Results 131 to 140 of about 29,864 (273)

Characteristic, Regulation and Targeting Strategies of Cancer Stem Cells and Their Niche in Digestive System Tumors

open access: yesMedComm – Oncology, Volume 4, Issue 2, June 2025.
Cancer stem cells, characterized by self‐renewal, differentiation, heterogeneity, plasticity and tumorigenicity, are regulated by intrinsic factors such as signaling pathways, transcription factors, metabolism and noncoding RNAs, as well as environmental cells (including tumor cells, immune cells and stromal cells), environmental factors and distant ...
Zhenzhen Chen   +11 more
wiley   +1 more source

Artificial Intelligence for Organoids Multidimensional Assessment

open access: yesSmartMat, Volume 6, Issue 3, June 2025.
This review provides a comprehensive analysis and discussion of the current applications of artificial intelligence (AI) technologies in the evaluation of organoids. It summarizes and synthesizes the primary methods and standards for organoid assessment, offering new insights for researchers engaged in the interdisciplinary field of AI and organoid ...
Yulin Mo   +5 more
wiley   +1 more source

Generation and transcriptomic characterization of MIR137 knockout miniature pig model for neurodevelopmental disorders

open access: yesCell & Bioscience
Background Neurodevelopmental disorders (NDD), such as autism spectrum disorders (ASD) and intellectual disorders (ID), are highly debilitating childhood psychiatric conditions.
Shengyun Xu   +15 more
doaj   +1 more source

Is Zebrafish a Good Model for the Alpha‐Gal Syndrome?

open access: yesThe FASEB Journal, Volume 39, Issue 9, 15 May 2025.
ABSTRACT The alpha‐Gal syndrome (AGS) is an underdiagnosed tick‐borne allergy characterized by both immediate and delayed IgE‐mediated anaphylactic reactions to the galactose‐alpha‐1,3‐galactose (alpha‐Gal) epitope. Common manifestations include gastrointestinal, cutaneous, and respiratory symptoms appearing 2–6 h after the consumption of mammalian ...
Rita Vaz‐Rodrigues, José de la Fuente
wiley   +1 more source

A Remarkable Journey of Porcine to Human Xenotransplantation

open access: yesIndian Journal of Transplantation
Xenotransplantation of pig hearts offers a potential solution to the scarcity of available human organs for transplantation. This abstract explores the challenges and risks associated with xenotransplantation, as well as the ongoing research and ...
Dhruva Sharma   +1 more
doaj   +1 more source

Profound thrombocytopenia associated with administration of multiple anti‐inflammatory agents in baboons

open access: yesImmunity, Inflammation and Disease, 2022
Mohamed H. Bikhet   +7 more
doaj   +1 more source

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