Results 101 to 110 of about 88,575 (229)
Early Head Specification in Xenopus laevis
The Scientific World Journal, 2003 The head represents the most dorsal and anterior extent of the body axis. In Xenopus, the progressive determination of the head is an extremely complex process involving the activation and localized antagonism of a number of interdependent intracellular ...
Blue B. Lake, Kenneth R. Kao
doaj +1 more source
The Many Faces of Xenopus: Xenopus laevis as a Model System to Study Wolf–Hirschhorn Syndrome
Frontiers in Physiology, 2019 Wolf–Hirschhorn syndrome (WHS) is a rare developmental disorder characterized by intellectual disability and various physical malformations including craniofacial, skeletal, and cardiac defects.
Micaela Lasser +4 more
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A Cytosine‑Bulged (3+1) Hybrid G‑Quadruplex Formed by the Chicken DNA Replication Origin
Chemistry – A European Journal, Volume 32, Issue 39, 22 October 2026.The first high‐resolution structure of an OGRE‐derived G‐quadruplex from the chicken β‐globin replication origin reveals an intramolecular three‐layer (3+1) hybrid fold with a cytosine bulge and an unprecedented 5'‐outer‐quartet anti guanine, creating a distinctive surface for molecular recognition.
Yingying You +13 more
wiley +1 more source
Multitarget Drug Design for Cardiovascular Disease: Bridging Chemistry and Medicine
ChemMedChem, Volume 21, Issue 19, 14 October 2026.Many pathophysiological pathways associated with cardiovascular diseases involve multiple drug targets. This article reviews recent advances in the development of pharmacological compounds capable of simultaneously modulating multiple mechanisms. Multitarget drugs offer a promising therapeutic approach for complex cardiovascular disorders, including ...
Gyuzel Y. Mitronova +3 more
wiley +1 more source
Frontiers in Cell and Developmental BiologySpinal cord injury (SCI) results in severe disruption of communication between the brain and body, causing motor, sensory, and autonomic dysfunctions. While SCI in mammals leads to permanent impairment due to limited regenerative capacity, certain non ...
Paula G. Slater +8 more
doaj +1 more source
An analysis of wnt signalling molecules in Xenopus pronephros development [PDF]
The aim of the project was to characterise known wnt signalling molecules during the early pronephros patterning using novel and effective bioassays in Xenopus embryos.
Tételin, Stéphanie
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Functional studies of cytokines produced by Xenopus Lymphocytes following T cell mitogen stimulation [PDF]
, 1992 In vitro culture conditions for the production and assay of T cell mitogen - induced culture supernatants have been investigated in an amphibian model system, the clawed toad, Xenopus.
Hoi-Jen Ho, Jocelyn
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A direct requirement for Xmus101 in ATR-mediated phosphorylation of Claspin bound Chk1 during checkpoint signaling. [PDF]
, 2006 TopBP1-like proteins, which include Xenopus laevis Xmus101, are required for DNA replication and have been linked to replication checkpoint control. A direct role for TopBP1/Mus101 in checkpoint control has been difficult to prove, however, because of ...
Lindsay, Howard D. +2 more
core +2 more sources
Cell & Bioscience, 2012 Background Thyroid hormone (T3) is important for adult organ function and vertebrate development. Amphibian metamorphosis is totally dependent on T3 and offers a unique opportunity to study how T3 controls postembryonic development in vertebrates ...
Matsuura Kazuo +5 more
doaj +1 more source
Investigations into Xpat, a novel gene expressed in the germ plasm and primordial germ cells of Xenopus laevis [PDF]
To determine the expression pattern of XPAT (Xenopus primordial germ cell associated transcript) protein in Xenopus oocytes, XPAT-GFP fusion proteins were generated.
McCormick, Rachel Jacqueline
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