Results 1 to 10 of about 93,298 (256)

Physical and functional interaction of the ciliopathy proteins Lrrc56 and Odad3 control deployment of axonemal dyneins in vertebrate multiciliated cells

open access: yesDisease Models & Mechanisms
Nayeli G. Reyes-Nava   +5 more
doaj   +2 more sources

The TFIIH complex is required to establish and maintain mitotic chromosome structure

open access: yeseLife, 2022
Condensins compact chromosomes to promote their equal segregation during mitosis, but the mechanism of condensin engagement with and action on chromatin is incompletely understood.
Julian Haase   +5 more
doaj   +1 more source

Rab7 is required for mesoderm patterning and gastrulation in Xenopus

open access: yesBiology Open, 2021
Early embryogenesis requires tightly controlled temporal and spatial coordination of cellular behavior and signaling. Modulations are achieved at multiple levels, from cellular transcription to tissue-scale behavior.
Jennifer Kreis   +2 more
doaj   +1 more source

Zmym4 is required for early cranial gene expression and craniofacial cartilage formation

open access: yesFrontiers in Cell and Developmental Biology, 2023
Introduction: The Six1 transcription factor plays important roles in the development of cranial sensory organs, and point mutations underlie craniofacial birth defects.
Karyn Jourdeuil   +6 more
doaj   +1 more source

Capillary Electrophoresis Mass Spectrometry for Scalable Single-Cell Proteomics

open access: yesFrontiers in Chemistry, 2022
Understanding the biochemistry of the cell requires measurement of all the molecules it produces. Single-cell proteomics recently became possible through advances in microanalytical sample preparation, separation by nano-flow liquid chromatography ...
Bowen Shen   +8 more
doaj   +1 more source

Morphological, acoustic and genetic identification of a reproducing population of the invasive African clawed frog Xenopus laevis (Anura, Pipidae) recently discovered in Belgium [PDF]

open access: yesZooKeys, 2023
Using external morphology of adults and tadpoles, osteology from high-resolution microcomputed tomography, vocalization analysis, and DNA sequence data, the identity of a reproducing Belgian population of invasive Xenopus at the current northernmost edge
Olivier S. G. Pauwels   +5 more
doaj   +3 more sources

MiR-9 and the Midbrain-Hindbrain Boundary: A Showcase for the Limited Functional Conservation and Regulatory Complexity of MicroRNAs

open access: yesFrontiers in Cell and Developmental Biology, 2020
MicroRNAs regulate gene expression at post-transcriptional levels. Some of them appear to regulate brain development and are involved in neurodevelopmental disorders.
A. Alwin Prem Anand   +2 more
doaj   +1 more source

Age-associated DNA methylation changes in Xenopus frogs

open access: yesEpigenetics, 2023
Age-associated changes in DNA methylation have been characterized across various animals, but not yet in amphibians, which are of particular interest because they include widely studied model organisms.
Marco Morselli   +5 more
doaj   +1 more source

Xenopus Cdc7 executes its essential function early in S phase and is counteracted by checkpoint-regulated protein phosphatase 1 [PDF]

open access: yesOpen Biology, 2014
The initiation of DNA replication requires two protein kinases: cyclin-dependent kinase (Cdk) and Cdc7. Although S phase Cdk activity has been intensively studied, relatively little is known about how Cdc7 regulates progression through S phase.
Wei Theng Poh   +4 more
doaj   +1 more source

Developing immortal cell lines from Xenopus embryos, four novel cell lines derived from Xenopus tropicalis

open access: yesOpen Biology, 2022
The diploid anuran Xenopus tropicalis has emerged as a key research model in cell and developmental biology. To enhance the usefulness of this species, we developed methods for generating immortal cell lines from Nigerian strain (NXR_1018, RRID ...
Gary J. Gorbsky   +8 more
doaj   +1 more source

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