Results 151 to 160 of about 35,510 (301)

Expression and Functional of LncRNA XIST in MCF-7 Breast Cancer Cells

open access: yesZhongliu Fangzhi Yanjiu, 2019
Objective To investigate the expression and function of lncRNA XIST in MCF-7 breast cancer cells. Methods The expression of XIST in MCF 10A human normal breast epithelial cells and MCF-7 human breast cancer cells were detected by qRT-PCR.
HOU Xia   +10 more
doaj   +1 more source

Role of lncRNA XIST/miR-146a Axis in Matrix Degradation and Apoptosis of Osteoarthritic Chondrocytes Through Regulation of MMP-13 and BCL2

open access: yesBiology
Growing evidence demonstrates the critical roles of long non-coding RNAs (lncRNAs) in osteoarthritis (OA) pathogenesis. The lncRNA XIST is one of the most commonly studied; however, its function remains unclear. This study aimed to research the molecular
Sara Cheleschi   +6 more
doaj   +1 more source

X chromosome inactivation: Activation of Silencing [PDF]

open access: yes, 2009
X chromosome inactivation is a process that ensures equal expression of the X chromosomes between males, which have one X and one Y chromosome, and females, which have two X chromosomes, in mammals.
Jonkers, I.H. (Iris)
core   +1 more source

Xist induction following p53 disability features SynJ1 modulation.

open access: yes, 2023
We recently described a sex-specific transcriptional regulation mechanism, found in physiologically relevant settings in breast cancer cells in vitro and in cells of the embryo in mice and humans, wherein mutation or loss of the p53 tumor suppressor results in transcriptional perturbation of the non-coding RNA that functions in X-inactivation, Xist ...
openaire   +1 more source

Xist spatially amplifies SHARP/SPEN recruitment to balance chromosome-wide silencing and specificity to the X chromosome

open access: yesNature Structural & Molecular Biology, 2022
Joanna W. Jachowicz   +5 more
semanticscholar   +1 more source

Slow construction and design of a family house turns into a spatial education experience: three challenges 6 facts. [PDF]

open access: yes, 2014
Ponencia presentada a Session 1: Educación y arquitectura: fundamentos teóricos / Education and architecture: theoretical ...
Cardells, Paula   +2 more
core  

Independent recruitment of PRC1 and PRC2 by human XIST [PDF]

open access: gold, 2020
Thomas Dixon-McDougall, Carolyn J. Brown
openalex   +1 more source

FUNCTIONAL ROLE OF VIMENTIN'S CYSTEINE IN XIST-MEDIATED EMT INHIBITION IN BREAST CANCER

open access: yesJournal of Stem Cell Research and Tissue Engineering
Breast cancer is the most commonly diagnosed malignancy among women worldwide and a leading cause of cancer-related mortality, primarily due to its high metastatic potential. One mechanism underlying metastasis is the epithelial-to-mesenchymal transition
Jayanti   +4 more
doaj   +1 more source

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