Results 131 to 140 of about 91,354 (252)

Prioritising research on endocrine disruption in the marine environment: a global perspective

Biological Reviews, Volume 101, Issue 2, Page 848-868, April 2026.
ABSTRACT A healthy ocean is a crucial life support system that regulates the global climate, is a source of oxygen and supports major economic activities. A vast and understudied biodiversity from micro‐ to macro‐organisms is integral to ocean health.
Patricia I. S. Pinto, Angelica Miglioli, Carlie A. LaLone, Lisa Baumann, Alice Baynes, Mélanie Blanc‐Legendre, Ibon Cancio, Xavier Cousin, ZhiChao Dang, Rémi Dumollard, Alex T. Ford, Christopher Green, Taisen Iguchi, Philippa Kearney, Thomas Knigge, Christophe Minier, Tiphaine Monsinjon, Marta S. Monteiro, Joachim Sturve, Haruna Watanabe, Hiroshi Yamamoto, Gerald Ankley, Deborah M. Power, Ioanna Katsiadaki   +23 more
wiley   +1 more source

Exposure to the Oestrogenic Pollutant 17α‐Ethinyl Estradiol (EE2) Does Not Alter the Behaviour of a Coastal Marine Fish, Cristiceps australis

Ethology, Volume 132, Issue 4, Page 295-304, April 2026.
Environmental contamination with the synthetic estrogen 17α‐ethinyl estradiol (EE2) is widespread in coastal ecosystems, yet behavioural effects in marine fishes remain poorly understood. We exposed southern crested weedfish (Cristiceps australis) to low and high EE2 concentrations for 14 days and assessed boldness and anxiety using a refuge‐use assay.
Shiho Ozeki, Rhiannon V. Eastment, Jack L. Manera, Raiko Rafeeq, Anne Peters, Jake M. Martin, Bob B. M. Wong   +6 more
wiley   +1 more source

Zebrafish as a model for Catel–Manzke syndrome—identification and characterization of the zebrafish TGDS ortholog

The FEBS Journal, Volume 293, Issue 8, Page 2248-2269, April 2026.
Zebrafish Tgds, when expressed as a recombinant protein, catalyzes the dehydration of UDP‐D‐glucose, the initial step in the formation of 6‐deoxyhexoses. Corresponding Tgds mutations found in Catel–Manzke syndrome patients lead to reduced enzymatic activity and stability.
Maria Rosaria Coppola, Deianira Bellitto, Erfan Asgari, Virginia Bazzurro, Giorgia Casucci, Francesco Piacente, Matteo Bozzo, Davide Ceresa, Costantino Parisi, Cecilia Winata, Simona Candiani, Michela Tonetti   +11 more
wiley   +1 more source

OsPT4 Facilitates Selenomethionine Transport and Biosynthesis to Enhance Seed Accumulation in Rice: Molecular Mechanisms and Biotechnological Potential

Plant Biotechnology Journal, Volume 24, Issue 4, Page 1992-2008, April 2026.
ABSTRACT Selenium (Se) is a vital micronutrient for humans, with important functions for health and anti‐cancer properties. Organic Se shows higher antioxidant activity and much lower toxicity compared to inorganic Se, making it safer for use. Selenomethionine (SeMet) is one of the primary forms of organic Se.
Yang Yang, Lijuan Sun, Jia Wei, Fang Zhang, Shiyan Yang, Jiarui Zhang, Qin Qin, Jun Wang, Guohua Xu, Shubin Sun, Yafei Sun, Yong Xue   +11 more
wiley   +1 more source

Xenopus laevis [PDF]

, 2020
openaire   +1 more source

Differential negative dominance by KCNA2 variants associated with global developmental delay suggests KCNA2 haploinsufficiency in humans

The Journal of Physiology, Volume 604, Issue 8, Page 3413-3430, 15 April 2026.
Abstract figure legend Potassium‐selective KV1.2 channels are encoded by the KCNA2 gene and regulate electrical signalling in neurons. KCNA2 genetic variants are associated with epileptic and developmental encephalopathy. We characterized two variants that subtly alter the channel's amino acid composition, p.H310D and p.G318D.
Pei Xin Boon, Amaia Jauregi‐Miguel, S. Suheda Yasarbas, Serena Pozzi, Urban Karlsson, Ammar Husami, Charmaine Ko, Amelle Shillington, Antonios Pantazis   +8 more
wiley   +1 more source

Altered functional interactions between CFTR disease mutants ΔF508 and G551D and the protein kinase A catalytic subunit

The Journal of Physiology, Volume 604, Issue 8, Page 3344-3362, 15 April 2026.
Abstract figure legend Pathogenic mutations ΔF508 and G551D of the cystic fibrosis transmembrane conductance regulator (CFTR) channel alter its interactions with protein kinase A (PKA). Top left, for both mutants, but not for wild‐type (WT) CFTR, non‐catalytic stimulation of channel activity by PKA is larger in the presence of N6‐(2‐phenylethyl)‐ATP (P‐
Olivér Závoti, Márton A. Simon, László Csanády   +2 more
wiley   +1 more source

Genome‐wide identification and solute selectivity of aquaporins in the sharpnose sevengill shark, Heptranchias perlo

Physiological Reports, Volume 14, Issue 8, April 2026.
Abstract The aquaporin genes (aqps) are widely distributed among vertebrates. In cartilaginous fish, aqp3 and aqp10 are duplicated, whereas many species have lost aqp8. While the solute permeability of aquaglyceroporins and Aqp8 exhibits significant diversity, systematic evaluations of their activity within species are limited.
Shinichiro Hidaka, Ayumi Nagashima, Akira Kato   +2 more
wiley   +1 more source

Sperm Cells as DNA Vectors for the Preparation of Transgenic Animals

CHIMIA, 1999
Sperm-mediated DNA transfer strategy which has been used for the preparation of genetically modified, transgenic organisms is discussed, and sperm-mediated transgenesis of Xenopus laevis frogs with retroviral Rous sarcoma virus DNA is summarized.
Jiří Jonák
doaj  

Pre-marking chromatin with H3K4 methylation is required for accurate zygotic genome activation and development

Nature Communications
In vertebrate embryos, gene expression is first initiated at zygotic genome activation (ZGA). Maternally expressed transcription factors are essential for this process.
Meghana S. Oak, Marco Stock, Ana Janeva, Matthias Mezes, Antony M. Hynes-Allen, Tobias Straub, Ignasi Forné, Andreas Ettinger, Stephan Hamperl, Axel Imhof, Jelle van den Ameele, Antonio Scialdone, Eva Hörmanseder   +12 more
doaj   +1 more source