Results 51 to 60 of about 107,754 (235)

Sex-specific functional evolution of Dmrt1 in African clawed frogs (Xenopus), and the importance of genetic tipping points in developmental biology.

PLoS Genetics
The doublesex and mab-3 related transcription factor 1 (dmrt1) plays a crucial role in metazoan sexual differentiation. This gene, or its paralogs, independently became triggers for sex determination several times, including in the tetraploid African ...
Lindsey M Kukoly, Sarah R Porter, Danielle C Jordan, Heather A Murphy, Martin Knytl, Nikko Shaidani, William R Thomas, Carl Anderson, Ian Dworkin, Marko E Horb, Ben J Evans   +10 more
doaj   +1 more source

Probing the Xenopus laevis inner ear transcriptome for biological function

BMC Genomics, 2012
Background The senses of hearing and balance depend upon mechanoreception, a process that originates in the inner ear and shares features across species.
Powers TuShun R, Virk Selene M, Trujillo-Provencio Casilda, Serrano Elba E   +3 more
doaj   +1 more source

Protocol to study human Kv1.2 potassium channel pathogenic sequence variants using two-electrode voltage-clamp technique

STAR Protocols
Summary: The abietane diterpenoid pisiferic acid (PA) from conifer Chamaecyparis pisifera is a pan-rescuer of human Kv1.2 channel pathogenic loss-of-function (LOF) sequence variants.
Rían W. Manville, Geoffrey W. Abbott
doaj   +1 more source

DEADSouth protein localizes to germ plasm and is required for the development of primordial germ cells in Xenopus laevis

Biology Open, 2012
Summary DEADSouth mRNA is a component of germ plasm in Xenopus laevis and encodes a DDX25 DEAD-box RNA helicase. To determine the intracellular localization of DEADSouth protein, we injected mRNA encoding DEADSouth tagged with mCherry fluorescent protein
Takeshi Yamaguchi, Ayaka Taguchi, Kenji Watanabe, Hidefumi Orii   +3 more
doaj   +1 more source

XenDB: Full length cDNA prediction and cross species mapping in Xenopus laevis

BMC Genomics, 2005
Background Research using the model system Xenopus laevis has provided critical insights into the mechanisms of early vertebrate development and cell biology. Large scale sequencing efforts have provided an increasingly important resource for researchers.
Giegerich Robert, Brivanlou Ali H, Beckstette Michael, Sczyrba Alexander, Altmann Curtis R   +4 more
doaj   +1 more source

Association of TCTP with Centrosome and Microtubules

Biochemistry Research International, 2012
Translationally Controlled Tumour Protein (TCTP) associates with microtubules (MT), however, the details of this association are unknown. Here we analyze the relationship of TCTP with MTs and centrosomes in Xenopus laevis and mammalian cells using ...
Mariusz K. Jaglarz, Franck Bazile, Katarzyna Laskowska, Zbigniew Polanski, Franck Chesnel, Ewa Borsuk, Malgorzata Kloc, Jacek Z. Kubiak   +7 more
doaj   +1 more source

Development of Antimicrobial Peptides from Amphibians

Antibiotics, 2020
Since the discovery of magainins from the skin secretions of the African toad Xenopus laevis by Michael Zasloff in 1987, an increasing number of antimicrobial peptides (AMPs) has been identified in different anuran species and studied in detail [...]
Maria Luisa Mangoni, Bruno Casciaro
doaj   +1 more source

Early Head Specification in Xenopus laevis

The Scientific World Journal, 2003
The head represents the most dorsal and anterior extent of the body axis. In Xenopus, the progressive determination of the head is an extremely complex process involving the activation and localized antagonism of a number of interdependent intracellular ...
Blue B. Lake, Kenneth R. Kao
doaj   +1 more source

The Many Faces of Xenopus: Xenopus laevis as a Model System to Study Wolf–Hirschhorn Syndrome

Frontiers in Physiology, 2019
Wolf–Hirschhorn syndrome (WHS) is a rare developmental disorder characterized by intellectual disability and various physical malformations including craniofacial, skeletal, and cardiac defects.
Micaela Lasser, Benjamin Pratt, Connor Monahan, Seung Woo Kim, Laura Anne Lowery   +4 more
doaj   +1 more source

L'activiation de l'oeuf de Xenopus laevis laevis

Revue suisse de zoologie., 1965
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
Ortolani, G, Vanderhaeghe, F.
openaire   +2 more sources