Results 131 to 140 of about 16,717 (221)

XIST Gene [PDF]

, 2020
openaire   +1 more source

Dissection of Xist Functional Elements Involved in X-Chromosome Inactivation

, 2019
X-chromosome inactivation (XCI) is the epigenetic process of silencing one of the two X chromosomes in female mammals to balance X-linked gene dosage with that of males. This process is governed by the long noncoding RNA Xist.
Colognori, David A.
core  

XIST Loss Induces Variable Transcriptional Responses Dependent on Cell States

Background/Objectives: The X-inactivation specific transcript (XIST) is a long noncoding RNA playing a crucial regulatory role in X chromosome inactivation (XCI)—a transcriptional regulatory process that silences one of the two X chromosomes in ...
Jie Wu, Dongning Chen, Sha Sun, Ikrame Naciri   +3 more
core   +1 more source

Long non-coding RNA (lncRNA) XIST drives TGF-β-induced renal cancer progression via miR-141-3p/ZEB1 signaling. [PDF]

Transl Androl Urol
Hu X, Deng M, Li D, Yang J, Xie M, Wang P, Zhan J, Long M, Meng X, Yang C, Che X, Deng K.   +11 more
europepmc   +1 more source

LncRNA-XIST Competitively Binds to MicroRNA-532-5p to Regulate PTEN Expression, Exacerbating Cerebral Ischemia-Reperfusion Injury. [PDF]

Adv Biol (Weinh)
Lu X, Chen L, Qian L, Zhang X, Wang Y, Yu B.   +5 more
europepmc   +1 more source

Control of Xist by BRCA1.

We previously demonstrated control of the non-coding RNA that functions in dosage compensation in humans with two X chromosomes (females), Xist, by the two major cellular tumor suppressors, p53 and Rb1, and demonstrated that activation of Xist occurs in females with breast cancer and in males with lung cancer, finding that aberrant Xist modulation ...
openaire   +2 more sources

Association Between Serum lncRNA XIST Levels and Depressive Disorder

Long non-coding RNA (lncRNA) XIST has been implicated in the pathogenesis of depression, yet its precise role in the disorder remains inadequately understood.
Peng, Rui
core   +1 more source

Female mice with a Xist deletion in B cells can develop lupus-associated phenotypes. [PDF]

Cell Rep
Lovell CD, Jiwrajka N, Toothacre NE, Amerman HK, Cancro MP, Anguera MC.   +5 more
europepmc   +1 more source

Exploring the functional role of XIST in breast cancer from mechanisms to clinical implications. [PDF]

Discov Oncol
Zyada NI, Kamel MM, Elzayat EM, Wahab AHAA.   +3 more
europepmc   +1 more source

Context-dependent roles of lncRNA JPX in human cancers. [PDF]

Discov Oncol
Li Y, Li T, Li J, Su Y, Liu Y, Chen L, Pan Y, Ma J, Gong T, Hu H.   +9 more
europepmc   +1 more source