Results 61 to 70 of about 157,699 (364)

The distribution of Dishevelled in convergently extending mesoderm [PDF]

, 2013
Convergent extension (CE) is a conserved morphogenetic movement that drives axial lengthening of the primary body axis and depends on the planar cell polarity (PCP) pathway.
Aigouy, Axelrod, Axelrod, Bosgraaf, Ciruna, Cohen, Concha, Dale, Darken, Davidson, Deardorff, Devenport, Djiane, Dormann, Eaton, Eleni Panousopoulou, Gao, Gimlich, Goto, Gray, Green, Heisenberg, Jeremy B.A. Green, Jiang, Karner, Keller, Keller, Keller, Keller, Keller, Keller, Kibar, Kinoshita, Mlodzik, Ossipova, Park, Richard A. Tyson, Rothbacher, Roy, Sanders, Schwarz-Romond, Selchow, Shih, Shih, Shindo, Shulman, Sive, Strutt, Till Bretschneider, Ueno, Usui, Vinson, Wallingford, Wallingford, Wallingford, Wang, Wilson, Wilson, Wong, Yang-Snyder, Yin, Zallen   +61 more
core   +1 more source

Mitotic waves in an import-diffusion model with multiple nuclei in a shared cytoplasm [PDF]

arXiv, 2021
Nuclei import and export proteins, including cell cycle regulators. These import-export processes are modulated periodically by the cell cycle, for example due to the periodic assembly and breakdown of the nuclear envelope. As such, replicated DNA can be segregated between the two daughter cells and the proteins that were localized in the nucleus are ...
arxiv  

Changes of statistical structural fluctuations unveils an early compacted degraded stage of PNS myelin [PDF]

Scientific Reports 4, 5430 (2014), 2013
Degradation of the myelin sheath is a common pathology underlying demyelinating neurological diseases from Multiple Sclerosis to Leukodistrophies. Although large malformations of myelin ultrastructure in the advanced stages of Wallerian degradation is known, its subtle structural variations at early stages of demyelination remains poorly characterized.
arxiv   +1 more source

Acquisition of Leftward Flow in Xenopus laevis

Bio-Protocol, 2013
In Xenopus, the left-right axis is established following an extracellular vectorial leftward flow driven by monocilia at the gastrocoel roof plate (GRP) during late gastrulation / neurulation (Schweickert et al., 2007).
Thomas Thumberger, Martin Blum
doaj   +1 more source

Advances in CRISPR‐Cas9 in lineage tracing of model animals

Animal Models and Experimental Medicine, EarlyView.
Cell lineage tracing is a key technology for describing the developmental history of individual progenitor cells and assembling them to form a lineage development tree. However, traditional methods have limitations of poor stability and insufficient resolution.
Jingchao Cao, Zihang Guo, Xueling Xu, Pan Li, Yi Fang, Shoulong Deng   +5 more
wiley   +1 more source

Xenopus: An ideal system for chemical genetics [PDF]

, 2012
Chemical genetics, or chemical biology, has become an increasingly powerful method for studying biological processes. The main objective of chemical genetics is the identification and use of small molecules that act directly on proteins, allowing rapid ...
Adams, Adams, Almogy, Banaszynski, Blackiston, Blackiston, Brändli, Cambridge, Carneiro, Chae, Chang, Chen, Clark, Dale, Das, Davidson, Deiters, Dodd, Dupre, Dush, Fini, Frank-Kamenetsky, Fukumoto, Garcia-Morales, Goda, Grammer, Hanvey, Hartley, Heasman, Horb, Huang, Kalin, Kolm, Lennox, Levin, Liu, Liu, Liu, Longo, Love, Lund, Meijer, Morckel, Nielsen, Nusslein-Volhard, Obika, Paddison, Page-McCaw, Peterson, Peterson, Pownall, Rankin, Reya, Richards, Rones, Schneider, Shestopalov, Stankunas, Tomlinson, Tomlinson, Tomlinson, Tomlinson, Tomlinson, Van Raay, Vandenberg, Verma, Wahlestedt, Walsh, Wheeler, Wheeler, White, Wignall, Woolf, Yang   +73 more
core   +1 more source

Correlated disorder in myelinated axons orientational geometry and structure [PDF]

Condens. Matter 2(3), 29 (2017), 2017
While the ultrastructure of the myelin has been considered to be a quasi-crystalline stable system, nowadays its multiscale complex dynamics appears to play a key role for its functionality, degeneration and repair processes following neurological diseases and trauma.
arxiv   +1 more source

Lipids of Xenopus laevis Spermatozoa [PDF]

Development, Growth & Differentiation, 1992
Xenopus laevis sperm lipid composition has been studied. The cholesterol content of Xenopus spermatozoa is 194 μ/mg DNA. Their content of glycolipids and phospholipids (measured as inorganic phosphorus) is respectively 40 and 27 μ/mg DNA. The phospholipid pattern is quite homogeneous and all the principal molecular species are present.
BERNARDINI, GIOVANNI BATTISTA, GORNATI, ROSALBA, RAPELLI S., ROSSI, FEDERICA, BERRA B.   +4 more
openaire   +4 more sources

HCN2‐Associated Neurodevelopmental Disorders: Data from Patients and Xenopus Cell Models

Annals of Neurology, EarlyView.
Objective We aimed to characterize the phenotypic spectrum and functional consequences associated with variants in HCN2, encoding for the hyperpolarization‐activated cyclic nucleotide (HCN) gated channel 2. Methods GeneMatcher facilitated the recruitment of 21 individuals with HCN2 variants from 15 unrelated families, carrying HCN2 variants.
Clara Houdayer, A. Marie Phillips, Marie Chabbert, Jennifer Bourreau, Reza Maroofian, Henry Houlden, Kay Richards, Nebal Waill Saadi, Eliška Dad'ová, Patrick Van Bogaert, Mailys Rupin, Boris Keren, Perrine Charles, Thomas Smol, Audrey Riquet, Lynn Pais, Anne O'Donnell‐Luria, Grace E. VanNoy, Allan Bayat, Rikke S Møller, Kern Olofsson, Rami Abou Jamra, Steffen Syrbe, Majed Dasouki, Laurie H. Seaver, Jennifer A. Sullivan, Vandana Shashi, Fowzan S. Alkuraya, Alexis F. Poss, J. Edward Spence, Rhonda E. Schnur, Ian C. Forster, Chaseley E. Mckenzie, Cas Simons, Min Wang, Penny Snell, Kavitha Kothur, Michael Buckley, Tony Roscioli, Noha Elserafy, Benjamin Dauriat, Vincent Procaccio, Daniel Henrion, Guy Lenaers, Estelle Colin, Nienke E. Verbeek, Koen L. Van Gassen, Claire Legendre, Dominique Bonneau, Christopher A. Reid, Katherine B. Howell, Alban Ziegler, Christian Legros   +52 more
wiley   +1 more source

Paradigm Shifts In Neural Induction [PDF]

, 2000
The molecularization of developmental biology was originally seen as a challenge to the integrity of that discipline. However, important new insights from the analysis of gene expression soon transformed the field from one of experimental anatomy to one ...
Gilbert, Scott F.
core   +2 more sources