Results 61 to 70 of about 91,354 (252)

Xenopus laevis Oocytes

, 2003
Xenopus oocytes are a versatile expression system particularly suited for membrane transporters and channels. Oocytes have little background activity and therefore offer a very high signal-to-noise ratio for transporter and channel characterization. This chapter provides an overview of the basic methods used for the analysis of membrane transporters in
openaire   +4 more sources

Experimental Embryology in Xenopus Laevis

Turkish Journal of Biology, 1997
Xenopus laevis Türk bilim adamları için yeni bir hayvan modelidir. Ana amacımız, laboratuvarımızda FETAX testini (Frog Embryos Teratogenesis Assay: Xenopus) kurmaktır. Bu çalışmada, Xenopus'un geniş kullanım alanları tanıtıldıktan sonra laboratuvar koşullarında üreme, besleme, havalandırma ve populasyon yoğunluğu parametreleri sunuldu.
Ayper Boğa, Seçil Binokay, Ayşe Kendirci, Tuncay Özgünen   +3 more
openaire   +2 more sources

The role of Rho GTPases in facial morphogenesis

Developmental Dynamics, EarlyView.
The role of small GTPases, RHOA, RAC1, and CDC42 and pathway mediators is reviewed in the context of embryonic facial development. Lip fusion requires cytoskeletal remodeling during morphogenesis of the facial processes and during lip fusion. Fnm, frontonasal mass; lnp, lateral nasal process; mnp, medial nasal process; mxp, maxillary process; np, nasal
Isra Ibrahim, Joy M. Richman
wiley   +1 more source

A maternal dorsoventral prepattern revealed by an asymmetric distribution of ventralizing molecules before fertilization in Xenopus laevis

Frontiers in Cell and Developmental Biology
The establishment of the embryonic dorsoventral axis in Xenopus occurs when the radial symmetry around the egg’s animal-vegetal axis is broken to give rise to the typical symmetry of Bilaterians.
Aitana M. Castro Colabianchi, Aitana M. Castro Colabianchi, Nicolás G. González Pérez, Nicolás G. González Pérez, Lucía F. Franchini, Silvia L. López, Silvia L. López   +6 more
doaj   +1 more source

Effective RNAi-mediated β2-microglobulin loss of function by transgenesis in Xenopus laevis

Biology Open, 2013
Summary To impair MHC class I (class I) function in vivo in the amphibian Xenopus, we developed an effective reverse genetic loss of function approach by combining I-SceI meganuclease-mediated transgenesis with RNAi technology.
Hristina Nedelkovska, Eva-Stina Edholm, Nikesha Haynes, Jacques Robert   +3 more
doaj   +1 more source

Of Frogs & Rhetoric: The Atrazine Wars [PDF]

, 2015
In a scientific dispute over the effects of atrazine on amphibians, chemical industry–funded and publically funded scientists present stunningly contrasting constructions of atrazine\u27s environmental concentrations, persistence, and potential to harm ...
Reeves, Carol
core   +2 more sources

Role of SoxE transcription factors in development and disease

Developmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

A role for glyceraldehyde-3-phosphate dehydrogenase in the development of thermotolerance in Xenopus laevis embryos [PDF]

, 1988
During heat shock, Xenopus laevis embryos exhibit an increase in the rate of accumulation of lactate and a loss of ATP relative to non-heat- shocked control embryos.
Browder, Leon W., Nickells, Robert W.
core   +2 more sources

KCNJ4 variants disrupt inward‐rectifier potassium channel function and cause refractory epilepsy

Epilepsia, EarlyView.
Abstract Objective Epilepsy is a common neurological disorder with a strong genetic basis, most frequently arising from ion channel dysfunction. Although multiple inwardly rectifying potassium (Kir) channels have been implicated in epileptogenesis, the contribution of KCNJ4, which encodes the Kir2.3 channel, has not previously been established in human
Hu Pan, Deng Liu, Wuhen Xu, Yang Li, Juanli Hu, Oppermann Henry, Alexander Fuchs, Rami Abou Jamra, Zhen Liu, Mei He, Yuanlu Chen, Shengnan Wu, Xiaohuan Dong, Yiqiao Chen, Pengchao Wang, Weiyue Gu, Han Jing, Yabing Tang, Ya‐Jie Wang, Xiao Mao, Neng Xiao   +20 more
wiley   +1 more source

The epithelium of the dorsal marginal zone of Xenopus has organizer properties [PDF]

, 1992
We have investigated the properties of the epithelial layer of the dorsal marginal zone (DMZ) of the Xenopus laevis early gastrula and found that it has inductive properties similar to those of the entire Spemann organizer.
Keller, Ray, Shih, John
core