008
We evaluated risk factors and treatment outcomes associated with multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB) in Germany in 2004–2006. In 177 (4%) of 4,557 culture-positive TB cases, Mycobacterium tuberculosis isolates
Barbara Eker, Johannes Ortmann, Giovanni B. Migliori, Giovanni Sotgiu, Ralf Muetterlein, Rosella Centis, Harald Hoffmann, Detlef Kirsten, Tom Schaberg, Sabine Ruesch-Gerdes, Christoph Lange   +10 more
doaj   +1 more source

Design, Synthesis, Antimycobacterial Evaluation, and In Silico Investigation of Benzisothiazole‐Based Hydrazide Derivatives as Potential Anti‐Tuberculosis Agents

Chemical Biology &Drug Design, Volume 108, Issue 3, September 2026.
A novel series of benzisothiazole‐based hydrazide derivatives was designed, synthesized, and evaluated for antitubercular activity. Compound 8k emerged as the most potent candidate (MIC = 0.25 μg/mL) with a high selectivity index (SI = 42) and bactericidal activity. Molecular docking and 100 ns simulations identified InhA as the probable target.
Vivek Sharma, Arun Sharma, Ruchi Poria, Pardeep Kumar   +3 more
wiley   +1 more source

Extensively Drug-Resistant Tuberculosis, Burkina Faso

Emerging Infectious Diseases, 2010
Because data from countries in Africa are limited, we measured the proportion of extensively drug-resistant (XDR) tuberculosis (TB) cases among TB patients in Burkina Faso for whom retreatment was failing.
Nuccia Saleri, Gisèle Badoum, Martial Ouedraogo, Sary M. Dembélé, Rachel Nacanabo, Victor Bonkoungou, Daniela Cirillo, Gabriele Pinsi, Alberto Matteelli   +8 more
doaj   +1 more source

Adverse events in bedaquiline‐ and pretomanid‐based regimens for drug‐resistant tuberculosis from trial, implementation and pharmacovigilance studies

British Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2607-2623, August 2026.
Abstract The availability of safety data, particularly concerning adverse events (AEs) associated with the new shorter regimen for drug‐resistant tuberculosis (TB) containing a bedaquiline–pretomanid‐based regimen, is still limited. This systematic review aims to provide a comprehensive and updated analysis of AEs related to this new regimen by ...
Nisa Maria, Annisa Lazuardi Larasati, Indri Yuliani Hamdani, Jin‐Gun Cho, Jan‐Willem C. Alffenaar   +4 more
wiley   +1 more source

EXTENSIVELY DRUG RESISTANT TUBERCULOSIS (XDR TB) [PDF]

, 2019
Tuberkulosis adalah penyakit infeksi kronis menular yang masih merupakan masalah kesehatan masyarakat di dunia termasuk Indonesia. Tuberkulosis (TB) sebagian besar akan mengalami penyembuhan dengan pengobatan.
Siregar, Sarah Rahmayani
core   +1 more source

Treatment outcomes of patients with multidrug and extensively drug-resistant tuberculosis in Zhejiang, China

European Journal of Medical Research, 2021
Background The aim of this study was to assess the treatment outcomes of multidrug and extensively drug-resistant tuberculosis (M/XDR-TB) in Zhejiang, China and to evaluate possible risk factors associated with poor outcomes of M/XDR-TB.
Ming-Wu Zhang, Lin Zhou, Yu Zhang, Bin Chen, Ying Peng, Fei Wang, Zheng-Wei Liu, Xiao-Meng Wang, Song-Hua Chen   +8 more
doaj   +1 more source