Results 1 to 10 of about 167,815 (303)

Xenbase: Facilitating the Use of Xenopus to Model Human Disease

Frontiers in Physiology, 2019
At a fundamental level most genes, signaling pathways, biological functions and organ systems are highly conserved between man and all vertebrate species. Leveraging this conservation, researchers are increasingly using the experimental advantages of the
Mardi J. Nenni, Malcolm E. Fisher, Christina James-Zorn, Troy J. Pells, Virgilio Ponferrada, Stanley Chu, Joshua D. Fortriede, Kevin A. Burns, Ying Wang, Vaneet S. Lotay, Dong Zhou Wang, Erik Segerdell, Praneet Chaturvedi, Kamran Karimi, Peter D. Vize, Aaron M. Zorn   +15 more
doaj   +2 more sources

Genetics, Morphology, Advertisement Calls, and Historical Records Distinguish Six New Polyploid Species of African Clawed Frog (Xenopus, Pipidae) from West and Central Africa.

PLoS ONE, 2015
African clawed frogs, genus Xenopus, are extraordinary among vertebrates in the diversity of their polyploid species and the high number of independent polyploidization events that occurred during their diversification.
Ben J Evans, Timothy F Carter, Eli Greenbaum, Václav Gvoždík, Darcy B Kelley, Patrick J McLaughlin, Olivier S G Pauwels, Daniel M Portik, Edward L Stanley, Richard C Tinsley, Martha L Tobias, David C Blackburn   +11 more
doaj   +2 more sources

Physical and functional interaction of the ciliopathy proteins Lrrc56 and Odad3 control deployment of axonemal dyneins in vertebrate multiciliated cells

Disease Models & Mechanisms
Nayeli G. Reyes-Nava, Chanjae Lee, Ophelia Papoulas, Juyeon Hong, Edward M. Marcotte, John B. Wallingford   +5 more
doaj   +2 more sources

Xenbase: key features and resources of the Xenopus model organism knowledgebase

Genetics, 2023
Xenbase (https://www.xenbase.org/), the Xenopus model organism knowledgebase, is a web-accessible resource that integrates the diverse genomic and biological data from research on the laboratory frogs Xenopus laevis and Xenopus tropicalis.
M. Fisher, Christina James-Zorn, V. Ponferrada, Andrew J Bell, Nivitha Sundararaj, E. Segerdell, P. Chaturvedi, Nadia Bayyari, Stanley Chu, Troy J. Pells, Vaneet Lotay, S. Agalakov, Dong Zhou Wang, Bradley I. Arshinoff, Saoirse Foley, K. Karimi, P. Vize, A. Zorn   +17 more
semanticscholar   +1 more source

Zmym4 is required for early cranial gene expression and craniofacial cartilage formation

Frontiers in Cell and Developmental Biology, 2023
Introduction: The Six1 transcription factor plays important roles in the development of cranial sensory organs, and point mutations underlie craniofacial birth defects.
Karyn Jourdeuil, Karen M. Neilson, Helene Cousin, Andre L. P. Tavares, Himani D. Majumdar, Dominique Alfandari, Sally A. Moody   +6 more
doaj   +1 more source

Normal Table of Xenopus development: a new graphical resource

Development, 2022
Normal tables of development are essential for studies of embryogenesis, serving as an important resource for model organisms, including the frog Xenopus laevis.
Natalya Zahn, Christina James-Zorn, V. Ponferrada, D. Adams, J. Grzymkowski, D. Buchholz, Nanette M. Nascone-Yoder, M. Horb, S. Moody, P. Vize, A. Zorn   +10 more
semanticscholar   +1 more source

The TFIIH complex is required to establish and maintain mitotic chromosome structure

eLife, 2022
Condensins compact chromosomes to promote their equal segregation during mitosis, but the mechanism of condensin engagement with and action on chromatin is incompletely understood.
Julian Haase, Richard Chen, Wesley M Parker, Mary Kate Bonner, Lisa M Jenkins, Alexander E Kelly   +5 more
doaj   +1 more source

Rab7 is required for mesoderm patterning and gastrulation in Xenopus

Biology Open, 2021
Early embryogenesis requires tightly controlled temporal and spatial coordination of cellular behavior and signaling. Modulations are achieved at multiple levels, from cellular transcription to tissue-scale behavior.
Jennifer Kreis, Fee M. Wielath, Philipp Vick   +2 more
doaj   +1 more source

Capillary Electrophoresis Mass Spectrometry for Scalable Single-Cell Proteomics

Frontiers in Chemistry, 2022
Understanding the biochemistry of the cell requires measurement of all the molecules it produces. Single-cell proteomics recently became possible through advances in microanalytical sample preparation, separation by nano-flow liquid chromatography ...
Bowen Shen, Leena R. Pade, Sam B. Choi, Pablo Muñoz-LLancao, Pablo Muñoz-LLancao, Pablo Muñoz-LLancao, M. Chiara Manzini, M. Chiara Manzini, Peter Nemes   +8 more
doaj   +1 more source

MiR-9 and the Midbrain-Hindbrain Boundary: A Showcase for the Limited Functional Conservation and Regulatory Complexity of MicroRNAs

Frontiers in Cell and Developmental Biology, 2020
MicroRNAs regulate gene expression at post-transcriptional levels. Some of them appear to regulate brain development and are involved in neurodevelopmental disorders.
A. Alwin Prem Anand, Gonzalo Alvarez-Bolado, Andrea Wizenmann   +2 more
doaj   +1 more source