Results 111 to 120 of about 91,354 (252)

Selectivity Filter Dynamics Define Ion Conductance and Selectivity Differences in CNG and HCN Channels

open access: yesAdvanced Science, Volume 13, Issue 22, 17 April 2026.
Cyclic nucleotide‐gated (CNG) and hyperpolarization‐activated cyclic nucleotide‐gated (HCN) channels share substantial sequence and structural similarity but differ markedly in ion conductance and K+ selectivity. Microsecond‐scale atomistic MD simulations qualitatively reproduced the conductance differences observed in single‐channel recordings and ...
Haoran Liu   +3 more
wiley   +1 more source

Synapsids and sensitivity: Broad survey of tetrapod trigeminal canal morphology supports an evolutionary trend of increasing facial tactile specialization in the mammal lineage

open access: yesThe Anatomical Record, Volume 309, Issue 4, Page 864-911, April 2026.
Abstract The trigeminus nerve (cranial nerve V) is a large and significant conduit of sensory information from the face to the brain, with its three branches extending over the head to innervate a wide variety of integumentary sensory receptors, primarily tactile.
Juri A. Miyamae   +4 more
wiley   +1 more source

Divergent roles of the Wnt/PCP Formin Daam1 in renal ciliogenesis.

open access: yesPLoS ONE, 2019
Kidneys are composed of numerous ciliated epithelial tubules called nephrons. Each nephron functions to reabsorb nutrients and concentrate waste products into urine.
Mark E Corkins   +5 more
doaj   +1 more source

Rubrolides A, D, P, T, U: Total Syntheses and Antibacterial Evaluation of Highly Brominated Marine Natural Products

open access: yesChemistryEurope, Volume 4, Issue 4, April 2026.
Following the Danube Flow. The first total syntheses of highly brominated rubrolides T, U, and U‐analog, together with the efficient and divergent syntheses of rubrolides A, D, and P. The dibrominated key intermediate, obtained via a Suzuki‐Miyaura cross‐coupling reaction, is the centerpiece of the synthesis.
Jasmin Janneschütz   +7 more
wiley   +1 more source

Fluorescent Calcium Imaging and Subsequent In Situ Hybridization for Neuronal Precursor Characterization in Xenopus laevis [PDF]

open access: yes, 2020
Spontaneous intracellular calcium activity can be observed in a variety of cell types and is proposed to play critical roles in a variety of physiological processes.
Ablondi, Eileen F.   +7 more
core  

Pathological Roles of Astrocytes in Traumatic Brain Injury

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.
TBI induces intrinsic astrocytic changes, including reactive astrogliosis, A1 and A2 polarization, ion channels activation, pathological edema, oxidative stress, and metabolic dysregulation. These injury‐responsive astrocytes regulate neuroinflammation and tissue remodeling through dynamic crosstalk with microglia, macrophages, vascular endothelial ...
Di Wu   +7 more
wiley   +1 more source

Limb Regeneration in Xenopus laevis Froglet

open access: yesThe Scientific World Journal, 2006
Limb regeneration in amphibians is a representative process of epimorphosis. This type of organ regeneration, in which a mass of undifferentiated cells referred to as the “blastema” proliferate to restore the lost part of the amputated organ, is distinct
Makoto Suzuki   +5 more
doaj   +1 more source

Metamorphosis and lncRNAs: A Close Relationship

open access: yesgenesis, Volume 64, Issue 2, April 2026.
ABSTRACT The classical definition of metamorphosis is a post‐embryonic transformation, such as from a tadpole to a froglet. However, recent studies suggest this process occurs to some degree in all vertebrates, as the underlying endocrine and molecular pathways are highly conserved. With the advent of high‐throughput sequencing, transcriptomic data for
H. Herrera‐Orozco   +1 more
wiley   +1 more source

Xwnt-5A: a maternal Wnt that affects morphogenetic movements after overexpression in embryos of Xenopus laevis [PDF]

open access: yes, 1993
To contribute to an understanding of the roles and mechanisms of action of Wnts in early vertebrate development, we have characterized the normal expression of Xenopus laevis Wnt-5A, and investigated the consequences of misexpression of this putative ...
Campbell, Robert M.   +5 more
core  

Hybridization and Immunology in Animals: A Review

open access: yesEcology and Evolution, Volume 16, Issue 4, April 2026.
Hybridization can reshape immune function by introducing novel genetic variation and combining parental immune traits. Across animal taxa, this process may influence resistance, tolerance, and pathogen dynamics, with important implications for disease ecology and One Health.
Cheyenne R. Graham   +3 more
wiley   +1 more source

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